SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4i3m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 4i3m AEROTAXIS TRANSDUCER
AER2
(Pseudomonas
aeruginosa) 		4 / 6 PHE A 130
ALA A 124
GLY A 126
TYR A 125
 None
 0.96A 1c8lA-4i3mA:
undetectable		 1c8lA-4i3mA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 4i3m AEROTAXIS TRANSDUCER
AER2
(Pseudomonas
aeruginosa) 		4 / 6 PHE A 130
ALA A 124
GLY A 126
TYR A 125
 None
 1.00A 1gfzA-4i3mA:
undetectable		 1gfzA-4i3mA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4i3m AEROTAXIS TRANSDUCER
AER2
(Pseudomonas
aeruginosa) 		4 / 6 PHE A 130
ALA A 124
GLY A 126
TYR A 125
 None
 0.98A 1l5qA-4i3mA:
undetectable		 1l5qA-4i3mA:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4i3m AEROTAXIS TRANSDUCER
AER2
(Pseudomonas
aeruginosa) 		4 / 6 PHE A 130
ALA A 124
GLY A 126
TYR A 125
 None
 0.96A 1l5qB-4i3mA:
undetectable		 1l5qB-4i3mA:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4i3m AEROTAXIS TRANSDUCER
AER2
(Pseudomonas
aeruginosa) 		4 / 6 PHE A 130
ALA A 124
GLY A 126
TYR A 125
 None
 0.95A 1l7xB-4i3mA:
undetectable		 1l7xB-4i3mA:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)		 4i3m AEROTAXIS TRANSDUCER
AER2
(Pseudomonas
aeruginosa) 		3 / 3 ALA A 110
HIS A 111
VAL A 114
 None
 0.36A 1lqtB-4i3mA:
undetectable		 1lqtB-4i3mA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)		 4i3m AEROTAXIS TRANSDUCER
AER2
(Pseudomonas
aeruginosa) 		3 / 3 ALA A 110
HIS A 111
VAL A 114
 None
 0.36A 1lquB-4i3mA:
undetectable		 1lquB-4i3mA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 4i3m AEROTAXIS TRANSDUCER
AER2
(Pseudomonas
aeruginosa) 		4 / 9 ILE A 148
ARG A 152
ALA A 124
VAL A 121
 None
SO4  A 202 (-3.0A)
None
None
 1.07A 2vufB-4i3mA:
undetectable		 2vufB-4i3mA:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 4i3m AEROTAXIS TRANSDUCER
AER2
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 130
ALA A 124
GLY A 126
TYR A 125
 None
 1.02A 3bcrA-4i3mA:
undetectable		 3bcrA-4i3mA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4i3m AEROTAXIS TRANSDUCER
AER2
(Pseudomonas
aeruginosa) 		4 / 6 PHE A 130
ALA A 124
GLY A 126
TYR A 125
 None
 0.93A 3dd1A-4i3mA:
undetectable		 3dd1A-4i3mA:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4i3m AEROTAXIS TRANSDUCER
AER2
(Pseudomonas
aeruginosa) 		4 / 6 PHE A 130
ALA A 124
GLY A 126
TYR A 125
 None
 0.96A 3ddsA-4i3mA:
undetectable		 3ddsA-4i3mA:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4i3m AEROTAXIS TRANSDUCER
AER2
(Pseudomonas
aeruginosa) 		4 / 6 PHE A 130
ALA A 124
GLY A 126
TYR A 125
 None
 0.95A 3ddsB-4i3mA:
undetectable		 3ddsB-4i3mA:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4i3m AEROTAXIS TRANSDUCER
AER2
(Pseudomonas
aeruginosa) 		4 / 6 PHE A 130
ALA A 124
GLY A 126
TYR A 125
 None
 0.96A 3ddwA-4i3mA:
undetectable		 3ddwA-4i3mA:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4i3m AEROTAXIS TRANSDUCER
AER2
(Pseudomonas
aeruginosa) 		4 / 6 PHE A 130
ALA A 124
GLY A 126
TYR A 125
 None
 0.95A 3ddwB-4i3mA:
undetectable		 3ddwB-4i3mA:
11.91