SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4i3s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4i3s OUTER DOMAIN OF
HIV-1 GP120 (KER2018
OD4.2.2)
(Human
immunodeficiency
virus) 		3 / 3 ARG G 350
GLU G 397
THR G 399
 None
 0.91A 3v4tA-4i3sG:
undetectable		 3v4tA-4i3sG:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_C_QMRC1214_1
(CAPITELLA TELETA
ACHBP)		 4i3s OUTER DOMAIN OF
HIV-1 GP120 (KER2018
OD4.2.2)
(Human
immunodeficiency
virus) 		4 / 8 TYR G 384
CYH G 418
CYH G 385
ILE G 294
 None
 0.90A 4afgD-4i3sG:
undetectable
4afgE-4i3sG:
undetectable		 4afgD-4i3sG:
20.17
4afgE-4i3sG:
20.17