SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4iau'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 4iau BETA-GAMMA-CRYSTALLI
N
(Geodia
cydonium) 		4 / 5 LEU A 156
LEU A  88
LEU A 117
MET A 159
 None
 1.08A 2oaxF-4iauA:
undetectable		 2oaxF-4iauA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4iau BETA-GAMMA-CRYSTALLI
N
(Geodia
cydonium) 		4 / 4 ASN A 153
SER A 115
ALA A 146
VAL A 151
 GOL  A 801 (-3.3A)
None
None
None
 1.02A 4x1kC-4iauA:
undetectable		 4x1kC-4iauA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 4iau BETA-GAMMA-CRYSTALLI
N
(Geodia
cydonium) 		5 / 12 LEU A 101
LEU A 156
ALA A 116
ILE A 118
ALA A  86
 None
 0.99A 5eypB-4iauA:
undetectable		 5eypB-4iauA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_2
(TUBULIN BETA-2B
CHAIN)		 4iau BETA-GAMMA-CRYSTALLI
N
(Geodia
cydonium) 		5 / 12 LEU A 101
LEU A 156
ALA A 116
ILE A 118
ALA A  86
 None
 0.97A 5nm5B-4iauA:
undetectable		 5nm5B-4iauA:
15.70