SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4i9o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDK_A_C2FA1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 4i9o CREB-BINDING PROTEIN
(Mus
musculus) 		5 / 11 TYR A 650
HIS A 592
TYR A 649
LEU A 599
HIS A 602
 None
 1.35A 2idkA-4i9oA:
undetectable
2idkB-4i9oA:
undetectable
2idkC-4i9oA:
undetectable
2idkD-4i9oA:
undetectable		 2idkA-4i9oA:
16.48
2idkB-4i9oA:
16.48
2idkC-4i9oA:
16.48
2idkD-4i9oA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_D_C2FD1200_0
(GLYCINE
N-METHYLTRANSFERASE)		 4i9o CREB-BINDING PROTEIN
(Mus
musculus) 		5 / 12 LEU A 599
HIS A 602
TYR A 649
HIS A 592
TYR A 650
 None
 1.32A 3thrA-4i9oA:
undetectable
3thrB-4i9oA:
undetectable
3thrC-4i9oA:
undetectable
3thrD-4i9oA:
undetectable		 3thrA-4i9oA:
16.79
3thrB-4i9oA:
16.79
3thrC-4i9oA:
16.79
3thrD-4i9oA:
16.79