SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4i8q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 10 GLY A 364
ALA A 353
THR A 379
ILE A 360
GLY A 397
 None
 0.95A 1c9sN-4i8qA:
undetectable
1c9sO-4i8qA:
undetectable		 1c9sN-4i8qA:
9.01
1c9sO-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 11 GLY A 364
ALA A 353
THR A 379
ILE A 360
GLY A 397
 None
 0.95A 1c9sP-4i8qA:
undetectable
1c9sQ-4i8qA:
undetectable		 1c9sP-4i8qA:
9.01
1c9sQ-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 9 GLY A 364
ALA A 353
THR A 379
ILE A 360
GLY A 397
 None
 0.93A 1c9sQ-4i8qA:
undetectable
1c9sR-4i8qA:
undetectable		 1c9sQ-4i8qA:
9.01
1c9sR-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 10 GLY A 397
GLY A 364
ALA A 353
THR A 379
ILE A 360
 None
 0.94A 1c9sL-4i8qA:
undetectable
1c9sV-4i8qA:
undetectable		 1c9sL-4i8qA:
9.01
1c9sV-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_1
(TRANSTHYRETIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		4 / 7 LEU A 184
LEU A 157
SER A 235
THR A 237
 None
None
None
NAD  A 601 (-4.2A)
 0.68A 1dvxA-4i8qA:
undetectable		 1dvxA-4i8qA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		4 / 7 LEU A 184
LEU A 157
SER A 235
THR A 237
 None
None
None
NAD  A 601 (-4.2A)
 0.70A 1dvxB-4i8qA:
undetectable		 1dvxB-4i8qA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4001_1
(SERUM ALBUMIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		4 / 5 ARG A  63
ALA A  62
ASP A  65
GLY A  67
 None
 0.95A 1e7bA-4i8qA:
undetectable		 1e7bA-4i8qA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4001_1
(SERUM ALBUMIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		4 / 5 ARG A  63
ALA A  62
ASP A  65
GLY A  67
 None
 1.00A 1e7cA-4i8qA:
undetectable		 1e7cA-4i8qA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 9 GLY A 397
GLY A 364
ALA A 353
THR A 379
ILE A 360
 None
 0.90A 1gtfD-4i8qA:
undetectable
1gtfE-4i8qA:
undetectable		 1gtfD-4i8qA:
9.01
1gtfE-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 10 GLY A 397
GLY A 364
ALA A 353
THR A 379
ILE A 360
 None
 0.89A 1gtfJ-4i8qA:
undetectable
1gtfK-4i8qA:
undetectable		 1gtfJ-4i8qA:
9.01
1gtfK-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 11 GLY A 364
ALA A 353
THR A 379
ILE A 360
GLY A 397
 None
 0.95A 1gtfQ-4i8qA:
undetectable
1gtfR-4i8qA:
undetectable		 1gtfQ-4i8qA:
9.01
1gtfR-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 9 GLY A 364
ALA A 353
THR A 379
ILE A 360
GLY A 397
 None
 0.95A 1gtfR-4i8qA:
undetectable
1gtfS-4i8qA:
undetectable		 1gtfR-4i8qA:
9.01
1gtfS-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 11 GLY A 364
ALA A 353
THR A 379
ILE A 360
GLY A 397
 None
 0.95A 1gtfS-4i8qA:
undetectable
1gtfT-4i8qA:
undetectable		 1gtfS-4i8qA:
9.01
1gtfT-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 11 GLY A 364
ALA A 353
THR A 379
ILE A 360
GLY A 397
 None
 0.92A 1gtnT-4i8qA:
undetectable
1gtnU-4i8qA:
undetectable		 1gtnT-4i8qA:
9.01
1gtnU-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 12 GLY A 397
GLY A 364
ALA A 353
THR A 379
ILE A 360
 None
 0.95A 1gtnL-4i8qA:
undetectable
1gtnV-4i8qA:
undetectable		 1gtnL-4i8qA:
9.01
1gtnV-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		4 / 6 LEU A 184
LEU A 157
SER A 235
THR A 237
 None
None
None
NAD  A 601 (-4.2A)
 0.90A 1ictB-4i8qA:
undetectable		 1ictB-4i8qA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_2
(TRANSTHYRETIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		4 / 7 LEU A 184
LEU A 157
SER A 235
THR A 237
 None
None
None
NAD  A 601 (-4.2A)
 0.81A 1ictD-4i8qA:
undetectable		 1ictD-4i8qA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		4 / 6 LEU A 184
LEU A 157
SER A 235
THR A 237
 None
None
None
NAD  A 601 (-4.2A)
 0.75A 1tyrA-4i8qA:
undetectable		 1tyrA-4i8qA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 10 GLY A 364
ALA A 353
THR A 379
ILE A 360
GLY A 397
 None
 0.91A 1utdE-4i8qA:
undetectable
1utdF-4i8qA:
undetectable		 1utdE-4i8qA:
9.01
1utdF-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 10 GLY A 364
ALA A 353
THR A 379
ILE A 360
GLY A 397
 None
 0.87A 1utdH-4i8qA:
undetectable
1utdI-4i8qA:
undetectable		 1utdH-4i8qA:
9.01
1utdI-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 12 GLY A 364
ALA A 353
THR A 379
ILE A 360
GLY A 397
 None
 0.94A 1utdL-4i8qA:
undetectable
1utdM-4i8qA:
undetectable		 1utdL-4i8qA:
9.01
1utdM-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 12 GLY A 364
ALA A 353
THR A 379
ILE A 360
GLY A 397
 None
 0.93A 1utdO-4i8qA:
undetectable
1utdP-4i8qA:
undetectable		 1utdO-4i8qA:
9.01
1utdP-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 11 GLY A 364
ALA A 353
THR A 379
ILE A 360
GLY A 397
 None
 0.90A 1utdP-4i8qA:
undetectable
1utdQ-4i8qA:
undetectable		 1utdP-4i8qA:
9.01
1utdQ-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 11 GLY A 364
ALA A 353
THR A 379
ILE A 360
GLY A 397
 None
 0.92A 1utdS-4i8qA:
undetectable
1utdT-4i8qA:
undetectable		 1utdS-4i8qA:
9.01
1utdT-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 10 GLY A 364
ALA A 353
THR A 379
ILE A 360
GLY A 397
 None
 0.95A 1utdU-4i8qA:
undetectable
1utdV-4i8qA:
undetectable		 1utdU-4i8qA:
9.01
1utdV-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 11 GLY A 397
GLY A 364
ALA A 353
THR A 379
ILE A 360
 None
 0.94A 1utdL-4i8qA:
undetectable
1utdV-4i8qA:
undetectable		 1utdL-4i8qA:
9.01
1utdV-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_B_TACB1888_1
(ELONGATION FACTOR
EF-TU)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		4 / 5 SER A 107
ASP A 110
PRO A 164
SER A  97
 None
 1.49A 2hdnA-4i8qA:
undetectable
2hdnB-4i8qA:
undetectable
2hdnD-4i8qA:
undetectable		 2hdnA-4i8qA:
6.73
2hdnB-4i8qA:
22.82
2hdnD-4i8qA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_D_TACD2888_1
(ELONGATION FACTOR
EF-TU)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		4 / 5 SER A  97
SER A 107
ASP A 110
PRO A 164
 None
 1.47A 2hdnB-4i8qA:
undetectable
2hdnC-4i8qA:
undetectable
2hdnD-4i8qA:
undetectable		 2hdnB-4i8qA:
22.82
2hdnC-4i8qA:
6.73
2hdnD-4i8qA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMA_A_SAMA375_0
(PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 11 GLY A 462
SER A 466
ASN A 416
THR A 443
GLY A 423
 None
 1.49A 2hmaA-4i8qA:
2.0		 2hmaA-4i8qA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB501_1
(CYTOCHROME P450 2C8)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 9 GLY A 156
ILE A 213
VAL A 172
ILE A 169
VAL A 114
 None
 1.19A 2nnhB-4i8qA:
undetectable		 2nnhB-4i8qA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_A_SAMA201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 12 GLY A 179
ALA A 178
LEU A 211
VAL A  54
LEU A 225
 None
 0.98A 2nyuA-4i8qA:
3.1		 2nyuA-4i8qA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		4 / 6 VAL A 269
PHE A 441
PRO A 266
THR A 298
 None
 1.21A 2q6oB-4i8qA:
undetectable		 2q6oB-4i8qA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3V_A_TOPA1169_1
(DIHYDROFOLATE
REDUCTASE)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 12 TRP A 282
ALA A 279
ILE A 273
ILE A 448
THR A 283
 None
 1.14A 2w3vA-4i8qA:
undetectable		 2w3vA-4i8qA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 12 LEU A 166
VAL A 114
THR A 237
PHE A 480
ASN A 479
 None
None
NAD  A 601 (-4.2A)
None
None
 1.36A 2y00B-4i8qA:
undetectable		 2y00B-4i8qA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 12 LEU A 166
VAL A 114
THR A 237
PHE A 480
ASN A 479
 None
None
NAD  A 601 (-4.2A)
None
None
 1.32A 2y01B-4i8qA:
undetectable		 2y01B-4i8qA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		4 / 7 ARG A  63
ALA A 210
ASN A 212
ALA A 181
 None
 1.01A 2zgwA-4i8qA:
undetectable		 2zgwA-4i8qA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		3 / 3 THR A 242
SER A 187
LYS A 185
 NAD  A 601 (-2.8A)
NAD  A 601 (-3.5A)
NAD  A 601 (-2.7A)
 1.16A 3aocC-4i8qA:
undetectable		 3aocC-4i8qA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH504_3
(PHOSPHOLIPASE A2)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 11 VAL A 426
LYS A 264
SER A 265
PRO A 266
SER A 299
 None
 1.30A 3bjwH-4i8qA:
undetectable		 3bjwH-4i8qA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_A_DIFA1_1
(TRANSTHYRETIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		4 / 6 LEU A 184
LEU A 157
SER A 235
THR A 237
 None
None
None
NAD  A 601 (-4.2A)
 0.81A 3cfqA-4i8qA:
undetectable		 3cfqA-4i8qA:
12.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_A_VORA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 9 LEU A  92
SER A 107
ILE A 192
ALA A 190
ALA A 168
 None
 1.29A 3mdtA-4i8qA:
undetectable		 3mdtA-4i8qA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		4 / 7 LEU A 184
LEU A 157
SER A 235
THR A 237
 None
None
None
NAD  A 601 (-4.2A)
 0.87A 3ozkB-4i8qA:
undetectable		 3ozkB-4i8qA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 12 GLY A 216
PRO A 224
GLY A 222
ASN A  26
ASP A  41
 None
None
NAD  A 601 (-3.7A)
None
None
 1.44A 3r24A-4i8qA:
undetectable		 3r24A-4i8qA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FR8_A_TNGA601_1
(ALDEHYDE
DEHYDROGENASE,
MITOCHONDRIAL)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 11 ASN A 162
LEU A 166
MET A 167
TRP A 170
SER A 296
 NAD  A 601 (-3.3A)
None
NAD  A 601 ( 3.9A)
EDO  A 609 (-4.2A)
None
 0.50A 4fr8A-4i8qA:
54.9		 4fr8A-4i8qA:
38.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_B_ECNB403_1
(FLAVOHEMOGLOBIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 11 ILE A 213
ALA A 210
LEU A 211
VAL A 172
LEU A 197
 None
 1.07A 4g1bB-4i8qA:
undetectable		 4g1bB-4i8qA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		4 / 6 LEU A 184
LEU A 157
SER A 235
THR A 237
 None
None
None
NAD  A 601 (-4.2A)
 0.82A 4i89A-4i8qA:
undetectable		 4i89A-4i8qA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_B_IMNB201_1
(TRANSTHYRETIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		4 / 6 LEU A 184
LEU A 157
SER A 235
THR A 237
 None
None
None
NAD  A 601 (-4.2A)
 0.94A 4ikiB-4i8qA:
undetectable		 4ikiB-4i8qA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		4 / 7 LEU A 184
LEU A 157
SER A 235
THR A 237
 None
None
None
NAD  A 601 (-4.2A)
 0.90A 4iklA-4i8qA:
undetectable
4iklB-4i8qA:
undetectable		 4iklA-4i8qA:
12.90
4iklB-4i8qA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		4 / 8 LEU A 184
LEU A 157
SER A 235
THR A 237
 None
None
None
NAD  A 601 (-4.2A)
 0.93A 4iklA-4i8qA:
undetectable
4iklB-4i8qA:
undetectable		 4iklA-4i8qA:
12.90
4iklB-4i8qA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		3 / 3 GLY A 335
PRO A 336
GLN A 293
 None
 0.32A 4oltB-4i8qA:
undetectable		 4oltB-4i8qA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		4 / 7 LEU A 184
LEU A 157
SER A 235
THR A 237
 None
None
None
NAD  A 601 (-4.2A)
 0.79A 4pwjB-4i8qA:
undetectable		 4pwjB-4i8qA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		3 / 3 GLY A 335
PRO A 336
GLN A 293
 None
 0.28A 4qwpB-4i8qA:
undetectable		 4qwpB-4i8qA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		3 / 3 GLU A 119
ILE A 200
ALA A 173
 None
 0.63A 4wnwB-4i8qA:
undetectable		 4wnwB-4i8qA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		3 / 3 SER A 265
ALA A 425
VAL A 426
 None
 0.60A 4x1iA-4i8qA:
undetectable		 4x1iA-4i8qA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		4 / 6 LEU A 184
LEU A 157
SER A 235
THR A 237
 None
None
None
NAD  A 601 (-4.2A)
 0.76A 5bojA-4i8qA:
undetectable		 5bojA-4i8qA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		6 / 12 PRO A 207
GLY A  17
SER A 208
GLY A 209
LEU A 211
LEU A 195
 None
 1.18A 5c0oH-4i8qA:
3.9		 5c0oH-4i8qA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 10 GLY A 397
GLY A 364
ALA A 353
THR A 379
ILE A 360
 None
 0.92A 5eevA-4i8qA:
undetectable
5eevB-4i8qA:
undetectable		 5eevA-4i8qA:
9.01
5eevB-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 10 GLY A 397
GLY A 364
ALA A 353
THR A 379
ILE A 360
 None
 0.92A 5eewA-4i8qA:
undetectable
5eewB-4i8qA:
undetectable		 5eewA-4i8qA:
9.01
5eewB-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 10 GLY A 397
GLY A 364
ALA A 353
THR A 379
ILE A 360
 None
 0.92A 5eexA-4i8qA:
undetectable
5eexB-4i8qA:
undetectable		 5eexA-4i8qA:
9.01
5eexB-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 10 GLY A 397
GLY A 364
ALA A 353
THR A 379
ILE A 360
 None
 0.92A 5eeyA-4i8qA:
undetectable
5eeyB-4i8qA:
undetectable		 5eeyA-4i8qA:
9.01
5eeyB-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 10 GLY A 397
GLY A 364
ALA A 353
THR A 379
ILE A 360
 None
 0.92A 5eezA-4i8qA:
undetectable
5eezB-4i8qA:
undetectable		 5eezA-4i8qA:
9.01
5eezB-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 10 GLY A 397
GLY A 364
ALA A 353
THR A 379
ILE A 360
 None
 0.92A 5ef0A-4i8qA:
undetectable
5ef0B-4i8qA:
undetectable		 5ef0A-4i8qA:
9.01
5ef0B-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 10 GLY A 397
GLY A 364
ALA A 353
THR A 379
ILE A 360
 None
 0.92A 5ef1A-4i8qA:
undetectable
5ef1B-4i8qA:
undetectable		 5ef1A-4i8qA:
9.01
5ef1B-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 10 GLY A 397
GLY A 364
ALA A 353
THR A 379
ILE A 360
 None
 0.92A 5ef2A-4i8qA:
undetectable
5ef2B-4i8qA:
undetectable		 5ef2A-4i8qA:
9.01
5ef2B-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 10 GLY A 397
GLY A 364
ALA A 353
THR A 379
ILE A 360
 None
 0.92A 5ef3A-4i8qA:
undetectable
5ef3B-4i8qA:
undetectable		 5ef3A-4i8qA:
9.01
5ef3B-4i8qA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_B_SAMB303_1
(CATECHOL
O-METHYLTRANSFERASE)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		4 / 5 SER A 258
SER A 296
GLN A 452
ASP A 471
 None
 1.36A 5fhrB-4i8qA:
4.2		 5fhrB-4i8qA:
18.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FHZ_A_REAA602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 12 ASN A 162
LEU A 166
MET A 167
TRP A 170
CYH A 295
 NAD  A 601 (-3.3A)
None
NAD  A 601 ( 3.9A)
EDO  A 609 (-4.2A)
NAD  A 601 (-3.3A)
 0.53A 5fhzA-4i8qA:
52.6		 5fhzA-4i8qA:
37.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G08_A_Z80A1187_1
(FREQUENIN 2)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		4 / 6 ILE A 287
PHE A 285
PHE A 396
TRP A 161
 None
None
NAD  A 601 (-3.9A)
NAD  A 601 (-3.9A)
 1.08A 5g08A-4i8qA:
undetectable		 5g08A-4i8qA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 12 VAL A 155
ASP A 232
LEU A 206
ALA A 175
PRO A 151
 None
 0.97A 5hnzB-4i8qA:
undetectable		 5hnzB-4i8qA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 12 LEU A 124
ASP A 129
GLY A  71
LEU A  78
ALA A 173
 None
 1.11A 5kbwA-4i8qA:
undetectable		 5kbwA-4i8qA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		3 / 3 ARG A  79
ILE A  81
PHE A 118
 None
 0.74A 5kirA-4i8qA:
undetectable		 5kirA-4i8qA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		4 / 6 LEU A 184
LEU A 157
SER A 235
THR A 237
 None
None
None
NAD  A 601 (-4.2A)
 0.76A 5l4iA-4i8qA:
undetectable		 5l4iA-4i8qA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND2_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 12 VAL A 155
ASP A 232
LEU A 206
ALA A 175
PRO A 151
 None
 1.19A 5nd2B-4i8qA:
2.2		 5nd2B-4i8qA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 12 VAL A 155
ASP A 232
LEU A 206
ALA A 175
PRO A 151
 None
 1.18A 5syfB-4i8qA:
undetectable		 5syfB-4i8qA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		4 / 8 GLY A 263
SER A 265
ASN A 162
VAL A 294
 None
None
NAD  A 601 (-3.3A)
None
 0.93A 6giqL-4i8qA:
undetectable
6giqP-4i8qA:
undetectable
6giqT-4i8qA:
undetectable		 6giqL-4i8qA:
21.85
6giqP-4i8qA:
17.67
6giqT-4i8qA:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 11 GLY A 263
SER A 265
ALA A 424
ASN A 162
VAL A 294
 None
None
None
NAD  A 601 (-3.3A)
None
 1.28A 6hu9A-4i8qA:
0.8
6hu9E-4i8qA:
undetectable
6hu9I-4i8qA:
undetectable		 6hu9A-4i8qA:
22.11
6hu9E-4i8qA:
16.88
6hu9I-4i8qA:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 11 MET A 167
GLY A 263
SER A 265
ALA A 424
VAL A 294
 NAD  A 601 ( 3.9A)
None
None
None
None
 1.45A 6hu9A-4i8qA:
0.8
6hu9E-4i8qA:
undetectable
6hu9I-4i8qA:
undetectable		 6hu9A-4i8qA:
22.11
6hu9E-4i8qA:
16.88
6hu9I-4i8qA:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 10 GLY A 263
SER A 265
ALA A 424
ASN A 162
VAL A 294
 None
None
None
NAD  A 601 (-3.3A)
None
 1.22A 6hu9L-4i8qA:
undetectable
6hu9P-4i8qA:
undetectable
6hu9T-4i8qA:
undetectable		 6hu9L-4i8qA:
22.11
6hu9P-4i8qA:
16.88
6hu9T-4i8qA:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 4i8q PUTATIVE BETAINE
ALDEHYDE
DEHYROGENASE
(Solanum
lycopersicum) 		5 / 10 MET A 167
GLY A 263
SER A 265
ALA A 424
VAL A 294
 NAD  A 601 ( 3.9A)
None
None
None
None
 1.44A 6hu9L-4i8qA:
undetectable
6hu9P-4i8qA:
undetectable
6hu9T-4i8qA:
undetectable		 6hu9L-4i8qA:
22.11
6hu9P-4i8qA:
16.88
6hu9T-4i8qA:
7.78