SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4idi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_C_SALC1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4idi ORYZA SATIVA
RURM1-RELATED
(Plasmodium
yoelii) 		4 / 7 ILE A 116
PHE A   9
PHE A  54
ILE A  43
 None
 0.81A 2y7wC-4idiA:
undetectable		 2y7wC-4idiA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 4idi ORYZA SATIVA
RURM1-RELATED
(Plasmodium
yoelii) 		3 / 3 SER A  55
GLU A  37
ASP A  58
 None
 0.87A 3bwmA-4idiA:
undetectable		 3bwmA-4idiA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1X_A_ADNA1450_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 4idi ORYZA SATIVA
RURM1-RELATED
(Plasmodium
yoelii) 		5 / 10 ILE A  48
ILE A  43
ILE A  91
SER A 120
SER A  15
 None
 1.12A 3o1xA-4idiA:
undetectable		 3o1xA-4idiA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGT_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4idi ORYZA SATIVA
RURM1-RELATED
(Plasmodium
yoelii) 		5 / 10 ILE A  47
PHE A   9
SER A  55
ILE A  91
ILE A  43
 None
 1.24A 3qgtA-4idiA:
undetectable		 3qgtA-4idiA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 4idi ORYZA SATIVA
RURM1-RELATED
(Plasmodium
yoelii) 		5 / 10 ILE A  48
ILE A  43
ILE A  91
SER A 120
SER A  15
 None
 1.05A 3qgzA-4idiA:
undetectable		 3qgzA-4idiA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4idi ORYZA SATIVA
RURM1-RELATED
(Plasmodium
yoelii) 		4 / 8 SER A  55
ARG A  44
GLU A  37
ILE A  40
 None
 1.02A 4d33A-4idiA:
undetectable		 4d33A-4idiA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4idi ORYZA SATIVA
RURM1-RELATED
(Plasmodium
yoelii) 		4 / 7 SER A  55
ARG A  44
GLU A  37
ILE A  40
 None
 1.07A 4d33B-4idiA:
undetectable		 4d33B-4idiA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4idi ORYZA SATIVA
RURM1-RELATED
(Plasmodium
yoelii) 		4 / 8 SER A  55
ARG A  44
GLU A  37
ILE A  40
 None
 1.12A 4d39A-4idiA:
undetectable		 4d39A-4idiA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4idi ORYZA SATIVA
RURM1-RELATED
(Plasmodium
yoelii) 		4 / 7 SER A  55
ARG A  44
GLU A  37
ILE A  40
 None
 1.08A 4d39B-4idiA:
undetectable		 4d39B-4idiA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M51_A_BEZA501_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 4idi ORYZA SATIVA
RURM1-RELATED
(Plasmodium
yoelii) 		4 / 6 ILE A  40
ILE A 110
PHE A 118
LEU A   7
 None
 0.96A 4m51A-4idiA:
undetectable		 4m51A-4idiA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_0
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 4idi ORYZA SATIVA
RURM1-RELATED
(Plasmodium
yoelii) 		5 / 12 VAL A  71
VAL A  25
ASP A  83
PHE A  42
ILE A  40
 None
 1.44A 6mxtA-4idiA:
undetectable		 6mxtA-4idiA:
16.06