SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4i9f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		4 / 7 LEU A 263
ARG A 303
ASP A 297
GLY A 251
 None
 0.61A 1n13D-4i9fA:
undetectable
1n13E-4i9fA:
undetectable		 1n13D-4i9fA:
14.40
1n13E-4i9fA:
8.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		4 / 7 ILE A  93
LEU A  99
ARG A 109
LEU A  81
 None
 0.94A 1v54N-4i9fA:
undetectable
1v54W-4i9fA:
undetectable		 1v54N-4i9fA:
20.93
1v54W-4i9fA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		4 / 7 ILE A  93
LEU A  99
ARG A 109
LEU A  81
 None
 0.88A 2dyrN-4i9fA:
undetectable
2dyrW-4i9fA:
undetectable		 2dyrN-4i9fA:
20.93
2dyrW-4i9fA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		4 / 6 ASP A 212
ARG A 210
ASP A 209
ASP A 153
 None
None
CA  A 401 (-2.7A)
None
 1.28A 2j2pE-4i9fA:
undetectable
2j2pF-4i9fA:
undetectable		 2j2pE-4i9fA:
18.73
2j2pF-4i9fA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_A_SAMA500_0
(HYPOTHETICAL PROTEIN)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		4 / 7 VAL A 283
ALA A 331
PRO A 268
TRP A 272
 None
 1.02A 2q6oA-4i9fA:
undetectable		 2q6oA-4i9fA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		4 / 7 ILE A  93
LEU A  99
ARG A 109
LEU A  81
 None
 0.91A 3ablA-4i9fA:
undetectable
3ablJ-4i9fA:
undetectable		 3ablA-4i9fA:
20.93
3ablJ-4i9fA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		4 / 8 ILE A  93
LEU A  99
ARG A 109
LEU A  81
 None
 0.93A 3ablN-4i9fA:
undetectable
3ablW-4i9fA:
undetectable		 3ablN-4i9fA:
20.93
3ablW-4i9fA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		4 / 7 ILE A  93
LEU A  99
ARG A 109
LEU A  81
 None
 0.90A 3ag3A-4i9fA:
undetectable
3ag3J-4i9fA:
undetectable		 3ag3A-4i9fA:
20.93
3ag3J-4i9fA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		4 / 8 ILE A  93
LEU A  99
ARG A 109
LEU A  81
 None
 0.93A 3ag3N-4i9fA:
undetectable
3ag3W-4i9fA:
undetectable		 3ag3N-4i9fA:
20.93
3ag3W-4i9fA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		4 / 8 ILE A  93
LEU A  99
ARG A 109
LEU A  81
 None
 0.93A 3asnN-4i9fA:
undetectable
3asnW-4i9fA:
undetectable		 3asnN-4i9fA:
20.93
3asnW-4i9fA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		3 / 3 ARG A 210
ASP A 237
ASP A 212
 None
 0.75A 3jayA-4i9fA:
1.8		 3jayA-4i9fA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		3 / 3 ARG A 210
ASP A 237
ASP A 212
 None
 0.89A 3jb2A-4i9fA:
undetectable		 3jb2A-4i9fA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		3 / 3 VAL A 207
VAL A  36
SER A  32
 None
 0.74A 3n8xB-4i9fA:
undetectable		 3n8xB-4i9fA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		4 / 7 ILE A  93
LEU A  99
ARG A  90
LEU A  81
 None
 0.89A 5b1bA-4i9fA:
undetectable
5b1bJ-4i9fA:
undetectable		 5b1bA-4i9fA:
20.93
5b1bJ-4i9fA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		4 / 7 ILE A  93
LEU A  99
ARG A 109
LEU A  81
 None
 0.95A 5b1bA-4i9fA:
undetectable
5b1bJ-4i9fA:
undetectable		 5b1bA-4i9fA:
20.93
5b1bJ-4i9fA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_2
(ESTROGEN RECEPTOR)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		4 / 6 LEU A 254
LEU A 264
LEU A 205
HIS A 258
 None
 0.86A 5gs4A-4i9fA:
undetectable		 5gs4A-4i9fA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_2
(ESTROGEN RECEPTOR)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		4 / 5 LEU A 254
LEU A 264
LEU A 205
HIS A 258
 None
 0.99A 5gtrA-4i9fA:
undetectable		 5gtrA-4i9fA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		4 / 7 ILE A  93
LEU A  99
ARG A 109
LEU A  81
 None
 0.93A 5iy5A-4i9fA:
undetectable
5iy5J-4i9fA:
undetectable		 5iy5A-4i9fA:
20.93
5iy5J-4i9fA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		5 / 10 PRO A  25
ILE A  13
LEU A  61
VAL A  30
PHE A  42
 None
 1.45A 5tixB-4i9fA:
undetectable		 5tixB-4i9fA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_1
(RIBOFLAVIN LYASE)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		5 / 12 ALA A 221
ALA A 190
GLY A 185
GLY A 208
VAL A  43
 None
 0.90A 5w4zA-4i9fA:
undetectable		 5w4zA-4i9fA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_B_RBFB502_1
(RIBOFLAVIN LYASE)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		5 / 12 ALA A 221
ALA A 190
GLY A 185
GLY A 208
VAL A  43
 None
 0.90A 5w4zB-4i9fA:
undetectable		 5w4zB-4i9fA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		4 / 7 ILE A  93
LEU A  99
ARG A  90
LEU A  81
 None
 0.89A 5xdqN-4i9fA:
undetectable
5xdqW-4i9fA:
undetectable		 5xdqN-4i9fA:
20.93
5xdqW-4i9fA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		4 / 7 ILE A  93
LEU A  99
ARG A 109
LEU A  81
 None
 0.84A 5xdqN-4i9fA:
undetectable
5xdqW-4i9fA:
undetectable		 5xdqN-4i9fA:
20.93
5xdqW-4i9fA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		4 / 8 ILE A  93
LEU A  99
ARG A 109
LEU A  81
 None
 0.83A 5xdxN-4i9fA:
undetectable
5xdxW-4i9fA:
undetectable		 5xdxN-4i9fA:
20.93
5xdxW-4i9fA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4i9f GLYCEROL 3-PHOSPHATE
PHOSPHATASE
(Mycobacterium
tuberculosis) 		4 / 7 ILE A  93
LEU A  99
ARG A 109
LEU A  81
 None
 0.95A 6nmfA-4i9fA:
undetectable
6nmfJ-4i9fA:
undetectable		 6nmfA-4i9fA:
20.93
6nmfJ-4i9fA:
11.28