SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4i7l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4i7l LYSOZYME
(Escherichia
virus
T4) 		5 / 12 ALA A 129
PHE A 153
LEU A 133
ALA A 130
ILE A  78
 None
IPH  A 202 (-4.4A)
None
BME  A 210 ( 4.3A)
IPH  A 202 ( 4.5A)
 1.00A 2aclA-4i7lA:
undetectable
2aclE-4i7lA:
undetectable		 2aclA-4i7lA:
21.05
2aclE-4i7lA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4i7l LYSOZYME
(Escherichia
virus
T4) 		4 / 6 PHE A 153
VAL A  87
LEU A 118
ALA A 129
 IPH  A 202 (-4.4A)
IPH  A 202 ( 4.4A)
None
None
 1.02A 2e1qC-4i7lA:
undetectable		 2e1qC-4i7lA:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_D_TC9D1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4i7l LYSOZYME
(Escherichia
virus
T4) 		4 / 8 THR A  34
TYR A  25
ILE A  17
SER A  36
 None
 1.08A 2xytE-4i7lA:
undetectable		 2xytE-4i7lA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4i7l LYSOZYME
(Escherichia
virus
T4) 		4 / 8 THR A  34
TYR A  25
ILE A  17
SER A  36
 None
 1.03A 2xytH-4i7lA:
undetectable		 2xytH-4i7lA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4i7l LYSOZYME
(Escherichia
virus
T4) 		4 / 7 THR A  34
TYR A  25
ILE A  17
SER A  36
 None
 1.05A 2xytI-4i7lA:
undetectable		 2xytI-4i7lA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4i7l LYSOZYME
(Escherichia
virus
T4) 		4 / 8 PHE A 153
VAL A  87
LEU A 118
ALA A 129
 IPH  A 202 (-4.4A)
IPH  A 202 ( 4.4A)
None
None
 1.02A 3ax7A-4i7lA:
undetectable		 3ax7A-4i7lA:
9.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4i7l LYSOZYME
(Escherichia
virus
T4) 		4 / 6 THR A  34
TYR A  25
ILE A  17
SER A  36
 None
 1.27A 3peoG-4i7lA:
undetectable		 3peoG-4i7lA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KSZ_A_CYSA620_0
(LACTOPEROXIDASE)		 4i7l LYSOZYME
(Escherichia
virus
T4) 		3 / 3 ARG A   8
GLU A  11
PHE A 104
 None
 0.87A 4kszA-4i7lA:
undetectable		 4kszA-4i7lA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4i7l LYSOZYME
(Escherichia
virus
T4) 		4 / 7 THR A  26
TYR A  18
GLU A  11
HIS A  31
 None
 0.99A 5ecnA-4i7lA:
undetectable		 5ecnA-4i7lA:
17.23