SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4i86'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4i86 CELLULOSE SYNTHASE 1
(Komagataeibacter
xylinus) 		4 / 7 PHE A  80
THR A  51
LEU A  47
VAL A  25
 None
 0.99A 1t87A-4i86A:
undetectable		 1t87A-4i86A:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)		 4i86 CELLULOSE SYNTHASE 1
(Komagataeibacter
xylinus) 		4 / 8 ASP A  60
LEU A 100
LEU A  59
SER A  92
 None
 1.00A 3lm8B-4i86A:
undetectable
3lm8D-4i86A:
undetectable		 3lm8B-4i86A:
21.65
3lm8D-4i86A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 4i86 CELLULOSE SYNTHASE 1
(Komagataeibacter
xylinus) 		4 / 7 PHE A  80
THR A  51
LEU A  47
VAL A  25
 None
 0.94A 3wrmF-4i86A:
undetectable		 3wrmF-4i86A:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4i86 CELLULOSE SYNTHASE 1
(Komagataeibacter
xylinus) 		4 / 7 PHE A  80
THR A  51
LEU A  47
VAL A  25
 None
 0.98A 4l4gA-4i86A:
undetectable		 4l4gA-4i86A:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V01_A_0LIA1776_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4i86 CELLULOSE SYNTHASE 1
(Komagataeibacter
xylinus) 		6 / 12 GLU A  30
ILE A  12
ALA A  68
LEU A 100
ALA A  37
ASP A  31
 None
 1.35A 4v01A-4i86A:
undetectable		 4v01A-4i86A:
16.50