SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ibn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_B_DVAB6_0
(GRAMICIDIN A)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		4 / 4 VAL A 213
TRP A 116
ALA A 112
VAL A 214
 None
 1.39A 1gmkA-4ibnA:
undetectable
1gmkB-4ibnA:
undetectable		 1gmkA-4ibnA:
10.53
1gmkB-4ibnA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2201_1
(PROTEIN (METHIONINE
REPRESSOR))		 4ibn RIBONUCLEASE H
(uncultured
organism) 		4 / 4 HIS A  84
ALA A  81
PHE A  79
GLY A  83
 None
 1.43A 1mj2B-4ibnA:
undetectable		 1mj2B-4ibnA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_0
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 12 SER A 178
LEU A  41
SER A 172
VAL A  58
ILE A  82
 None
 1.46A 1uobA-4ibnA:
undetectable		 1uobA-4ibnA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_D_SALD5006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		4 / 5 ARG A  88
THR A  14
LEU A  16
ALA A 140
 None
 1.45A 2e1qD-4ibnA:
undetectable		 2e1qD-4ibnA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		3 / 3 TRP A 111
VAL A 136
ARG A  88
 None
 0.98A 3b0wA-4ibnA:
undetectable		 3b0wA-4ibnA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS201_1
(PROTEIN S100-A4)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		4 / 7 PHE A  93
PHE A  79
GLY A  39
MET A 104
 None
 1.11A 3ko0K-4ibnA:
undetectable
3ko0S-4ibnA:
undetectable		 3ko0K-4ibnA:
16.82
3ko0S-4ibnA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA802_0
(GLUTAMATE RECEPTOR 2)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		3 / 3 ASP A  22
ASN A 155
SER A  24
 None
 0.83A 3lslA-4ibnA:
undetectable
3lslD-4ibnA:
undetectable		 3lslA-4ibnA:
21.74
3lslD-4ibnA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		3 / 3 SER A  24
ASP A  22
ASN A 155
 None
 0.83A 3lslA-4ibnA:
undetectable
3lslD-4ibnA:
undetectable		 3lslA-4ibnA:
21.74
3lslD-4ibnA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_C_PXLC400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 12 ASP A  57
SER A 178
LEU A 161
GLN A 154
TYR A  20
 None
 1.49A 3mbhC-4ibnA:
undetectable		 3mbhC-4ibnA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 12 THR A  95
THR A  94
GLY A  39
ALA A 158
HIS A 152
 None
 1.19A 3mg02-4ibnA:
undetectable
3mg0V-4ibnA:
undetectable		 3mg02-4ibnA:
19.20
3mg0V-4ibnA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OF4_B_ACTB313_0
(NITROREDUCTASE)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		3 / 3 ALA A 215
VAL A 214
GLN A 130
 None
 0.73A 3of4B-4ibnA:
undetectable		 3of4B-4ibnA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.19A 4qvlV-4ibnA:
undetectable
4qvlb-4ibnA:
undetectable		 4qvlV-4ibnA:
21.18
4qvlb-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.19A 4qvlH-4ibnA:
undetectable
4qvlN-4ibnA:
undetectable		 4qvlH-4ibnA:
21.18
4qvlN-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.20A 4qvmV-4ibnA:
undetectable
4qvmb-4ibnA:
undetectable		 4qvmV-4ibnA:
21.18
4qvmb-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.20A 4qvmH-4ibnA:
undetectable
4qvmN-4ibnA:
undetectable		 4qvmH-4ibnA:
21.18
4qvmN-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 12 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.20A 4qvnV-4ibnA:
undetectable
4qvnb-4ibnA:
undetectable		 4qvnV-4ibnA:
21.18
4qvnb-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 12 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.19A 4qvnH-4ibnA:
undetectable
4qvnN-4ibnA:
undetectable		 4qvnH-4ibnA:
21.18
4qvnN-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.20A 4qvpV-4ibnA:
undetectable
4qvpb-4ibnA:
undetectable		 4qvpV-4ibnA:
21.18
4qvpb-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.20A 4qvpH-4ibnA:
undetectable
4qvpN-4ibnA:
undetectable		 4qvpH-4ibnA:
21.18
4qvpN-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.19A 4qvqV-4ibnA:
undetectable
4qvqb-4ibnA:
undetectable		 4qvqV-4ibnA:
21.18
4qvqb-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.19A 4qvqH-4ibnA:
undetectable
4qvqN-4ibnA:
undetectable		 4qvqH-4ibnA:
21.18
4qvqN-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.21A 4qvwV-4ibnA:
undetectable
4qvwb-4ibnA:
undetectable		 4qvwV-4ibnA:
21.18
4qvwb-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.21A 4qvwH-4ibnA:
undetectable
4qvwN-4ibnA:
undetectable		 4qvwH-4ibnA:
21.18
4qvwN-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.22A 4qw0V-4ibnA:
undetectable
4qw0b-4ibnA:
undetectable		 4qw0V-4ibnA:
21.18
4qw0b-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.22A 4qw0H-4ibnA:
undetectable
4qw0N-4ibnA:
undetectable		 4qw0H-4ibnA:
21.18
4qw0N-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.21A 4qw1V-4ibnA:
undetectable
4qw1b-4ibnA:
undetectable		 4qw1V-4ibnA:
21.18
4qw1b-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.20A 4qw1H-4ibnA:
undetectable
4qw1N-4ibnA:
undetectable		 4qw1H-4ibnA:
21.18
4qw1N-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.21A 4qw3V-4ibnA:
undetectable
4qw3b-4ibnA:
undetectable		 4qw3V-4ibnA:
21.18
4qw3b-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.21A 4qw3H-4ibnA:
undetectable
4qw3N-4ibnA:
undetectable		 4qw3H-4ibnA:
21.18
4qw3N-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.23A 4qwuV-4ibnA:
undetectable
4qwub-4ibnA:
undetectable		 4qwuV-4ibnA:
21.18
4qwub-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.23A 4qwuH-4ibnA:
undetectable
4qwuN-4ibnA:
undetectable		 4qwuH-4ibnA:
21.18
4qwuN-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		4 / 7 ALA A 162
ARG A  55
GLY A 179
GLU A 181
 None
 0.91A 5btdA-4ibnA:
undetectable
5btdB-4ibnA:
undetectable
5btdC-4ibnA:
undetectable		 5btdA-4ibnA:
18.93
5btdB-4ibnA:
24.23
5btdC-4ibnA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		4 / 7 ALA A 162
ARG A  55
GLY A 179
GLU A 181
 None
 0.95A 5btdA-4ibnA:
undetectable
5btdC-4ibnA:
undetectable
5btdD-4ibnA:
undetectable		 5btdA-4ibnA:
18.93
5btdC-4ibnA:
18.93
5btdD-4ibnA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		4 / 6 ALA A 162
ARG A  55
GLY A 179
GLU A 181
 None
 0.91A 5btgA-4ibnA:
undetectable
5btgB-4ibnA:
undetectable
5btgC-4ibnA:
undetectable		 5btgA-4ibnA:
18.93
5btgB-4ibnA:
24.23
5btgC-4ibnA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.16A 5bxnV-4ibnA:
undetectable
5bxnb-4ibnA:
undetectable		 5bxnV-4ibnA:
20.78
5bxnb-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.15A 5bxnH-4ibnA:
undetectable
5bxnN-4ibnA:
undetectable		 5bxnH-4ibnA:
20.78
5bxnN-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.21A 5cz7H-4ibnA:
undetectable
5cz7N-4ibnA:
undetectable		 5cz7H-4ibnA:
21.18
5cz7N-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.20A 5d0xV-4ibnA:
undetectable
5d0xb-4ibnA:
undetectable		 5d0xV-4ibnA:
21.18
5d0xb-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.20A 5d0xH-4ibnA:
undetectable
5d0xN-4ibnA:
undetectable		 5d0xH-4ibnA:
21.18
5d0xN-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 12 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.19A 5l5zV-4ibnA:
undetectable
5l5zb-4ibnA:
undetectable		 5l5zV-4ibnA:
21.18
5l5zb-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 12 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.18A 5l5zH-4ibnA:
undetectable
5l5zN-4ibnA:
undetectable		 5l5zH-4ibnA:
21.18
5l5zN-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.20A 5l66V-4ibnA:
undetectable
5l66b-4ibnA:
undetectable		 5l66V-4ibnA:
21.18
5l66b-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 11 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.19A 5l66H-4ibnA:
undetectable
5l66N-4ibnA:
undetectable		 5l66H-4ibnA:
21.18
5l66N-4ibnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 12 THR A  95
THR A  94
GLY A  39
ALA A 158
SER A  97
 None
 1.40A 5lf3N-4ibnA:
undetectable		 5lf3N-4ibnA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 12 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.17A 6hwdV-4ibnA:
undetectable
6hwdb-4ibnA:
undetectable		 6hwdV-4ibnA:
20.10
6hwdb-4ibnA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		5 / 12 HIS A 152
THR A  95
THR A  94
GLY A  39
ALA A 158
 None
 1.17A 6hwdH-4ibnA:
undetectable
6hwdN-4ibnA:
undetectable		 6hwdH-4ibnA:
20.10
6hwdN-4ibnA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_A_AM2A301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		4 / 8 ARG A  80
HIS A  84
GLU A  77
GLU A 131
 None
 0.96A 6mn4A-4ibnA:
undetectable		 6mn4A-4ibnA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_D_AM2D301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		4 / 8 ARG A  80
HIS A  84
GLU A  77
GLU A 131
 None
 0.81A 6mn4D-4ibnA:
undetectable		 6mn4D-4ibnA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_F_AM2F301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4ibn RIBONUCLEASE H
(uncultured
organism) 		4 / 7 ARG A  80
HIS A  84
GLU A  77
GLU A 131
 None
 0.94A 6mn4F-4ibnA:
undetectable		 6mn4F-4ibnA:
23.55