SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4id0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13GS_A_SASA211_1
(GLUTATHIONE
S-TRANSFERASE)		 4id0 GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF
(Pseudomonas
fluorescens) 		5 / 10 PRO A  10
ILE A 191
TYR A 188
PRO A 202
GLY A 166
 None
 0.91A 13gsA-4id0A:
15.8		 13gsA-4id0A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13GS_B_SASB211_1
(GLUTATHIONE
S-TRANSFERASE)		 4id0 GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF
(Pseudomonas
fluorescens) 		5 / 9 PRO A  10
ILE A 191
TYR A 188
PRO A 202
GLY A 166
 None
 0.91A 13gsB-4id0A:
15.9		 13gsB-4id0A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 4id0 GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF
(Pseudomonas
fluorescens) 		4 / 7 VAL A  28
TYR A  73
LEU A  18
LEU A  19
 None
 0.85A 1cqpA-4id0A:
undetectable
1cqpB-4id0A:
undetectable		 1cqpA-4id0A:
18.72
1cqpB-4id0A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4id0 GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF
(Pseudomonas
fluorescens) 		4 / 4 ALA A 157
VAL A 161
ALA A 158
HIS A 153
 None
None
None
GOL  A 304 (-4.3A)
 1.26A 1q23F-4id0A:
undetectable		 1q23F-4id0A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 4id0 GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF
(Pseudomonas
fluorescens) 		3 / 3 ASP A  47
PHE A   4
ARG A  57
 None
 0.79A 2a3aA-4id0A:
undetectable		 2a3aA-4id0A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_B_VIAB902_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4id0 GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF
(Pseudomonas
fluorescens) 		5 / 12 ALA A 146
ILE A 147
VAL A 161
ALA A 162
ILE A 191
 None
 0.80A 2h42B-4id0A:
undetectable		 2h42B-4id0A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4id0 GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF
(Pseudomonas
fluorescens) 		5 / 12 ALA A 146
ILE A 147
VAL A 161
ALA A 162
ILE A 191
 None
 0.77A 2h42C-4id0A:
undetectable		 2h42C-4id0A:
19.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TOU_A_ACTA228_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 4id0 GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF
(Pseudomonas
fluorescens) 		4 / 4 ALA A   8
ARG A 112
TYR A 167
ARG A 171
 ACT  A 303 ( 3.9A)
None
ACT  A 303 (-4.5A)
ACT  A 303 (-4.0A)
 0.81A 3touA-4id0A:
27.7		 3touA-4id0A:
42.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TOU_B_ACTB228_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 4id0 GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF
(Pseudomonas
fluorescens) 		4 / 4 ALA A   8
ARG A 112
TYR A 167
ARG A 171
 ACT  A 303 ( 3.9A)
None
ACT  A 303 (-4.5A)
ACT  A 303 (-4.0A)
 0.50A 3touB-4id0A:
28.1		 3touB-4id0A:
42.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IJI_F_BEZF501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 4id0 GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF
(Pseudomonas
fluorescens) 		8 / 8 ASN A   6
ALA A   8
SER A   9
LEU A  35
ARG A 112
TYR A 113
TYR A 167
ARG A 171
 None
ACT  A 303 ( 3.9A)
ACT  A 302 ( 4.2A)
ACT  A 302 (-3.9A)
None
ACT  A 302 ( 4.5A)
ACT  A 303 (-4.5A)
ACT  A 303 (-4.0A)
 0.66A 4ijiF-4id0A:
34.2		 4ijiF-4id0A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 4id0 GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF
(Pseudomonas
fluorescens) 		7 / 7 ASN A   6
ALA A   8
SER A   9
VAL A 109
ARG A 112
TYR A 167
ARG A 171
 None
ACT  A 303 ( 3.9A)
ACT  A 302 ( 4.2A)
None
None
ACT  A 303 (-4.5A)
ACT  A 303 (-4.0A)
 0.30A 4ijiH-4id0A:
32.5		 4ijiH-4id0A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4id0 GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF
(Pseudomonas
fluorescens) 		4 / 6 TYR A  11
LEU A 168
VAL A 141
ALA A 140
 ACT  A 301 (-3.8A)
None
None
None
 0.85A 4nkvC-4id0A:
undetectable		 4nkvC-4id0A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1007_1
(SERUM ALBUMIN)		 4id0 GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF
(Pseudomonas
fluorescens) 		5 / 9 LEU A 184
LEU A 100
ILE A 104
SER A 160
ALA A 162
 None
 1.06A 4z69A-4id0A:
2.1		 4z69A-4id0A:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4id0 GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF
(Pseudomonas
fluorescens) 		4 / 6 ARG A  91
ASP A  72
ARG A  68
ILE A 156
 None
 1.33A 5a06A-4id0A:
undetectable		 5a06A-4id0A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 4id0 GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF
(Pseudomonas
fluorescens) 		4 / 6 LYS A  14
SER A 108
VAL A 109
ASP A 102
 ACT  A 301 ( 4.7A)
None
None
None
 1.24A 5hesA-4id0A:
undetectable		 5hesA-4id0A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_D_DAHD60_1
(PUTATIVE CYTOCHROME
C)		 4id0 GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF
(Pseudomonas
fluorescens) 		4 / 5 HIS A  20
ASN A  26
VAL A  28
LEU A  30
 None
 1.35A 5xdhD-4id0A:
undetectable		 5xdhD-4id0A:
11.43