SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4i7a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)		 4i7a ETHANOLAMINE
UTILIZATION PROTEIN
EUTN/CARBOXYSOME
STRUCTURAL PROTEIN
CCML
(Rhodospirillum
rubrum) 		5 / 9 ILE A  81
LEU A  30
VAL A   6
GLY A  52
ALA A  49
 None
 1.14A 1e7aA-4i7aA:
undetectable		 1e7aA-4i7aA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4003_1
(SERUM ALBUMIN)		 4i7a ETHANOLAMINE
UTILIZATION PROTEIN
EUTN/CARBOXYSOME
STRUCTURAL PROTEIN
CCML
(Rhodospirillum
rubrum) 		5 / 9 ILE A  81
LEU A  30
VAL A   6
GLY A  52
ALA A  49
 None
 1.12A 1e7bA-4i7aA:
undetectable		 1e7bA-4i7aA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 4i7a ETHANOLAMINE
UTILIZATION PROTEIN
EUTN/CARBOXYSOME
STRUCTURAL PROTEIN
CCML
(Rhodospirillum
rubrum) 		5 / 10 VAL A   6
GLY A  50
VAL A  42
ASN A  51
GLY A   8
 None
 1.26A 3km6A-4i7aA:
undetectable		 3km6A-4i7aA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 4i7a ETHANOLAMINE
UTILIZATION PROTEIN
EUTN/CARBOXYSOME
STRUCTURAL PROTEIN
CCML
(Rhodospirillum
rubrum) 		5 / 9 VAL A   6
GLY A  50
VAL A  42
ASN A  51
GLY A   8
 None
 1.27A 3kmoA-4i7aA:
undetectable		 3kmoA-4i7aA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)		 4i7a ETHANOLAMINE
UTILIZATION PROTEIN
EUTN/CARBOXYSOME
STRUCTURAL PROTEIN
CCML
(Rhodospirillum
rubrum) 		4 / 6 THR A  46
GLY A  48
ILE A  81
LEU A  25
 None
 1.05A 4ac9C-4i7aA:
undetectable		 4ac9C-4i7aA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4i7a ETHANOLAMINE
UTILIZATION PROTEIN
EUTN/CARBOXYSOME
STRUCTURAL PROTEIN
CCML
(Rhodospirillum
rubrum) 		4 / 6 THR A  46
GLY A  48
ILE A  81
LEU A  25
 None
 1.05A 4acaC-4i7aA:
undetectable		 4acaC-4i7aA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4i7a ETHANOLAMINE
UTILIZATION PROTEIN
EUTN/CARBOXYSOME
STRUCTURAL PROTEIN
CCML
(Rhodospirillum
rubrum) 		4 / 6 THR A  46
GLY A  48
ILE A  81
LEU A  25
 None
 1.06A 4acbC-4i7aA:
undetectable		 4acbC-4i7aA:
11.83