SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4idj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 4idj FAB HEAVY CHAIN
FAB LIGHT CHAIN
(Homo
sapiens) 		7 / 12 TYR L  36
GLN L  89
PHE L  98
ASN H  35
VAL H  37
ALA H  93
TRP H 103
 None
 0.84A 1h8sA-4idjL:
21.6		 1h8sA-4idjL:
40.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1867_0
(FPRA)		 4idj FAB HEAVY CHAIN
(Homo
sapiens) 		4 / 4 ALA H  40
ARG H  38
GLN H  43
GLU H  46
 None
 1.04A 1lqtB-4idjH:
undetectable		 1lqtB-4idjH:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1424_0
(FPRA)		 4idj FAB HEAVY CHAIN
(Homo
sapiens) 		4 / 4 ALA H  40
ARG H  38
GLN H  43
GLU H  46
 None
 1.08A 1lquB-4idjH:
undetectable		 1lquB-4idjH:
18.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RUA_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 4idj FAB HEAVY CHAIN
FAB LIGHT CHAIN
(Homo
sapiens;
Homo
sapiens) 		5 / 10 ALA H  33
ASN H  35
TRP H  47
PHE L  32
TYR L  96
 None
 0.75A 1ruaH-4idjH:
19.2
1ruaL-4idjH:
15.3		 1ruaH-4idjH:
50.65
1ruaL-4idjH:
26.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 4idj FAB HEAVY CHAIN
FAB LIGHT CHAIN
(Homo
sapiens;
Homo
sapiens) 		4 / 8 MET L 175
LEU L 136
SER H 179
VAL L 159
 None
 1.11A 2qd2A-4idjL:
undetectable		 2qd2A-4idjL:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 4idj FAB HEAVY CHAIN
(Homo
sapiens) 		4 / 5 VAL H 121
VAL H 150
ASP H 199
SER H 153
 None
 1.01A 2x45A-4idjH:
undetectable		 2x45A-4idjH:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)		 4idj FAB HEAVY CHAIN
(Homo
sapiens) 		4 / 5 VAL H 121
VAL H 150
ASP H 199
SER H 153
 None
 1.07A 2x45C-4idjH:
undetectable		 2x45C-4idjH:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 4idj FAB HEAVY CHAIN
(Homo
sapiens) 		4 / 4 VAL H  32
VAL H  37
ASN H  35
TRP H  47
 None
 1.40A 2y01B-4idjH:
undetectable		 2y01B-4idjH:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_3
(PHOSPHOLIPASE A2)		 4idj FAB HEAVY CHAIN
FAB LIGHT CHAIN
(Homo
sapiens) 		4 / 5 VAL H 181
VAL H 182
THR L 114
THR H 165
 None
 1.24A 3bjwG-4idjH:
undetectable		 3bjwG-4idjH:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 4idj FAB HEAVY CHAIN
FAB LIGHT CHAIN
(Homo
sapiens;
Homo
sapiens) 		5 / 12 ILE L  48
GLN L   6
TYR L  86
GLN H  39
LEU H  45
 None
 1.42A 4qztA-4idjL:
undetectable		 4qztA-4idjL:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 4idj FAB HEAVY CHAIN
FAB LIGHT CHAIN
(Homo
sapiens;
Homo
sapiens) 		5 / 12 PRO L 113
MET L 175
VAL L 115
ILE L 117
LEU H 124
 None
 1.29A 5tiwB-4idjL:
undetectable		 5tiwB-4idjL:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 4idj FAB LIGHT CHAIN
(Homo
sapiens) 		3 / 3 ARG L  45
PRO L  59
TYR L  86
 None
 1.06A 5tzoB-4idjL:
undetectable		 5tzoB-4idjL:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 4idj FAB HEAVY CHAIN
FAB LIGHT CHAIN
(Homo
sapiens) 		5 / 12 PHE L  98
LEU L   4
GLN L  90
PRO H 100
THR H 100
 None
 1.24A 5xxiA-4idjL:
undetectable		 5xxiA-4idjL:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_2
(GLUCOAMYLASE P)		 4idj FAB HEAVY CHAIN
FAB LIGHT CHAIN
(Homo
sapiens) 		3 / 3 TRP H  47
GLU H  46
GLU L   1
 None
 1.01A 6fhwA-4idjH:
3.9		 6fhwA-4idjH:
17.22