SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ict'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A4L_C_DCFC1353_2 (ADENOSINE DEAMINASE)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	4 / 5	LEU A 246 LEU A 242 LEU A 145 GLY A 358	None	0.80A	1a4lC-4ictA: undetectable	1a4lC-4ictA: 20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CQE_A_FLPA1650_1 (PROTEIN (PROSTAGLANDIN H2 SYNTHASE-1))	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	5 / 12	VAL A 149 LEU A 150 LEU A 109 GLY A 234 LEU A 350	None None None HEM A 405 (-3.5A) HEM A 405 ( 4.6A)	1.05A	1cqeA-4ictA: 3.7	1cqeA-4ictA: 22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CQE_B_FLPB2650_1 (PROTEIN (PROSTAGLANDIN H2 SYNTHASE-1))	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	5 / 12	VAL A 149 LEU A 150 LEU A 109 GLY A 234 LEU A 350	None None None HEM A 405 (-3.5A) HEM A 405 ( 4.6A)	1.05A	1cqeB-4ictA: undetectable	1cqeB-4ictA: 22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HWI_A_115A2_2 (HMG-COA REDUCTASE)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	4 / 8	HIS A 354 LEU A 242 ALA A 245 LEU A 246	None	0.99A	1hwiB-4ictA: 2.1	1hwiB-4ictA: 22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HWI_D_115D3_1 (HMG-COA REDUCTASE)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	4 / 8	HIS A 354 LEU A 242 ALA A 245 LEU A 246	None	0.98A	1hwiC-4ictA: 1.9	1hwiC-4ictA: 22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A1M_B_CAMB2422_0 (CYTOCHROME P450-CAM)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	4 / 8	PHE A 314 GLY A 15 THR A 244 ILE A 276	None	0.75A	2a1mB-4ictA: 37.3	2a1mB-4ictA: 25.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AYL_B_FLPB2701_1 (PROSTAGLANDIN G/H SYNTHASE 1)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	5 / 12	VAL A 149 LEU A 150 LEU A 109 GLY A 234 LEU A 350	None None None HEM A 405 (-3.5A) HEM A 405 ( 4.6A)	1.05A	2aylB-4ictA: 1.9	2aylB-4ictA: 22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXF_A_DZPA2001_1 (SERUM ALBUMIN)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	5 / 12	LEU A 284 VAL A 307 GLU A 56 LEU A 55 ARG A 340	HEM A 405 (-3.5A) None None None None	1.24A	2bxfA-4ictA: undetectable	2bxfA-4ictA: 21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GLU_B_SAMB302_0 (YCGJ)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	5 / 12	GLY A 358 THR A 238 ARG A 114 ALA A 117 PHE A 137	None HEM A 405 ( 4.5A) None None None	0.89A	2gluB-4ictA: undetectable	2gluB-4ictA: 21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GLU_B_SAMB302_0 (YCGJ)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	5 / 12	GLY A 358 THR A 238 THR A 243 ARG A 114 PHE A 137	None HEM A 405 ( 4.5A) None None None	1.02A	2gluB-4ictA: undetectable	2gluB-4ictA: 21.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2IJ7_A_TPFA2472_1 (CYTOCHROME P450 121)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	11 / 11	THR A 77 VAL A 78 ASN A 85 MET A 86 PHE A 168 THR A 229 ALA A 233 SER A 237 PHE A 280 GLN A 385 ARG A 386	None None 1ED A 406 (-3.7A) HEM A 405 (-4.5A) 1ED A 406 (-4.1A) 1ED A 406 (-4.3A) HEM A 405 ( 3.8A) HEM A 405 (-3.9A) HEM A 405 (-4.2A) 1ED A 406 ( 4.8A) 1ED A 406 ( 4.6A)	0.37A	2ij7A-4ictA: 67.3	2ij7A-4ictA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2IJ7_B_TPFB2470_1 (CYTOCHROME P450 121)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	9 / 9	THR A 77 VAL A 78 ASN A 85 MET A 86 PHE A 168 THR A 229 ALA A 233 GLN A 385 ARG A 386	None None 1ED A 406 (-3.7A) HEM A 405 (-4.5A) 1ED A 406 (-4.1A) 1ED A 406 (-4.3A) HEM A 405 ( 3.8A) 1ED A 406 ( 4.8A) 1ED A 406 ( 4.6A)	0.51A	2ij7B-4ictA: 65.7	2ij7B-4ictA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2IJ7_C_TPFC2471_1 (CYTOCHROME P450 121)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	8 / 8	THR A 77 VAL A 78 VAL A 83 ASN A 85 PHE A 168 ALA A 233 GLN A 385 ARG A 386	None None 1ED A 406 (-3.6A) 1ED A 406 (-3.7A) 1ED A 406 (-4.1A) HEM A 405 ( 3.8A) 1ED A 406 ( 4.8A) 1ED A 406 ( 4.6A)	0.49A	2ij7C-4ictA: 66.5	2ij7C-4ictA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2IJ7_D_TPFD2473_1 (CYTOCHROME P450 121)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	10 / 10	THR A 77 VAL A 78 ASN A 85 PHE A 168 THR A 229 ALA A 233 SER A 237 PHE A 280 GLN A 385 ARG A 386	None None 1ED A 406 (-3.7A) 1ED A 406 (-4.1A) 1ED A 406 (-4.3A) HEM A 405 ( 3.8A) HEM A 405 (-3.9A) HEM A 405 (-4.2A) 1ED A 406 ( 4.8A) 1ED A 406 ( 4.6A)	0.26A	2ij7D-4ictA: 66.4	2ij7D-4ictA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2IJ7_D_TPFD2473_1 (CYTOCHROME P450 121)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	5 / 10	VAL A 83 SER A 237 PHE A 280 GLN A 385 ARG A 386	1ED A 406 (-3.6A) HEM A 405 (-3.9A) HEM A 405 (-4.2A) 1ED A 406 ( 4.8A) 1ED A 406 ( 4.6A)	1.50A	2ij7D-4ictA: 66.4	2ij7D-4ictA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2IJ7_F_TPFF2474_1 (CYTOCHROME P450 121)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	10 / 10	THR A 77 VAL A 78 ASN A 85 MET A 86 PHE A 168 THR A 229 ALA A 233 SER A 237 GLN A 385 ARG A 386	None None 1ED A 406 (-3.7A) HEM A 405 (-4.5A) 1ED A 406 (-4.1A) 1ED A 406 (-4.3A) HEM A 405 ( 3.8A) HEM A 405 (-3.9A) 1ED A 406 ( 4.8A) 1ED A 406 ( 4.6A)	0.31A	2ij7F-4ictA: 66.6	2ij7F-4ictA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2O4S_A_AB1A400_2 (PROTEASE)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	5 / 12	ARG A 184 GLY A 191 ALA A 190 ASP A 220 GLY A 227	None	0.81A	2o4sB-4ictA: undetectable	2o4sB-4ictA: 15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q5K_A_AB1A201_2 (PROTEASE)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	5 / 12	ARG A 184 GLY A 191 ALA A 190 ASP A 220 GLY A 227	None	0.75A	2q5kB-4ictA: undetectable	2q5kB-4ictA: 17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0M_A_KLNA1501_1 (CYTOCHROME P450 3A4)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	5 / 10	ILE A 247 PHE A 314 LEU A 336 ILE A 375 GLY A 323	None	1.23A	2v0mA-4ictA: 26.5	2v0mA-4ictA: 22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V57_A_PRLA1188_0 (TETR FAMILY TRANSCRIPTIONAL REPRESSOR LFRR)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	4 / 8	SER A 248 ILE A 247 ASP A 16 ARG A 14	None	1.09A	2v57A-4ictA: undetectable	2v57A-4ictA: 21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V57_C_PRLC1187_0 (TETR FAMILY TRANSCRIPTIONAL REPRESSOR LFRR)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	4 / 8	SER A 248 ILE A 247 ASP A 16 ARG A 14	None	1.10A	2v57C-4ictA: undetectable	2v57C-4ictA: 21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WA2_B_SAMB1267_0 (NON-STRUCTURAL PROTEIN 5)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	5 / 12	GLY A 191 GLU A 194 VAL A 228 THR A 229 ILE A 186	None None None 1ED A 406 (-4.3A) None	0.99A	2wa2B-4ictA: undetectable	2wa2B-4ictA: 21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IB2_A_IBPA3960_1 (LACTOTRANSFERRIN)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	4 / 4	GLY A 201 VAL A 149 GLY A 227 THR A 229	None None None 1ED A 406 (-4.3A)	0.91A	3ib2A-4ictA: undetectable	3ib2A-4ictA: 24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MWS_B_017B201_1 (HIV-1 PROTEASE)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	5 / 12	ARG A 184 GLY A 191 ALA A 190 ASP A 220 GLY A 227	None	0.80A	3mwsA-4ictA: undetectable	3mwsA-4ictA: 13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N8W_A_FLPA701_1 (PROSTAGLANDIN G/H SYNTHASE 1)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	5 / 12	VAL A 149 LEU A 150 LEU A 109 GLY A 234 LEU A 350	None None None HEM A 405 (-3.5A) HEM A 405 ( 4.6A)	1.02A	3n8wA-4ictA: 1.0	3n8wA-4ictA: 22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NU3_B_478B401_1 (PROTEASE)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	5 / 12	ARG A 184 GLY A 191 ALA A 190 ASP A 220 GLY A 227	None	0.84A	3nu3A-4ictA: undetectable	3nu3A-4ictA: 15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UNI_B_SALB1345_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	4 / 8	GLU A 310 LEU A 308 VAL A 9 ALA A 281	None	0.94A	3uniB-4ictA: undetectable	3uniB-4ictA: 15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RS0_A_IBPA706_1 (PROSTAGLANDIN G/H SYNTHASE 2)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	5 / 9	VAL A 149 LEU A 150 LEU A 109 GLY A 234 LEU A 350	None None None HEM A 405 (-3.5A) HEM A 405 ( 4.6A)	1.01A	4rs0A-4ictA: 1.0	4rs0A-4ictA: 21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WNU_B_QDNB602_1 (CYTOCHROME P450 2D6)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	5 / 9	LEU A 392 PHE A 241 PHE A 137 ALA A 138 ALA A 355	None HEM A 405 ( 4.6A) None None None	1.07A	4wnuB-4ictA: 28.4	4wnuB-4ictA: 23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WQ4_B_ACTB403_0 (TRNA N6-ADENOSINE THREONYLCARBAMOYLTRA NSFERASE)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	3 / 3	ARG A 58 ASP A 57 ARG A 59	SO4 A 401 (-3.8A) None None	0.63A	4wq4B-4ictA: undetectable	4wq4B-4ictA: 23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XT7_A_TOPA302_1 (RV2671)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	5 / 11	ILE A 236 THR A 243 SER A 240 GLY A 239 PHE A 161	None None None None SO4 A 404 (-4.5A)	1.45A	4xt7A-4ictA: undetectable	4xt7A-4ictA: 21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z2E_F_TR6F101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B SYMMETRIZED E-SITE DNA)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	4 / 5	GLY A 339 ARG A 340 GLY A 341 GLU A 56	HEM A 405 (-4.0A) None None None	1.19A	4z2eB-4ictA: undetectable 4z2eC-4ictA: undetectable	4z2eB-4ictA: 24.53 4z2eC-4ictA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E8Q_A_FOLA201_1 (DIHYDROFOLATE REDUCTASE)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	3 / 3	ASP A 20 LEU A 278 ARG A 387	None	0.87A	5e8qA-4ictA: undetectable	5e8qA-4ictA: 17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JWA_A_ACTA612_0 (NADH DEHYDROGENASE, PUTATIVE)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	3 / 3	LYS A 301 ASP A 291 ARG A 59	None	0.93A	5jwaA-4ictA: undetectable 5jwaH-4ictA: undetectable	5jwaA-4ictA: 21.80 5jwaH-4ictA: 21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LJB_A_RTLA201_1 (RETINOL-BINDING PROTEIN 1)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	4 / 8	LEU A 124 LEU A 362 ILE A 388 THR A 243	None	0.95A	5ljbA-4ictA: undetectable	5ljbA-4ictA: 16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5T8H_B_478B401_2 (PROTEASE)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	5 / 12	ARG A 184 GLY A 191 ALA A 190 ASP A 220 GLY A 227	None	0.82A	5t8hB-4ictA: undetectable	5t8hB-4ictA: 15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y9Y_A_ACTA412_0 (UNCHARACTERIZED PROTEIN KDOO)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	3 / 3	ARG A 381 PHE A 161 ARG A 134	SO4 A 404 (-3.6A) SO4 A 404 (-4.5A) SO4 A 404 (-2.7A)	0.93A	5y9yA-4ictA: undetectable	5y9yA-4ictA: 22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DH0_A_017A101_1 (PROTEASE)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	5 / 12	ARG A 184 GLY A 191 ALA A 190 ASP A 220 GLY A 227	None	0.80A	6dh0B-4ictA: undetectable	6dh0B-4ictA: 17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DH3_A_017A101_1 (PROTEASE)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	5 / 12	ARG A 184 GLY A 191 ALA A 190 ASP A 220 GLY A 227	None	0.76A	6dh3B-4ictA: undetectable	6dh3B-4ictA: 17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DH6_A_017A104_1 (PROTEASE)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	5 / 12	ARG A 184 GLY A 191 ALA A 190 ASP A 220 GLY A 227	None	0.77A	6dh6B-4ictA: undetectable	6dh6B-4ictA: 17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DJ1_B_AB1B201_1 (HIV-1 PROTEASE)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	5 / 12	ARG A 184 GLY A 191 ALA A 190 ASP A 220 GLY A 227	None	0.82A	6dj1B-4ictA: undetectable	6dj1B-4ictA: 11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DJ2_B_AB1B201_1 (HIV-1 PROTEASE)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	5 / 12	ARG A 184 GLY A 191 ALA A 190 ASP A 220 GLY A 227	None	0.77A	6dj2B-4ictA: undetectable	6dj2B-4ictA: 10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGD_A_ACTA812_0 (GEPHYRIN)	4ict	CYTOCHROME P450 121 (Mycobacterium tuberculosis)	4 / 6	GLU A 310 ARG A 387 VAL A 9 PRO A 10	None	1.40A	6fgdA-4ictA: undetectable	6fgdA-4ictA: 23.03

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1A4L_C_DCFC1353_2","ADENOSINE DEAMINASE","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",4,"LEU A 246;LEU A 242;LEU A 145;GLY A 358","None","0.80A","1a4lC-4ictA:undetectable","1a4lC-4ictA:20.89"],["1CQE_A_FLPA1650_1","PROTEIN (PROSTAGLANDIN H2 SYNTHASE-1)","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",5,"VAL A 149;LEU A 150;LEU A 109;GLY A 234;LEU A 350","None;None;None;HEM A 405 (-3.5A);HEM A 405 ( 4.6A)","1.05A","1cqeA-4ictA:3.7","1cqeA-4ictA:22.17"],["1CQE_B_FLPB2650_1","PROTEIN (PROSTAGLANDIN H2 SYNTHASE-1)","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",5,"VAL A 149;LEU A 150;LEU A 109;GLY A 234;LEU A 350","None;None;None;HEM A 405 (-3.5A);HEM A 405 ( 4.6A)","1.05A","1cqeB-4ictA:undetectable","1cqeB-4ictA:22.17"],["1HWI_A_115A2_2","HMG-COA REDUCTASE;HMG-COA REDUCTASE","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",4,"HIS A 354;LEU A 242;ALA A 245;LEU A 246","None","0.99A","1hwiB-4ictA:2.1","1hwiB-4ictA:22.80"],["1HWI_D_115D3_1","HMG-COA REDUCTASE;HMG-COA REDUCTASE","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",4,"HIS A 354;LEU A 242;ALA A 245;LEU A 246","None","0.98A","1hwiC-4ictA:1.9","1hwiC-4ictA:22.80"],["2A1M_B_CAMB2422_0","CYTOCHROME P450-CAM","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",4,"PHE A 314;GLY A  15;THR A 244;ILE A 276","None","0.75A","2a1mB-4ictA:37.3","2a1mB-4ictA:25.75"],["2AYL_B_FLPB2701_1","PROSTAGLANDIN G\/H SYNTHASE 1","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",5,"VAL A 149;LEU A 150;LEU A 109;GLY A 234;LEU A 350","None;None;None;HEM A 405 (-3.5A);HEM A 405 ( 4.6A)","1.05A","2aylB-4ictA:1.9","2aylB-4ictA:22.08"],["2BXF_A_DZPA2001_1","SERUM ALBUMIN","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",5,"LEU A 284;VAL A 307;GLU A  56;LEU A  55;ARG A 340","HEM A 405 (-3.5A);None;None;None;None","1.24A","2bxfA-4ictA:undetectable","2bxfA-4ictA:21.84"],["2GLU_B_SAMB302_0","YCGJ","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",5,"GLY A 358;THR A 238;ARG A 114;ALA A 117;PHE A 137","None;HEM A 405 ( 4.5A);None;None;None","0.89A","2gluB-4ictA:undetectable","2gluB-4ictA:21.83"],["2GLU_B_SAMB302_0","YCGJ","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",5,"GLY A 358;THR A 238;THR A 243;ARG A 114;PHE A 137","None;HEM A 405 ( 4.5A);None;None;None","1.02A","2gluB-4ictA:undetectable","2gluB-4ictA:21.83"],["2IJ7_A_TPFA2472_1","CYTOCHROME P450 121","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",11,"THR A  77;VAL A  78;ASN A  85;MET A  86;PHE A 168;THR A 229;ALA A 233;SER A 237;PHE A 280;GLN A 385;ARG A 386","None;None;1ED A 406 (-3.7A);HEM A 405 (-4.5A);1ED A 406 (-4.1A);1ED A 406 (-4.3A);HEM A 405 ( 3.8A);HEM A 405 (-3.9A);HEM A 405 (-4.2A);1ED A 406 ( 4.8A);1ED A 406 ( 4.6A)","0.37A","2ij7A-4ictA:67.3","2ij7A-4ictA:100.00"],["2IJ7_B_TPFB2470_1","CYTOCHROME P450 121","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",9,"THR A  77;VAL A  78;ASN A  85;MET A  86;PHE A 168;THR A 229;ALA A 233;GLN A 385;ARG A 386","None;None;1ED A 406 (-3.7A);HEM A 405 (-4.5A);1ED A 406 (-4.1A);1ED A 406 (-4.3A);HEM A 405 ( 3.8A);1ED A 406 ( 4.8A);1ED A 406 ( 4.6A)","0.51A","2ij7B-4ictA:65.7","2ij7B-4ictA:100.00"],["2IJ7_C_TPFC2471_1","CYTOCHROME P450 121","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",8,"THR A  77;VAL A  78;VAL A  83;ASN A  85;PHE A 168;ALA A 233;GLN A 385;ARG A 386","None;None;1ED A 406 (-3.6A);1ED A 406 (-3.7A);1ED A 406 (-4.1A);HEM A 405 ( 3.8A);1ED A 406 ( 4.8A);1ED A 406 ( 4.6A)","0.49A","2ij7C-4ictA:66.5","2ij7C-4ictA:100.00"],["2IJ7_D_TPFD2473_1","CYTOCHROME P450 121","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",10,"THR A  77;VAL A  78;ASN A  85;PHE A 168;THR A 229;ALA A 233;SER A 237;PHE A 280;GLN A 385;ARG A 386","None;None;1ED A 406 (-3.7A);1ED A 406 (-4.1A);1ED A 406 (-4.3A);HEM A 405 ( 3.8A);HEM A 405 (-3.9A);HEM A 405 (-4.2A);1ED A 406 ( 4.8A);1ED A 406 ( 4.6A)","0.26A","2ij7D-4ictA:66.4","2ij7D-4ictA:100.00"],["2IJ7_D_TPFD2473_1","CYTOCHROME P450 121","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",5,"VAL A  83;SER A 237;PHE A 280;GLN A 385;ARG A 386","1ED A 406 (-3.6A);HEM A 405 (-3.9A);HEM A 405 (-4.2A);1ED A 406 ( 4.8A);1ED A 406 ( 4.6A)","1.50A","2ij7D-4ictA:66.4","2ij7D-4ictA:100.00"],["2IJ7_F_TPFF2474_1","CYTOCHROME P450 121","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",10,"THR A  77;VAL A  78;ASN A  85;MET A  86;PHE A 168;THR A 229;ALA A 233;SER A 237;GLN A 385;ARG A 386","None;None;1ED A 406 (-3.7A);HEM A 405 (-4.5A);1ED A 406 (-4.1A);1ED A 406 (-4.3A);HEM A 405 ( 3.8A);HEM A 405 (-3.9A);1ED A 406 ( 4.8A);1ED A 406 ( 4.6A)","0.31A","2ij7F-4ictA:66.6","2ij7F-4ictA:100.00"],["2O4S_A_AB1A400_2","PROTEASE;PROTEASE","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",5,"ARG A 184;GLY A 191;ALA A 190;ASP A 220;GLY A 227","None","0.81A","2o4sB-4ictA:undetectable","2o4sB-4ictA:15.28"],["2Q5K_A_AB1A201_2","PROTEASE;PROTEASE","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",5,"ARG A 184;GLY A 191;ALA A 190;ASP A 220;GLY A 227","None","0.75A","2q5kB-4ictA:undetectable","2q5kB-4ictA:17.20"],["2V0M_A_KLNA1501_1","CYTOCHROME P450 3A4","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",5,"ILE A 247;PHE A 314;LEU A 336;ILE A 375;GLY A 323","None","1.23A","2v0mA-4ictA:26.5","2v0mA-4ictA:22.97"],["2V57_A_PRLA1188_0","TETR FAMILY TRANSCRIPTIONAL REPRESSOR LFRR","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",4,"SER A 248;ILE A 247;ASP A  16;ARG A  14","None","1.09A","2v57A-4ictA:undetectable","2v57A-4ictA:21.52"],["2V57_C_PRLC1187_0","TETR FAMILY TRANSCRIPTIONAL REPRESSOR LFRR","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",4,"SER A 248;ILE A 247;ASP A  16;ARG A  14","None","1.10A","2v57C-4ictA:undetectable","2v57C-4ictA:21.52"],["2WA2_B_SAMB1267_0","NON-STRUCTURAL PROTEIN 5","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",5,"GLY A 191;GLU A 194;VAL A 228;THR A 229;ILE A 186","None;None;None;1ED A 406 (-4.3A);None","0.99A","2wa2B-4ictA:undetectable","2wa2B-4ictA:21.04"],["3IB2_A_IBPA3960_1","LACTOTRANSFERRIN","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",4,"GLY A 201;VAL A 149;GLY A 227;THR A 229","None;None;None;1ED A 406 (-4.3A)","0.91A","3ib2A-4ictA:undetectable","3ib2A-4ictA:24.51"],["3MWS_B_017B201_1","HIV-1 PROTEASE;HIV-1 PROTEASE","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",5,"ARG A 184;GLY A 191;ALA A 190;ASP A 220;GLY A 227","None","0.80A","3mwsA-4ictA:undetectable","3mwsA-4ictA:13.95"],["3N8W_A_FLPA701_1","PROSTAGLANDIN G\/H SYNTHASE 1","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",5,"VAL A 149;LEU A 150;LEU A 109;GLY A 234;LEU A 350","None;None;None;HEM A 405 (-3.5A);HEM A 405 ( 4.6A)","1.02A","3n8wA-4ictA:1.0","3n8wA-4ictA:22.08"],["3NU3_B_478B401_1","PROTEASE;PROTEASE","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",5,"ARG A 184;GLY A 191;ALA A 190;ASP A 220;GLY A 227","None","0.84A","3nu3A-4ictA:undetectable","3nu3A-4ictA:15.16"],["3UNI_B_SALB1345_1","XANTHINE DEHYDROGENASE\/OXIDASE","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",4,"GLU A 310;LEU A 308;VAL A   9;ALA A 281","None","0.94A","3uniB-4ictA:undetectable","3uniB-4ictA:15.88"],["4RS0_A_IBPA706_1","PROSTAGLANDIN G\/H SYNTHASE 2","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",5,"VAL A 149;LEU A 150;LEU A 109;GLY A 234;LEU A 350","None;None;None;HEM A 405 (-3.5A);HEM A 405 ( 4.6A)","1.01A","4rs0A-4ictA:1.0","4rs0A-4ictA:21.37"],["4WNU_B_QDNB602_1","CYTOCHROME P450 2D6","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",5,"LEU A 392;PHE A 241;PHE A 137;ALA A 138;ALA A 355","None;HEM A 405 ( 4.6A);None;None;None","1.07A","4wnuB-4ictA:28.4","4wnuB-4ictA:23.62"],["4WQ4_B_ACTB403_0","TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",3,"ARG A  58;ASP A  57;ARG A  59","SO4 A 401 (-3.8A);None;None","0.63A","4wq4B-4ictA:undetectable","4wq4B-4ictA:23.08"],["4XT7_A_TOPA302_1","RV2671","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",5,"ILE A 236;THR A 243;SER A 240;GLY A 239;PHE A 161","None;None;None;None;SO4 A 404 (-4.5A)","1.45A","4xt7A-4ictA:undetectable","4xt7A-4ictA:21.87"],["4Z2E_F_TR6F101_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;SYMMETRIZED E-SITE DNA","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",4,"GLY A 339;ARG A 340;GLY A 341;GLU A  56","HEM A 405 (-4.0A);None;None;None","1.19A","4z2eB-4ictA:undetectable;4z2eC-4ictA:undetectable","4z2eB-4ictA:24.53;4z2eC-4ictA:18.53"],["5E8Q_A_FOLA201_1","DIHYDROFOLATE REDUCTASE","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",3,"ASP A  20;LEU A 278;ARG A 387","None","0.87A","5e8qA-4ictA:undetectable","5e8qA-4ictA:17.83"],["5JWA_A_ACTA612_0","NADH DEHYDROGENASE, PUTATIVE","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",3,"LYS A 301;ASP A 291;ARG A  59","None","0.93A","5jwaA-4ictA:undetectable;5jwaH-4ictA:undetectable","5jwaA-4ictA:21.80;5jwaH-4ictA:21.80"],["5LJB_A_RTLA201_1","RETINOL-BINDING PROTEIN 1","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",4,"LEU A 124;LEU A 362;ILE A 388;THR A 243","None","0.95A","5ljbA-4ictA:undetectable","5ljbA-4ictA:16.75"],["5T8H_B_478B401_2","PROTEASE","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",5,"ARG A 184;GLY A 191;ALA A 190;ASP A 220;GLY A 227","None","0.82A","5t8hB-4ictA:undetectable","5t8hB-4ictA:15.16"],["5Y9Y_A_ACTA412_0","UNCHARACTERIZED PROTEIN KDOO","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",3,"ARG A 381;PHE A 161;ARG A 134","SO4 A 404 (-3.6A);SO4 A 404 (-4.5A);SO4 A 404 (-2.7A)","0.93A","5y9yA-4ictA:undetectable","5y9yA-4ictA:22.83"],["6DH0_A_017A101_1","PROTEASE","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",5,"ARG A 184;GLY A 191;ALA A 190;ASP A 220;GLY A 227","None","0.80A","6dh0B-4ictA:undetectable","6dh0B-4ictA:17.75"],["6DH3_A_017A101_1","PROTEASE","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",5,"ARG A 184;GLY A 191;ALA A 190;ASP A 220;GLY A 227","None","0.76A","6dh3B-4ictA:undetectable","6dh3B-4ictA:17.75"],["6DH6_A_017A104_1","PROTEASE","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",5,"ARG A 184;GLY A 191;ALA A 190;ASP A 220;GLY A 227","None","0.77A","6dh6B-4ictA:undetectable","6dh6B-4ictA:17.75"],["6DJ1_B_AB1B201_1","HIV-1 PROTEASE","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",5,"ARG A 184;GLY A 191;ALA A 190;ASP A 220;GLY A 227","None","0.82A","6dj1B-4ictA:undetectable","6dj1B-4ictA:11.23"],["6DJ2_B_AB1B201_1","HIV-1 PROTEASE","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",5,"ARG A 184;GLY A 191;ALA A 190;ASP A 220;GLY A 227","None","0.77A","6dj2B-4ictA:undetectable","6dj2B-4ictA:10.96"],["6FGD_A_ACTA812_0","GEPHYRIN","4ict","CYTOCHROME P450 121","Mycobacterium tuberculosis",4,"GLU A 310;ARG A 387;VAL A   9;PRO A  10","None","1.40A","6fgdA-4ictA:undetectable","6fgdA-4ictA:23.03"]]