SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4iab'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_H_SPMH202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4iab HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		4 / 6 ASN A  93
GLU A 118
TYR A  95
GLU A 116
 None
 1.48A 4r87H-4iabA:
undetectable		 4r87H-4iabA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 4iab HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		3 / 3 GLU A 146
TYR A  95
GLU A  97
 UNL  A 201 ( 2.9A)
None
UNL  A 201 ( 2.9A)
 0.67A 4ryaA-4iabA:
undetectable		 4ryaA-4iabA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 4iab HYPOTHETICAL PROTEIN
(Bacteroides
uniformis) 		4 / 6 ASN A 102
ASN A 113
ILE A  99
GLU A  97
 UNL  A 201 ( 3.5A)
UNL  A 201 ( 3.9A)
UNL  A 201 ( 4.9A)
UNL  A 201 ( 2.9A)
 1.18A 6h7uA-4iabA:
undetectable		 6h7uA-4iabA:
14.55