SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4id3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_0
(CYTOCHROME P450 2R1)		 4id3 DNA REPAIR PROTEIN
REV1
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 226
ALA A 210
VAL A 205
GLU A 220
THR A 250
 None
 1.21A 3dl9A-4id3A:
undetectable		 3dl9A-4id3A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_B_MTXB164_2
(DIHYDROFOLATE
REDUCTASE)		 4id3 DNA REPAIR PROTEIN
REV1
(Saccharomyces
cerevisiae) 		4 / 4 PHE A 166
LYS A 164
ILE A 232
THR A 206
 None
 1.49A 3ia4B-4id3A:
undetectable		 3ia4B-4id3A:
20.25