SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4i7h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_1
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 8 TYR A  37
TYR A  51
LEU A  63
SER A  46
 None
 0.91A 1i7zA-4i7hA:
undetectable		 1i7zA-4i7hA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  19
GLU A  22
HIS A   6
HIS A   4
 NI  A 201 (-3.5A)
None
NI  A 201 (-3.6A)
NI  A 201 (-3.6A)
 1.18A 1uttA-4i7hA:
undetectable		 1uttA-4i7hA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  19
GLU A  22
HIS A   6
HIS A   4
 NI  A 201 (-3.5A)
None
NI  A 201 (-3.6A)
NI  A 201 (-3.6A)
 1.16A 1utzA-4i7hA:
undetectable		 1utzA-4i7hA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  19
GLU A  22
HIS A   6
HIS A   4
 NI  A 201 (-3.5A)
None
NI  A 201 (-3.6A)
NI  A 201 (-3.6A)
 1.18A 1utzB-4i7hA:
undetectable		 1utzB-4i7hA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		3 / 3 ILE A 139
ASP A 112
PHE A 113
 None
 0.56A 1uwjB-4i7hA:
undetectable		 1uwjB-4i7hA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_E_NCAE509_0
(NAD-DEPENDENT
DEACETYLASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 6 ASP A  75
GLU A  81
TYR A  92
LYS A  71
 None
 1.44A 1yc2A-4i7hA:
undetectable
1yc2B-4i7hA:
undetectable
1yc2E-4i7hA:
undetectable		 1yc2A-4i7hA:
22.44
1yc2B-4i7hA:
22.44
1yc2E-4i7hA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  99
HIS A   6
HIS A  19
HIS A  97
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 1.28A 2fqeA-4i7hA:
undetectable		 2fqeA-4i7hA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A   6
HIS A  99
HIS A  97
HIS A  19
 NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
 1.38A 2fqfA-4i7hA:
undetectable		 2fqfA-4i7hA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  99
HIS A   6
HIS A  19
HIS A  97
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 1.27A 2fqfA-4i7hA:
undetectable		 2fqfA-4i7hA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A   6
HIS A  99
HIS A  97
HIS A  19
 NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
 1.34A 2fqgA-4i7hA:
undetectable		 2fqgA-4i7hA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  99
HIS A   6
HIS A  19
HIS A  97
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 1.22A 2fqgA-4i7hA:
undetectable		 2fqgA-4i7hA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  19
GLU A  22
HIS A   6
HIS A   4
 NI  A 201 (-3.5A)
None
NI  A 201 (-3.6A)
NI  A 201 (-3.6A)
 1.17A 2hu6A-4i7hA:
undetectable		 2hu6A-4i7hA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  19
GLU A  22
HIS A   6
HIS A   4
 NI  A 201 (-3.5A)
None
NI  A 201 (-3.6A)
NI  A 201 (-3.6A)
 1.13A 2ow9B-4i7hA:
undetectable		 2ow9B-4i7hA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  19
GLU A  22
HIS A   6
HIS A   4
 NI  A 201 (-3.5A)
None
NI  A 201 (-3.6A)
NI  A 201 (-3.6A)
 1.15A 2ozrC-4i7hA:
undetectable		 2ozrC-4i7hA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  19
GLU A  22
HIS A   6
HIS A   4
 NI  A 201 (-3.5A)
None
NI  A 201 (-3.6A)
NI  A 201 (-3.6A)
 1.15A 2ozrD-4i7hA:
undetectable		 2ozrD-4i7hA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  19
GLU A  22
HIS A   6
HIS A   4
 NI  A 201 (-3.5A)
None
NI  A 201 (-3.6A)
NI  A 201 (-3.6A)
 1.23A 2ozrE-4i7hA:
undetectable		 2ozrE-4i7hA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		5 / 12 HIS A   4
HIS A  19
GLY A  96
HIS A  97
HIS A  99
 NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
None
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
 1.16A 2pgrA-4i7hA:
undetectable		 2pgrA-4i7hA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A   6
HIS A   4
HIS A  99
HIS A  19
 NI  A 201 (-3.6A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.5A)
 1.09A 2wkoA-4i7hA:
undetectable		 2wkoA-4i7hA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  19
GLU A  22
HIS A   6
HIS A   4
 NI  A 201 (-3.5A)
None
NI  A 201 (-3.6A)
NI  A 201 (-3.6A)
 1.17A 3lilA-4i7hA:
undetectable		 3lilA-4i7hA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA604_0
(LACCASE-1)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  99
HIS A   6
HIS A  19
HIS A  97
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 1.26A 3qpkA-4i7hA:
undetectable		 3qpkA-4i7hA:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB604_0
(LACCASE-1)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A   6
HIS A  99
HIS A  97
HIS A  19
 NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
 1.35A 3qpkB-4i7hA:
undetectable		 3qpkB-4i7hA:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB604_0
(LACCASE-1)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  99
HIS A   6
HIS A  19
HIS A  97
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 1.22A 3qpkB-4i7hA:
undetectable		 3qpkB-4i7hA:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1003_0
(BLUE COPPER OXIDASE
CUEO)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		5 / 5 HIS A   6
HIS A  99
HIS A  19
HIS A   4
HIS A  97
 NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.6A)
 1.29A 4ef3A-4i7hA:
undetectable		 4ef3A-4i7hA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1004_0
(BLUE COPPER OXIDASE
CUEO)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A   6
HIS A  99
HIS A  97
HIS A  19
 NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
 1.36A 4ef3A-4i7hA:
undetectable		 4ef3A-4i7hA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1004_0
(BLUE COPPER OXIDASE
CUEO)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  99
HIS A   6
HIS A  19
HIS A  97
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 1.24A 4ef3A-4i7hA:
undetectable		 4ef3A-4i7hA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA503_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A   6
HIS A  99
HIS A  97
HIS A  19
 NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
 1.32A 5mejA-4i7hA:
undetectable		 5mejA-4i7hA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA503_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  99
HIS A   6
HIS A  19
HIS A  97
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 1.17A 5mejA-4i7hA:
undetectable		 5mejA-4i7hA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA503_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A   6
HIS A  99
HIS A  97
HIS A  19
 NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
 1.32A 5mewA-4i7hA:
undetectable		 5mewA-4i7hA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA503_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  99
HIS A   6
HIS A  19
HIS A  97
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 1.18A 5mewA-4i7hA:
undetectable		 5mewA-4i7hA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA503_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A   6
HIS A  99
HIS A  97
HIS A  19
 NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
 1.32A 5mhuA-4i7hA:
undetectable		 5mhuA-4i7hA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA503_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  99
HIS A   6
HIS A  19
HIS A  97
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 1.18A 5mhuA-4i7hA:
undetectable		 5mhuA-4i7hA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA503_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A   6
HIS A  99
HIS A  97
HIS A  19
 NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
 1.32A 5mhvA-4i7hA:
undetectable		 5mhvA-4i7hA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA503_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  99
HIS A   6
HIS A  19
HIS A  97
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 1.18A 5mhvA-4i7hA:
undetectable		 5mhvA-4i7hA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A   6
HIS A  99
HIS A  97
HIS A  19
 NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
 1.32A 5mhwA-4i7hA:
undetectable		 5mhwA-4i7hA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  99
HIS A   6
HIS A  19
HIS A  97
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 1.18A 5mhwA-4i7hA:
undetectable		 5mhwA-4i7hA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A   6
HIS A  99
HIS A  97
HIS A  19
 NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
 1.31A 5mhxA-4i7hA:
undetectable		 5mhxA-4i7hA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  99
HIS A   6
HIS A  19
HIS A  97
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 1.18A 5mhxA-4i7hA:
undetectable		 5mhxA-4i7hA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A   6
HIS A  99
HIS A  97
HIS A  19
 NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
 1.31A 5mhyA-4i7hA:
undetectable		 5mhyA-4i7hA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  99
HIS A   6
HIS A  19
HIS A  97
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 1.18A 5mhyA-4i7hA:
undetectable		 5mhyA-4i7hA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A   6
HIS A  99
HIS A  97
HIS A  19
 NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
 1.32A 5mhzA-4i7hA:
undetectable		 5mhzA-4i7hA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  99
HIS A   6
HIS A  19
HIS A  97
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 1.18A 5mhzA-4i7hA:
undetectable		 5mhzA-4i7hA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A   6
HIS A  99
HIS A  97
HIS A  19
 NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
 1.31A 5mi1A-4i7hA:
undetectable		 5mi1A-4i7hA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  99
HIS A   6
HIS A  19
HIS A  97
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 1.18A 5mi1A-4i7hA:
undetectable		 5mi1A-4i7hA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA603_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A   6
HIS A  99
HIS A  97
HIS A  19
 NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
 1.31A 5mi2A-4i7hA:
undetectable		 5mi2A-4i7hA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA603_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  99
HIS A   6
HIS A  19
HIS A  97
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 1.17A 5mi2A-4i7hA:
undetectable		 5mi2A-4i7hA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA603_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A   6
HIS A  99
HIS A  97
HIS A  19
 NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
 1.31A 5miaA-4i7hA:
undetectable		 5miaA-4i7hA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA603_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  99
HIS A   6
HIS A  19
HIS A  97
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 1.18A 5miaA-4i7hA:
undetectable		 5miaA-4i7hA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA603_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A   6
HIS A  99
HIS A  97
HIS A  19
 NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
 1.31A 5mibA-4i7hA:
undetectable		 5mibA-4i7hA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA603_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  99
HIS A   6
HIS A  19
HIS A  97
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 1.18A 5mibA-4i7hA:
undetectable		 5mibA-4i7hA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA603_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A   6
HIS A  99
HIS A  97
HIS A  19
 NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
 1.31A 5micA-4i7hA:
undetectable		 5micA-4i7hA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA603_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  99
HIS A   6
HIS A  19
HIS A  97
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 1.17A 5micA-4i7hA:
undetectable		 5micA-4i7hA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA603_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A   6
HIS A  99
HIS A  97
HIS A  19
 NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
 1.31A 5midA-4i7hA:
undetectable		 5midA-4i7hA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA603_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  99
HIS A   6
HIS A  19
HIS A  97
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 1.18A 5midA-4i7hA:
undetectable		 5midA-4i7hA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA603_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A   6
HIS A  99
HIS A  97
HIS A  19
 NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
 1.31A 5mieA-4i7hA:
undetectable		 5mieA-4i7hA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA603_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  99
HIS A   6
HIS A  19
HIS A  97
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 1.18A 5mieA-4i7hA:
undetectable		 5mieA-4i7hA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA603_0
(LACCASE 2)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  99
HIS A   6
HIS A  19
HIS A  97
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 1.17A 5migA-4i7hA:
undetectable		 5migA-4i7hA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A  19
GLU A  22
HIS A   6
HIS A   4
 NI  A 201 (-3.5A)
None
NI  A 201 (-3.6A)
NI  A 201 (-3.6A)
 1.17A 5n5jA-4i7hA:
undetectable		 5n5jA-4i7hA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIH_A_8CVA201_1
(DIHYDROFOLATE
REDUCTASE)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 8 ILE A  39
ASP A  11
LEU A  10
ILE A  35
 None
 0.91A 5uihA-4i7hA:
undetectable		 5uihA-4i7hA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 5 HIS A   4
HIS A  97
HIS A  99
HIS A   6
 NI  A 201 (-3.6A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 0.85A 5zrdB-4i7hA:
undetectable		 5zrdB-4i7hA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 5 HIS A  19
HIS A   4
HIS A  97
PHE A  78
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.6A)
None
 0.97A 5zrdB-4i7hA:
undetectable		 5zrdB-4i7hA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A   4
HIS A  97
HIS A  99
HIS A   6
 NI  A 201 (-3.6A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 0.81A 5zrdC-4i7hA:
undetectable		 5zrdC-4i7hA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A   4
HIS A  99
HIS A   6
HIS A  19
 NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
 1.12A 5zrdC-4i7hA:
undetectable		 5zrdC-4i7hA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 5 HIS A  19
HIS A   4
HIS A  97
PHE A  78
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.6A)
None
 0.99A 5zrdC-4i7hA:
undetectable		 5zrdC-4i7hA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 5 HIS A  19
HIS A   4
HIS A  97
PHE A  78
 NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.6A)
None
 0.98A 5zrdD-4i7hA:
undetectable		 5zrdD-4i7hA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A   4
HIS A  97
HIS A  99
HIS A   6
 NI  A 201 (-3.6A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
 0.84A 5zrdD-4i7hA:
undetectable		 5zrdD-4i7hA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 4i7h PEROXIDE STRESS
SENSING REGULATOR
(Streptococcus
pyogenes) 		4 / 4 HIS A   4
HIS A  99
HIS A   6
HIS A  19
 NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
NI  A 201 (-3.6A)
NI  A 201 (-3.5A)
 1.12A 5zrdD-4i7hA:
undetectable		 5zrdD-4i7hA:
16.55