SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4i4k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4i4k UNCHARACTERIZED
PROTEIN SGCJ
(Streptomyces
globisporus) 		3 / 3 TRP A  29
HIS A  63
MET A  64
 None
CIT  A 201 (-3.6A)
None
 1.38A 1l5qB-4i4kA:
undetectable		 1l5qB-4i4kA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 4i4k UNCHARACTERIZED
PROTEIN SGCJ
(Streptomyces
globisporus) 		5 / 12 LEU A  21
ILE A  25
ALA A 120
VAL A 121
PHE A  37
 None
 1.25A 2qo6A-4i4kA:
undetectable		 2qo6A-4i4kA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4i4k UNCHARACTERIZED
PROTEIN SGCJ
(Streptomyces
globisporus) 		5 / 10 ILE A 100
THR A  75
VAL A  77
ILE A  78
SER A 109
 None
None
PG4  A 202 (-4.7A)
None
None
 1.43A 3kpbD-4i4kA:
undetectable		 3kpbD-4i4kA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA502_0
(OXIDOREDUCTASE,
FMN-BINDING)		 4i4k UNCHARACTERIZED
PROTEIN SGCJ
(Streptomyces
globisporus) 		4 / 7 TRP A 118
ASN A 134
TYR A 132
LEU A  49
 PG4  A 202 (-4.8A)
PG4  A 202 (-3.4A)
PG4  A 202 (-4.5A)
PG4  A 202 ( 4.6A)
 1.35A 4awuA-4i4kA:
undetectable		 4awuA-4i4kA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4i4k UNCHARACTERIZED
PROTEIN SGCJ
(Streptomyces
globisporus) 		4 / 7 THR A  75
HIS A  63
LEU A  49
ASN A 134
 None
CIT  A 201 (-3.6A)
PG4  A 202 ( 4.6A)
PG4  A 202 (-3.4A)
 1.02A 4pfjA-4i4kA:
undetectable		 4pfjA-4i4kA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_1
(PROTEASE PR5-SQV)		 4i4k UNCHARACTERIZED
PROTEIN SGCJ
(Streptomyces
globisporus) 		5 / 9 ASN A 134
ALA A 116
ILE A  82
GLY A  79
ILE A  78
 PG4  A 202 (-3.4A)
PG4  A 202 ( 3.8A)
None
PG4  A 202 ( 3.9A)
None
 1.24A 5kr2A-4i4kA:
undetectable		 5kr2A-4i4kA:
22.76