SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4i59'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD6_0
(GRAMICIDIN A)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		3 / 3 TRP A 237
ALA A 242
VAL A 244
 None
 0.93A 1av2C-4i59A:
undetectable
1av2D-4i59A:
undetectable		 1av2C-4i59A:
5.66
1av2D-4i59A:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		5 / 12 GLN A 468
VAL A 464
LEU A 103
THR A 101
TRP A 237
 None
 1.27A 1dmyB-4i59A:
undetectable		 1dmyB-4i59A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		3 / 3 SER A 185
GLU A 186
GLU A 187
 None
 0.68A 1eqbD-4i59A:
undetectable		 1eqbD-4i59A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		3 / 3 SER A 185
GLU A 186
GLU A 187
 None
 0.68A 1eqbB-4i59A:
undetectable		 1eqbB-4i59A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		5 / 12 ALA A 471
ALA A 470
LEU A  50
ALA A  49
VAL A 273
 None
 0.96A 1fbyA-4i59A:
undetectable		 1fbyA-4i59A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		5 / 12 ALA A 471
ALA A 470
LEU A  50
ALA A  49
VAL A 273
 None
 0.96A 1fbyB-4i59A:
undetectable		 1fbyB-4i59A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		4 / 5 ILE A  97
LEU A  96
VAL A 464
ALA A 290
 None
 0.99A 1mz9C-4i59A:
undetectable		 1mz9C-4i59A:
6.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		3 / 3 ASP A 347
THR A 345
GLU A 187
 None
 0.76A 1pj7A-4i59A:
15.1		 1pj7A-4i59A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		5 / 12 ILE A  36
GLY A  43
GLY A  68
VAL A 288
LEU A  50
 None
None
FAD  A 501 (-3.1A)
None
None
 1.07A 1vptA-4i59A:
undetectable		 1vptA-4i59A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		5 / 12 ALA A 471
ALA A 470
LEU A  50
ALA A  49
VAL A 273
 None
 0.93A 1xdkE-4i59A:
undetectable		 1xdkE-4i59A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_0
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		5 / 12 ILE A 369
GLY A 370
GLY A 201
GLY A 349
TRP A 377
 None
 1.00A 2fk8A-4i59A:
undetectable		 2fk8A-4i59A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		3 / 3 ALA A 242
VAL A 244
TRP A 237
 None
 0.96A 2izqA-4i59A:
undetectable
2izqB-4i59A:
undetectable		 2izqA-4i59A:
5.66
2izqB-4i59A:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		4 / 6 THR A 413
ARG A 320
ASN A  63
ASP A  64
 None
None
FAD  A 501 (-4.6A)
None
 1.32A 2okcA-4i59A:
undetectable		 2okcA-4i59A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		4 / 7 TRP A 456
TYR A 211
TYR A 214
TYR A 459
 None
None
None
FAD  A 501 (-4.4A)
 1.10A 2ph9A-4i59A:
undetectable
2ph9B-4i59A:
undetectable		 2ph9A-4i59A:
19.46
2ph9B-4i59A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		5 / 12 GLY A  43
GLY A  40
VAL A 288
VAL A 464
GLY A 463
 None
FAD  A 501 (-3.5A)
None
None
FAD  A 501 ( 4.5A)
 0.75A 2qe6A-4i59A:
undetectable		 2qe6A-4i59A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		5 / 12 GLY A  43
GLY A  40
VAL A 288
VAL A 464
GLY A 463
 None
FAD  A 501 (-3.5A)
None
None
FAD  A 501 ( 4.5A)
 0.74A 2qe6B-4i59A:
undetectable		 2qe6B-4i59A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		3 / 3 GLY A 371
GLY A 319
GLY A 201
 None
 0.44A 3bogC-4i59A:
undetectable		 3bogC-4i59A:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		5 / 12 ILE A  37
GLY A  38
VAL A  60
ILE A  66
ALA A 290
 FAD  A 501 (-4.7A)
FAD  A 501 (-3.2A)
None
None
None
 0.90A 3fpjA-4i59A:
undetectable		 3fpjA-4i59A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_2
(ADENOSYLHOMOCYSTEINA
SE)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		4 / 5 GLN A 223
GLU A  91
THR A  92
HIS A  93
 None
 1.29A 3glqB-4i59A:
2.0		 3glqB-4i59A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		5 / 12 GLY A 367
GLN A 325
VAL A 324
MET A 460
ILE A 369
 None
None
None
FAD  A 501 (-4.4A)
None
 1.22A 3h52B-4i59A:
undetectable		 3h52B-4i59A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		5 / 12 VAL A 156
LEU A 200
THR A 424
GLY A 435
LEU A 438
 None
 1.09A 3j6pB-4i59A:
undetectable		 3j6pB-4i59A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		5 / 12 ILE A  41
GLY A  40
GLY A  43
ALA A  47
ILE A 248
 FAD  A 501 (-4.5A)
FAD  A 501 (-3.5A)
None
None
None
 1.02A 3jayA-4i59A:
undetectable		 3jayA-4i59A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		3 / 3 TRP A 237
ALA A 242
VAL A 244
 None
 1.01A 3l8lA-4i59A:
undetectable
3l8lB-4i59A:
undetectable		 3l8lA-4i59A:
5.66
3l8lB-4i59A:
3.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		4 / 5 GLN A 223
GLU A  91
THR A  92
HIS A  93
 None
 1.34A 3n58A-4i59A:
undetectable		 3n58A-4i59A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O02_B_JN3B1_1
(CELL INVASION
PROTEIN SIPD)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		5 / 10 ARG A 327
ILE A 366
ALA A 326
LEU A 352
LEU A 393
 None
 1.11A 3o02A-4i59A:
undetectable
3o02B-4i59A:
undetectable		 3o02A-4i59A:
22.87
3o02B-4i59A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OAP_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		5 / 12 ALA A 471
ALA A 470
LEU A  50
ALA A  49
VAL A 273
 None
 0.96A 3oapA-4i59A:
undetectable		 3oapA-4i59A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		4 / 5 LEU A 105
GLY A 100
ILE A  41
VAL A 464
 None
None
FAD  A 501 (-4.5A)
None
 0.64A 3wriA-4i59A:
undetectable		 3wriA-4i59A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		4 / 5 LEU A 105
GLY A 100
ILE A  41
VAL A 464
 None
None
FAD  A 501 (-4.5A)
None
 0.64A 3wriB-4i59A:
undetectable		 3wriB-4i59A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		4 / 5 LEU A 105
GLY A 100
ILE A  41
VAL A 464
 None
None
FAD  A 501 (-4.5A)
None
 0.67A 3wrkA-4i59A:
undetectable		 3wrkA-4i59A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		4 / 6 SER A 405
GLU A 386
ASP A 391
ASP A 403
 None
 1.33A 4blvA-4i59A:
undetectable		 4blvA-4i59A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		3 / 3 GLY A 111
SER A 110
TRP A 236
 None
 0.64A 4e7cD-4i59A:
undetectable		 4e7cD-4i59A:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		4 / 8 TYR A 118
VAL A 194
LEU A 143
LEU A 146
 None
 0.93A 4l1xA-4i59A:
undetectable		 4l1xA-4i59A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		5 / 12 GLY A 421
GLY A 201
GLY A 371
ASN A 373
ALA A 418
 None
 0.84A 4uciA-4i59A:
undetectable		 4uciA-4i59A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		5 / 12 GLY A 421
GLY A 201
GLY A 371
ASN A 373
ALA A 418
 None
 0.84A 4uciB-4i59A:
undetectable		 4uciB-4i59A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		5 / 12 GLY A 421
GLY A 201
GLY A 371
ASN A 373
ALA A 418
 None
 0.85A 4uckA-4i59A:
undetectable		 4uckA-4i59A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UG5_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		3 / 3 ARG A  65
THR A 410
TRP A 412
 None
None
FAD  A 501 (-3.7A)
 1.19A 4ug5A-4i59A:
undetectable		 4ug5A-4i59A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		5 / 12 LYS A 173
VAL A 175
LEU A 152
ALA A 148
TRP A 212
 None
 1.09A 4ygfG-4i59A:
undetectable		 4ygfG-4i59A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESJ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		4 / 8 PHE A 257
ILE A  66
GLY A  43
LEU A  99
 None
 0.92A 5esjA-4i59A:
undetectable		 5esjA-4i59A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		5 / 12 GLY A  38
GLY A  43
ILE A  66
ILE A 289
LEU A  58
 FAD  A 501 (-3.2A)
None
None
None
None
 1.09A 5fa8A-4i59A:
undetectable		 5fa8A-4i59A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6C_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		3 / 3 ARG A  65
THR A 410
TRP A 412
 None
None
FAD  A 501 (-3.7A)
 1.18A 5g6cA-4i59A:
undetectable		 5g6cA-4i59A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		5 / 12 ALA A 471
ALA A 470
LEU A  50
ALA A  49
VAL A 273
 None
 0.91A 5z12B-4i59A:
undetectable		 5z12B-4i59A:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		5 / 12 ALA A 471
ALA A 470
LEU A  50
ALA A  49
VAL A 273
 None
 0.96A 5z12C-4i59A:
undetectable		 5z12C-4i59A:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA605_0
(ALPHA-AMYLASE)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		4 / 8 TYR A 459
GLY A 463
ILE A  41
HIS A  93
 FAD  A 501 (-4.4A)
FAD  A 501 ( 4.5A)
FAD  A 501 (-4.5A)
None
 0.92A 6ag0A-4i59A:
undetectable		 6ag0A-4i59A:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC605_0
(ALPHA-AMYLASE)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		4 / 8 TYR A 459
GLY A 463
ILE A  41
HIS A  93
 FAD  A 501 (-4.4A)
FAD  A 501 ( 4.5A)
FAD  A 501 (-4.5A)
None
 0.95A 6ag0C-4i59A:
undetectable		 6ag0C-4i59A:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_0
(PROTEASE)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		5 / 12 GLY A  54
ALA A  55
VAL A  34
ILE A 474
VAL A  57
 None
 0.95A 6dh0A-4i59A:
undetectable		 6dh0A-4i59A:
9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IFT_A_SAMA301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)		 4i59 CYCLOHEXYLAMINE
OXIDASE
(Microbacterium
oxydans) 		5 / 12 ILE A  37
GLY A  38
GLY A  40
ALA A  45
VAL A 263
 FAD  A 501 (-4.7A)
FAD  A 501 (-3.2A)
FAD  A 501 (-3.5A)
None
FAD  A 501 (-3.9A)
 0.71A 6iftA-4i59A:
undetectable		 6iftA-4i59A:
21.02