SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ibo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1117_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4ibo GLUCONATE
DEHYDROGENASE
(Agrobacterium
fabrum) 		3 / 3 ASP A  44
ARG A  21
ARG A  47
 None
 1.10A 2j9dA-4iboA:
undetectable
2j9dC-4iboA:
undetectable		 2j9dA-4iboA:
20.31
2j9dC-4iboA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 4ibo GLUCONATE
DEHYDROGENASE
(Agrobacterium
fabrum) 		4 / 7 GLY A  30
ALA A 230
VAL A  93
ILE A  38
 None
 0.81A 3a2qA-4iboA:
undetectable		 3a2qA-4iboA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 4ibo GLUCONATE
DEHYDROGENASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 127
ARG A 133
ARG A 128
ILE A  75
GLU A  72
 None
 1.38A 3jb2A-4iboA:
3.8		 3jb2A-4iboA:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 4ibo GLUCONATE
DEHYDROGENASE
(Agrobacterium
fabrum) 		4 / 7 GLY A  35
ALA A  36
ALA A 235
ARG A  12
 None
 0.86A 3ur0B-4iboA:
undetectable		 3ur0B-4iboA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 4ibo GLUCONATE
DEHYDROGENASE
(Agrobacterium
fabrum) 		5 / 12 GLY A  22
GLY A  97
GLY A  24
ASP A 117
ILE A  98
 None
 0.90A 5eifC-4iboA:
undetectable		 5eifC-4iboA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 4ibo GLUCONATE
DEHYDROGENASE
(Agrobacterium
fabrum) 		5 / 12 GLY A  22
GLY A  97
GLY A  24
ASP A 117
ILE A  98
 None
 0.93A 5kqrA-4iboA:
2.0		 5kqrA-4iboA:
25.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 4ibo GLUCONATE
DEHYDROGENASE
(Agrobacterium
fabrum) 		5 / 12 GLY A  22
GLY A  97
GLY A  24
ASP A 117
ILE A  98
 None
 0.92A 5kqsA-4iboA:
2.2		 5kqsA-4iboA:
25.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 4ibo GLUCONATE
DEHYDROGENASE
(Agrobacterium
fabrum) 		5 / 12 GLY A  22
GLY A  97
GLY A  24
ASP A 117
ILE A  98
 None
 0.91A 5m5bA-4iboA:
5.3		 5m5bA-4iboA:
27.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_A_SAMA301_0
(NS5)		 4ibo GLUCONATE
DEHYDROGENASE
(Agrobacterium
fabrum) 		5 / 12 GLY A  22
GLY A  97
GLY A  24
ASP A 117
ILE A  98
 None
 0.88A 5njvA-4iboA:
2.2		 5njvA-4iboA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_B_SAMB301_0
(NS5)		 4ibo GLUCONATE
DEHYDROGENASE
(Agrobacterium
fabrum) 		5 / 12 GLY A  22
GLY A  97
GLY A  24
ASP A 117
ILE A  98
 None
 0.89A 5njvB-4iboA:
2.6		 5njvB-4iboA:
24.84