SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4i6m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		4 / 8 THR B 169
GLY B 191
THR B 339
ILE B 194
 None
 0.81A 1c9sI-4i6mB:
undetectable
1c9sJ-4i6mB:
undetectable		 1c9sI-4i6mB:
11.93
1c9sJ-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 9 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.01A 1c9sL-4i6mB:
undetectable
1c9sM-4i6mB:
undetectable		 1c9sL-4i6mB:
11.93
1c9sM-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 9 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.02A 1c9sM-4i6mB:
undetectable
1c9sN-4i6mB:
undetectable		 1c9sM-4i6mB:
11.93
1c9sN-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 1c9sN-4i6mB:
undetectable
1c9sO-4i6mB:
undetectable		 1c9sN-4i6mB:
11.93
1c9sO-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 9 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.00A 1c9sO-4i6mB:
undetectable
1c9sP-4i6mB:
undetectable		 1c9sO-4i6mB:
11.93
1c9sP-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 11 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.01A 1c9sP-4i6mB:
undetectable
1c9sQ-4i6mB:
undetectable		 1c9sP-4i6mB:
11.93
1c9sQ-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 9 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 1c9sQ-4i6mB:
undetectable
1c9sR-4i6mB:
undetectable		 1c9sQ-4i6mB:
11.93
1c9sR-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 9 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.01A 1c9sS-4i6mB:
undetectable
1c9sT-4i6mB:
undetectable		 1c9sS-4i6mB:
11.93
1c9sT-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		4 / 7 GLY B 191
THR B 340
THR B 339
THR B 169
 None
 0.87A 1c9sT-4i6mB:
undetectable
1c9sU-4i6mB:
undetectable		 1c9sT-4i6mB:
11.93
1c9sU-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		4 / 8 GLY B 191
THR B 339
ILE B 194
THR B 169
 None
 0.80A 1c9sU-4i6mB:
undetectable
1c9sV-4i6mB:
undetectable		 1c9sU-4i6mB:
11.93
1c9sV-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 THR B 169
GLY B 191
THR B 340
THR B 339
ILE B 194
 None
 1.02A 1c9sL-4i6mB:
undetectable
1c9sV-4i6mB:
undetectable		 1c9sL-4i6mB:
11.93
1c9sV-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 4i6m ACTIN-RELATED
PROTEIN 7
(Saccharomyces
cerevisiae) 		3 / 3 TRP A 437
ARG A  88
THR A  17
 None
 0.99A 1df7A-4i6mA:
undetectable		 1df7A-4i6mA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 12 ILE B 428
PHE B 429
GLY B 431
SER B 436
LEU B  25
 None
 0.83A 1fm6X-4i6mB:
undetectable		 1fm6X-4i6mB:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_A_IPHA802_0
(PHENOL HYDROXYLASE)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 ASP B 163
GLY B 337
VAL B 336
ILE B 428
TYR B  13
 PO4  B 504 (-2.8A)
PO4  B 504 ( 3.8A)
None
None
None
 1.30A 1fohA-4i6mB:
undetectable		 1fohA-4i6mB:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_B_IPHB802_0
(PHENOL HYDROXYLASE)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 ASP B 163
GLY B 337
VAL B 336
ILE B 428
TYR B  13
 PO4  B 504 (-2.8A)
PO4  B 504 ( 3.8A)
None
None
None
 1.27A 1fohB-4i6mB:
undetectable		 1fohB-4i6mB:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_C_IPHC802_0
(PHENOL HYDROXYLASE)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 ASP B 163
GLY B 337
VAL B 336
ILE B 428
TYR B  13
 PO4  B 504 (-2.8A)
PO4  B 504 ( 3.8A)
None
None
None
 1.25A 1fohC-4i6mB:
undetectable		 1fohC-4i6mB:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 THR B 169
GLY B 191
THR B 340
THR B 339
ILE B 194
 None
 1.04A 1gtfH-4i6mB:
undetectable
1gtfI-4i6mB:
undetectable		 1gtfH-4i6mB:
11.93
1gtfI-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 9 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 1gtfO-4i6mB:
undetectable
1gtfP-4i6mB:
undetectable		 1gtfO-4i6mB:
11.93
1gtfP-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.05A 1gtfP-4i6mB:
undetectable
1gtfQ-4i6mB:
undetectable		 1gtfP-4i6mB:
11.93
1gtfQ-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 11 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 1gtfQ-4i6mB:
undetectable
1gtfR-4i6mB:
undetectable		 1gtfQ-4i6mB:
11.93
1gtfR-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 9 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.05A 1gtfR-4i6mB:
undetectable
1gtfS-4i6mB:
undetectable		 1gtfR-4i6mB:
11.93
1gtfS-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 11 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 1gtfS-4i6mB:
undetectable
1gtfT-4i6mB:
undetectable		 1gtfS-4i6mB:
11.93
1gtfT-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 1gtfT-4i6mB:
undetectable
1gtfU-4i6mB:
undetectable		 1gtfT-4i6mB:
11.93
1gtfU-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 11 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 1gtfU-4i6mB:
undetectable
1gtfV-4i6mB:
undetectable		 1gtfU-4i6mB:
11.93
1gtfV-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 THR B 169
GLY B 191
THR B 340
THR B 339
ILE B 194
 None
 1.04A 1gtfL-4i6mB:
undetectable
1gtfV-4i6mB:
undetectable		 1gtfL-4i6mB:
11.93
1gtfV-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		4 / 7 GLY B 191
THR B 339
ILE B 194
THR B 169
 None
 0.81A 1gtnA-4i6mB:
undetectable
1gtnK-4i6mB:
undetectable		 1gtnA-4i6mB:
11.93
1gtnK-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		4 / 7 THR B 169
GLY B 191
THR B 339
ILE B 194
 None
 0.82A 1gtnC-4i6mB:
undetectable
1gtnD-4i6mB:
undetectable		 1gtnC-4i6mB:
11.93
1gtnD-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		4 / 6 THR B 169
GLY B 191
THR B 339
ILE B 194
 None
 0.79A 1gtnD-4i6mB:
undetectable
1gtnE-4i6mB:
undetectable		 1gtnD-4i6mB:
11.93
1gtnE-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		4 / 6 THR B 169
GLY B 191
THR B 340
THR B 339
 None
 0.91A 1gtnD-4i6mB:
undetectable
1gtnE-4i6mB:
undetectable		 1gtnD-4i6mB:
11.93
1gtnE-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		4 / 7 THR B 169
GLY B 191
THR B 339
ILE B 194
 None
 0.79A 1gtnF-4i6mB:
undetectable
1gtnG-4i6mB:
undetectable		 1gtnF-4i6mB:
11.93
1gtnG-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		4 / 7 THR B 169
GLY B 191
THR B 340
THR B 339
 None
 0.91A 1gtnF-4i6mB:
undetectable
1gtnG-4i6mB:
undetectable		 1gtnF-4i6mB:
11.93
1gtnG-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		4 / 7 THR B 169
GLY B 191
THR B 339
ILE B 194
 None
 0.82A 1gtnJ-4i6mB:
undetectable
1gtnK-4i6mB:
undetectable		 1gtnJ-4i6mB:
11.93
1gtnK-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		4 / 7 THR B 169
GLY B 191
THR B 340
THR B 339
 None
 0.92A 1gtnJ-4i6mB:
undetectable
1gtnK-4i6mB:
undetectable		 1gtnJ-4i6mB:
11.93
1gtnK-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 9 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 1gtnL-4i6mB:
undetectable
1gtnM-4i6mB:
undetectable		 1gtnL-4i6mB:
11.93
1gtnM-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.02A 1gtnN-4i6mB:
undetectable
1gtnO-4i6mB:
undetectable		 1gtnN-4i6mB:
11.93
1gtnO-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 9 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.01A 1gtnR-4i6mB:
undetectable
1gtnS-4i6mB:
undetectable		 1gtnR-4i6mB:
11.93
1gtnS-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 9 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.00A 1gtnS-4i6mB:
undetectable
1gtnT-4i6mB:
undetectable		 1gtnS-4i6mB:
11.93
1gtnT-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.02A 1gtnU-4i6mB:
undetectable
1gtnV-4i6mB:
undetectable		 1gtnU-4i6mB:
11.93
1gtnV-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_A_IPHA6012_0
(PHENOL
2-MONOOXYGENASE)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 ASP B 163
GLY B 337
VAL B 336
ILE B 428
TYR B  13
 PO4  B 504 (-2.8A)
PO4  B 504 ( 3.8A)
None
None
None
 1.27A 1pn0A-4i6mB:
undetectable		 1pn0A-4i6mB:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_B_IPHB6022_0
(PHENOL
2-MONOOXYGENASE)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 ASP B 163
GLY B 337
VAL B 336
ILE B 428
TYR B  13
 PO4  B 504 (-2.8A)
PO4  B 504 ( 3.8A)
None
None
None
 1.27A 1pn0B-4i6mB:
undetectable		 1pn0B-4i6mB:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_C_IPHC6032_0
(PHENOL
2-MONOOXYGENASE)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 ASP B 163
GLY B 337
VAL B 336
ILE B 428
TYR B  13
 PO4  B 504 (-2.8A)
PO4  B 504 ( 3.8A)
None
None
None
 1.24A 1pn0C-4i6mB:
undetectable		 1pn0C-4i6mB:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_D_IPHD6042_0
(PHENOL
2-MONOOXYGENASE)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 ASP B 163
GLY B 337
VAL B 336
ILE B 428
TYR B  13
 PO4  B 504 (-2.8A)
PO4  B 504 ( 3.8A)
None
None
None
 1.24A 1pn0D-4i6mB:
undetectable		 1pn0D-4i6mB:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RV7_B_AB1B1001_1
(PROTEASE)		 4i6m ACTIN-RELATED
PROTEIN 7
(Saccharomyces
cerevisiae) 		5 / 11 ASN A  79
ALA A  82
ILE A  48
THR A  39
ALA A  45
 None
 1.02A 1rv7A-4i6mA:
undetectable
1rv7B-4i6mA:
undetectable		 1rv7A-4i6mA:
12.00
1rv7B-4i6mA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		4 / 8 GLY B 191
THR B 339
ILE B 194
THR B 169
 None
 0.81A 1utdI-4i6mB:
undetectable
1utdJ-4i6mB:
undetectable		 1utdI-4i6mB:
11.93
1utdJ-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 11 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 1utdM-4i6mB:
undetectable
1utdN-4i6mB:
undetectable		 1utdM-4i6mB:
11.93
1utdN-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.06A 1utdQ-4i6mB:
undetectable
1utdR-4i6mB:
undetectable		 1utdQ-4i6mB:
11.93
1utdR-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 1utdR-4i6mB:
undetectable
1utdS-4i6mB:
undetectable		 1utdR-4i6mB:
11.93
1utdS-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 11 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.06A 1utdS-4i6mB:
undetectable
1utdT-4i6mB:
undetectable		 1utdS-4i6mB:
11.93
1utdT-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 1utdT-4i6mB:
undetectable
1utdU-4i6mB:
undetectable		 1utdT-4i6mB:
11.93
1utdU-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 1utdU-4i6mB:
undetectable
1utdV-4i6mB:
undetectable		 1utdU-4i6mB:
11.93
1utdV-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 11 THR B 169
GLY B 191
THR B 340
THR B 339
ILE B 194
 None
 1.09A 1utdL-4i6mB:
undetectable
1utdV-4i6mB:
undetectable		 1utdL-4i6mB:
11.93
1utdV-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VIF_A_FOLA1_0
(DIHYDROFOLATE
REDUCTASE)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		3 / 3 GLN B  40
ILE B  41
TYR B  42
 None
 0.76A 1vifA-4i6mB:
undetectable		 1vifA-4i6mB:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC5_A_NCAA2001_0
(NAD-DEPENDENT
DEACETYLASE)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		4 / 7 ILE B  73
ASP B  75
ILE B 126
ASP B 123
 None
 0.90A 1yc5A-4i6mB:
undetectable		 1yc5A-4i6mB:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_F_SAMF301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4i6m ACTIN-RELATED
PROTEIN 7
ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		3 / 3 LYS A 433
ASP B 318
CYH B 403
 None
PO4  B 506 (-3.1A)
None
 1.48A 2br4F-4i6mA:
undetectable		 2br4F-4i6mA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 4i6m ACTIN-RELATED
PROTEIN 7
(Saccharomyces
cerevisiae) 		4 / 7 TYR A 123
GLU A 141
HIS A  11
GLY A 436
 None
PO4  A 505 (-3.3A)
PO4  A 505 (-4.2A)
PO4  A 505 ( 4.8A)
 1.27A 2ha4B-4i6mA:
undetectable		 2ha4B-4i6mA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMA_A_SAMA375_0
(PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE)		 4i6m ACTIN-RELATED
PROTEIN 7
(Saccharomyces
cerevisiae) 		5 / 11 GLY A  75
SER A 162
SER A  14
GLY A  13
HIS A  11
 PO4  A 506 ( 3.8A)
PO4  A 506 (-2.8A)
PO4  A 506 (-2.9A)
PO4  A 505 (-3.5A)
PO4  A 505 (-4.2A)
 1.45A 2hmaA-4i6mA:
undetectable		 2hmaA-4i6mA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 4i6m ACTIN-RELATED
PROTEIN 7
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 446
PRO A 447
LEU A 451
 None
 0.31A 2qd5B-4i6mA:
2.6		 2qd5B-4i6mA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		4 / 5 GLN B 129
PHE B 132
LEU B  83
PHE B  79
 None
 1.25A 3ablC-4i6mB:
undetectable
3ablJ-4i6mB:
undetectable		 3ablC-4i6mB:
18.30
3ablJ-4i6mB:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		4 / 6 THR B  31
PHE B  30
GLN B 433
LEU B  25
 None
 0.91A 3bgdA-4i6mB:
undetectable		 3bgdA-4i6mB:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 4i6m ACTIN-RELATED
PROTEIN 7
(Saccharomyces
cerevisiae) 		4 / 4 SER A 397
GLY A 396
GLY A 186
GLY A 163
 PO4  A 503 (-2.2A)
None
PO4  A 503 (-3.1A)
None
 0.84A 3bogB-4i6mA:
undetectable
3bogD-4i6mA:
undetectable		 3bogB-4i6mA:
undetectable
3bogD-4i6mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 12 GLY B 165
ASP B 163
HIS B 117
GLN B 179
ASN B  70
 PO4  B 501 ( 3.8A)
PO4  B 504 (-2.8A)
None
None
PO4  B 501 (-4.6A)
 1.20A 3eeyJ-4i6mB:
undetectable		 3eeyJ-4i6mB:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 4i6m ACTIN-LIKE PROTEIN
ARP9
ACTIN-RELATED
PROTEIN 7
(Saccharomyces
cerevisiae) 		4 / 6 ILE A 145
ALA A 146
ALA C 612
THR A 442
 None
 1.05A 3mdrB-4i6mA:
undetectable		 3mdrB-4i6mA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		4 / 8 GLY B 351
LEU B 353
LEU B 354
ILE B 407
 None
 0.91A 3nbqB-4i6mB:
undetectable		 3nbqB-4i6mB:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		4 / 5 ILE B  37
THR B  19
THR B  18
PHE B  82
 None
 0.91A 3snfA-4i6mB:
undetectable		 3snfA-4i6mB:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYE_B_YTZB902_1
(DIHYDROPTEROATE
SYNTHASE)		 4i6m ACTIN-RELATED
PROTEIN 7
(Saccharomyces
cerevisiae) 		3 / 3 PHE A 323
LYS A 183
SER A 182
 None
 1.02A 3tyeB-4i6mA:
undetectable		 3tyeB-4i6mA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_0
(PUTATIVE REGULATORY
PROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		5 / 12 LEU B 143
ILE B 439
SER B 436
ALA B 178
PHE C 629
 None
 1.19A 3vw1D-4i6mB:
undetectable		 3vw1D-4i6mB:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4i6m ACTIN-RELATED
PROTEIN 7
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 446
PRO A 447
LEU A 451
 None
 0.47A 3w1wB-4i6mA:
2.8		 3w1wB-4i6mA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 4i6m ACTIN-RELATED
PROTEIN 7
(Saccharomyces
cerevisiae) 		5 / 11 ILE A 157
ASP A 158
ILE A 159
GLY A 396
VAL A 238
 None
PO4  A 506 (-3.9A)
None
None
None
 1.11A 4ac9B-4i6mA:
2.5
4ac9C-4i6mA:
undetectable		 4ac9B-4i6mA:
20.76
4ac9C-4i6mA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_B_ACTB701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 4i6m ACTIN-LIKE PROTEIN
ARP9
ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		3 / 3 HIS C 637
GLY B 431
ILE B 434
 None
 0.59A 4k50A-4i6mC:
undetectable		 4k50A-4i6mC:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_J_ACTJ701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 4i6m ACTIN-LIKE PROTEIN
ARP9
ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		3 / 3 HIS C 637
GLY B 431
ILE B 434
 None
 0.58A 4k50I-4i6mC:
undetectable		 4k50I-4i6mC:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		 4i6m ACTIN-RELATED
PROTEIN 7
(Saccharomyces
cerevisiae) 		4 / 7 LEU A  95
VAL A  97
PRO A  99
TYR A  89
 None
 1.09A 4lb2A-4i6mA:
undetectable		 4lb2A-4i6mA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_1
(PROTEASE)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 12 ILE B 335
VAL B 329
VAL B 164
ILE B 309
THR B 340
 None
 0.90A 4q5mA-4i6mB:
undetectable		 4q5mA-4i6mB:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4i6m ACTIN-RELATED
PROTEIN 7
(Saccharomyces
cerevisiae) 		4 / 8 VAL A   8
LEU A 104
ILE A  10
PHE A 128
 None
 0.65A 4r38A-4i6mA:
undetectable		 4r38A-4i6mA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4i6m ACTIN-RELATED
PROTEIN 7
(Saccharomyces
cerevisiae) 		4 / 7 GLU A 141
ILE A 393
LEU A 387
ILE A 169
 PO4  A 505 (-3.3A)
None
None
None
 0.92A 4xumA-4i6mA:
undetectable		 4xumA-4i6mA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5eeuN-4i6mB:
undetectable
5eeuO-4i6mB:
undetectable		 5eeuN-4i6mB:
11.93
5eeuO-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 5eeuO-4i6mB:
undetectable
5eeuP-4i6mB:
undetectable		 5eeuO-4i6mB:
11.93
5eeuP-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 5eeuP-4i6mB:
undetectable
5eeuQ-4i6mB:
undetectable		 5eeuP-4i6mB:
11.93
5eeuQ-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5eeuQ-4i6mB:
undetectable
5eeuR-4i6mB:
undetectable		 5eeuQ-4i6mB:
11.93
5eeuR-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.02A 5eeuR-4i6mB:
undetectable
5eeuS-4i6mB:
undetectable		 5eeuR-4i6mB:
11.93
5eeuS-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.05A 5eeuT-4i6mB:
undetectable
5eeuU-4i6mB:
undetectable		 5eeuT-4i6mB:
11.93
5eeuU-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5eeuU-4i6mB:
undetectable
5eeuV-4i6mB:
undetectable		 5eeuU-4i6mB:
11.93
5eeuV-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5eevN-4i6mB:
undetectable
5eevO-4i6mB:
undetectable		 5eevN-4i6mB:
11.93
5eevO-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5eevO-4i6mB:
undetectable
5eevP-4i6mB:
undetectable		 5eevO-4i6mB:
11.93
5eevP-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 5eevP-4i6mB:
undetectable
5eevQ-4i6mB:
undetectable		 5eevP-4i6mB:
11.93
5eevQ-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5eevQ-4i6mB:
undetectable
5eevR-4i6mB:
undetectable		 5eevQ-4i6mB:
11.93
5eevR-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.02A 5eevR-4i6mB:
undetectable
5eevS-4i6mB:
undetectable		 5eevR-4i6mB:
11.93
5eevS-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.05A 5eevT-4i6mB:
undetectable
5eevU-4i6mB:
undetectable		 5eevT-4i6mB:
11.93
5eevU-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5eevU-4i6mB:
undetectable
5eevV-4i6mB:
undetectable		 5eevU-4i6mB:
11.93
5eevV-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5eewN-4i6mB:
undetectable
5eewO-4i6mB:
undetectable		 5eewN-4i6mB:
11.93
5eewO-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5eewO-4i6mB:
undetectable
5eewP-4i6mB:
undetectable		 5eewO-4i6mB:
11.93
5eewP-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 5eewP-4i6mB:
undetectable
5eewQ-4i6mB:
undetectable		 5eewP-4i6mB:
11.93
5eewQ-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5eewQ-4i6mB:
undetectable
5eewR-4i6mB:
undetectable		 5eewQ-4i6mB:
11.93
5eewR-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.02A 5eewR-4i6mB:
undetectable
5eewS-4i6mB:
undetectable		 5eewR-4i6mB:
11.93
5eewS-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5eewT-4i6mB:
undetectable
5eewU-4i6mB:
undetectable		 5eewT-4i6mB:
11.93
5eewU-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5eewU-4i6mB:
undetectable
5eewV-4i6mB:
undetectable		 5eewU-4i6mB:
11.93
5eewV-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5eexN-4i6mB:
undetectable
5eexO-4i6mB:
undetectable		 5eexN-4i6mB:
11.93
5eexO-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5eexO-4i6mB:
undetectable
5eexP-4i6mB:
undetectable		 5eexO-4i6mB:
11.93
5eexP-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 5eexP-4i6mB:
undetectable
5eexQ-4i6mB:
undetectable		 5eexP-4i6mB:
11.93
5eexQ-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 9 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5eexQ-4i6mB:
undetectable
5eexR-4i6mB:
undetectable		 5eexQ-4i6mB:
11.93
5eexR-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 5eexR-4i6mB:
undetectable
5eexS-4i6mB:
undetectable		 5eexR-4i6mB:
11.93
5eexS-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.05A 5eexT-4i6mB:
undetectable
5eexU-4i6mB:
undetectable		 5eexT-4i6mB:
11.93
5eexU-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5eexU-4i6mB:
undetectable
5eexV-4i6mB:
undetectable		 5eexU-4i6mB:
11.93
5eexV-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5eeyN-4i6mB:
undetectable
5eeyO-4i6mB:
undetectable		 5eeyN-4i6mB:
11.93
5eeyO-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5eeyO-4i6mB:
undetectable
5eeyP-4i6mB:
undetectable		 5eeyO-4i6mB:
11.93
5eeyP-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 5eeyP-4i6mB:
undetectable
5eeyQ-4i6mB:
undetectable		 5eeyP-4i6mB:
11.93
5eeyQ-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 9 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5eeyQ-4i6mB:
undetectable
5eeyR-4i6mB:
undetectable		 5eeyQ-4i6mB:
11.93
5eeyR-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 5eeyR-4i6mB:
undetectable
5eeyS-4i6mB:
undetectable		 5eeyR-4i6mB:
11.93
5eeyS-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.05A 5eeyT-4i6mB:
undetectable
5eeyU-4i6mB:
undetectable		 5eeyT-4i6mB:
11.93
5eeyU-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5eeyU-4i6mB:
undetectable
5eeyV-4i6mB:
undetectable		 5eeyU-4i6mB:
11.93
5eeyV-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5eezN-4i6mB:
undetectable
5eezO-4i6mB:
undetectable		 5eezN-4i6mB:
11.93
5eezO-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5eezO-4i6mB:
undetectable
5eezP-4i6mB:
undetectable		 5eezO-4i6mB:
11.93
5eezP-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 5eezP-4i6mB:
undetectable
5eezQ-4i6mB:
undetectable		 5eezP-4i6mB:
11.93
5eezQ-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 9 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.05A 5eezQ-4i6mB:
undetectable
5eezR-4i6mB:
undetectable		 5eezQ-4i6mB:
11.93
5eezR-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.02A 5eezR-4i6mB:
undetectable
5eezS-4i6mB:
undetectable		 5eezR-4i6mB:
11.93
5eezS-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.05A 5eezT-4i6mB:
undetectable
5eezU-4i6mB:
undetectable		 5eezT-4i6mB:
11.93
5eezU-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5eezU-4i6mB:
undetectable
5eezV-4i6mB:
undetectable		 5eezU-4i6mB:
11.93
5eezV-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5ef0N-4i6mB:
undetectable
5ef0O-4i6mB:
undetectable		 5ef0N-4i6mB:
11.93
5ef0O-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5ef0O-4i6mB:
undetectable
5ef0P-4i6mB:
undetectable		 5ef0O-4i6mB:
11.93
5ef0P-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 5ef0P-4i6mB:
undetectable
5ef0Q-4i6mB:
undetectable		 5ef0P-4i6mB:
11.93
5ef0Q-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 9 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5ef0Q-4i6mB:
undetectable
5ef0R-4i6mB:
undetectable		 5ef0Q-4i6mB:
11.93
5ef0R-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 5ef0R-4i6mB:
undetectable
5ef0S-4i6mB:
undetectable		 5ef0R-4i6mB:
11.93
5ef0S-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.05A 5ef0T-4i6mB:
undetectable
5ef0U-4i6mB:
undetectable		 5ef0T-4i6mB:
11.93
5ef0U-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5ef0U-4i6mB:
undetectable
5ef0V-4i6mB:
undetectable		 5ef0U-4i6mB:
11.93
5ef0V-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5ef1N-4i6mB:
undetectable
5ef1O-4i6mB:
undetectable		 5ef1N-4i6mB:
11.93
5ef1O-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5ef1O-4i6mB:
undetectable
5ef1P-4i6mB:
undetectable		 5ef1O-4i6mB:
11.93
5ef1P-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 5ef1P-4i6mB:
undetectable
5ef1Q-4i6mB:
undetectable		 5ef1P-4i6mB:
11.93
5ef1Q-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 9 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.05A 5ef1Q-4i6mB:
undetectable
5ef1R-4i6mB:
undetectable		 5ef1Q-4i6mB:
11.93
5ef1R-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 5ef1R-4i6mB:
undetectable
5ef1S-4i6mB:
undetectable		 5ef1R-4i6mB:
11.93
5ef1S-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.05A 5ef1T-4i6mB:
undetectable
5ef1U-4i6mB:
undetectable		 5ef1T-4i6mB:
11.93
5ef1U-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5ef1U-4i6mB:
undetectable
5ef1V-4i6mB:
undetectable		 5ef1U-4i6mB:
11.93
5ef1V-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5ef2N-4i6mB:
undetectable
5ef2O-4i6mB:
undetectable		 5ef2N-4i6mB:
11.93
5ef2O-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5ef2O-4i6mB:
undetectable
5ef2P-4i6mB:
undetectable		 5ef2O-4i6mB:
11.93
5ef2P-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 5ef2P-4i6mB:
undetectable
5ef2Q-4i6mB:
undetectable		 5ef2P-4i6mB:
11.93
5ef2Q-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 9 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.05A 5ef2Q-4i6mB:
undetectable
5ef2R-4i6mB:
undetectable		 5ef2Q-4i6mB:
11.93
5ef2R-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 5ef2R-4i6mB:
undetectable
5ef2S-4i6mB:
undetectable		 5ef2R-4i6mB:
11.93
5ef2S-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.05A 5ef2T-4i6mB:
undetectable
5ef2U-4i6mB:
undetectable		 5ef2T-4i6mB:
11.93
5ef2U-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5ef2U-4i6mB:
undetectable
5ef2V-4i6mB:
undetectable		 5ef2U-4i6mB:
11.93
5ef2V-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.05A 5ef3N-4i6mB:
undetectable
5ef3O-4i6mB:
undetectable		 5ef3N-4i6mB:
11.93
5ef3O-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5ef3O-4i6mB:
undetectable
5ef3P-4i6mB:
undetectable		 5ef3O-4i6mB:
11.93
5ef3P-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 5ef3P-4i6mB:
undetectable
5ef3Q-4i6mB:
undetectable		 5ef3P-4i6mB:
11.93
5ef3Q-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 9 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.05A 5ef3Q-4i6mB:
undetectable
5ef3R-4i6mB:
undetectable		 5ef3Q-4i6mB:
11.93
5ef3R-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.03A 5ef3R-4i6mB:
undetectable
5ef3S-4i6mB:
undetectable		 5ef3R-4i6mB:
11.93
5ef3S-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.05A 5ef3T-4i6mB:
undetectable
5ef3U-4i6mB:
undetectable		 5ef3T-4i6mB:
11.93
5ef3U-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 GLY B 191
THR B 340
THR B 339
ILE B 194
THR B 169
 None
 1.04A 5ef3U-4i6mB:
undetectable
5ef3V-4i6mB:
undetectable		 5ef3U-4i6mB:
11.93
5ef3V-4i6mB:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ENT_C_MIYC901_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB)		 4i6m ACTIN-RELATED
PROTEIN 7
(Saccharomyces
cerevisiae) 		5 / 9 SER A 182
GLY A 396
SER A 397
ILE A 394
ALA A 425
 None
None
PO4  A 503 (-2.2A)
None
None
 1.41A 5entC-4i6mA:
undetectable		 5entC-4i6mA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_C_REAC602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 10 ILE B 194
GLY B 190
THR B 169
LEU B 305
PHE B 219
 None
 1.10A 5fhzC-4i6mB:
undetectable		 5fhzC-4i6mB:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI6_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		5 / 12 LEU B  35
SER B  89
ILE B  90
LEU B  10
THR B  18
 None
 1.13A 5hi6B-4i6mB:
undetectable		 5hi6B-4i6mB:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4i6m ACTIN-RELATED
PROTEIN 7
ACTIN-LIKE PROTEIN
ARP9
REGULATOR OF TY1
TRANSPOSITION
PROTEIN 102
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		3 / 3 LEU A 102
TYR D  27
SER B 122
 None
 0.60A 5iktA-4i6mA:
undetectable		 5iktA-4i6mA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 4i6m ACTIN-RELATED
PROTEIN 7
(Saccharomyces
cerevisiae) 		5 / 12 VAL A  71
ASP A  72
SER A  33
THR A 395
GLY A 163
 None
 1.46A 5m50B-4i6mA:
undetectable		 5m50B-4i6mA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		4 / 6 ASP B 163
ASP B 170
HIS B 168
HIS B 116
 PO4  B 504 (-2.8A)
None
PO4  B 501 (-3.9A)
None
 0.87A 5nelA-4i6mB:
undetectable
5nelD-4i6mB:
undetectable		 5nelA-4i6mB:
18.65
5nelD-4i6mB:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PHH_A_LDPA414_1
(LYSINE-SPECIFIC
DEMETHYLASE 4D)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		4 / 6 GLU B 347
ALA B 348
LEU B 350
SER B 223
 None
 1.04A 5phhA-4i6mB:
undetectable		 5phhA-4i6mB:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		4 / 7 ALA B 149
THR B 150
ILE B 162
VAL B 336
 None
 0.94A 6cduF-4i6mB:
undetectable
6cduJ-4i6mB:
undetectable		 6cduF-4i6mB:
22.62
6cduJ-4i6mB:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		4 / 5 ARG C 632
ALA C 635
GLN B 438
ILE B 434
 None
 1.38A 6f6sA-4i6mC:
undetectable
6f6sB-4i6mC:
undetectable		 6f6sA-4i6mC:
23.01
6f6sB-4i6mC:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 4i6m ACTIN-LIKE PROTEIN
ARP9
(Saccharomyces
cerevisiae) 		3 / 3 TYR B 177
ASP B 176
GLN B 157
 None
 0.95A 6g1pA-4i6mB:
undetectable		 6g1pA-4i6mB:
21.56