SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4if5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 4if5 ALPHA-TUBULIN
N-ACETYLTRANSFERASE
(Homo
sapiens) 		4 / 8 TYR A 101
GLU A 117
VAL A  76
HIS A  75
 None
None
None
CL  A 202 (-4.4A)
 1.26A 3b9lA-4if5A:
undetectable		 3b9lA-4if5A:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 4if5 ALPHA-TUBULIN
N-ACETYLTRANSFERASE
(Homo
sapiens) 		5 / 12 LEU A 164
VAL A 184
PRO A 159
THR A  65
SER A  54
 None
None
None
CL  A 202 (-4.0A)
None
 1.26A 4hvcB-4if5A:
undetectable		 4hvcB-4if5A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J7W_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 4if5 ALPHA-TUBULIN
N-ACETYLTRANSFERASE
(Homo
sapiens) 		5 / 12 ILE A  97
LEU A  18
LEU A  80
GLY A  95
ILE A  15
 None
 1.03A 5j7wD-4if5A:
undetectable		 5j7wD-4if5A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_A_HFGA1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4if5 ALPHA-TUBULIN
N-ACETYLTRANSFERASE
(Homo
sapiens) 		5 / 12 LEU A 164
VAL A 184
PRO A 159
THR A  65
SER A  54
 None
None
None
CL  A 202 (-4.0A)
None
 1.25A 5xiqA-4if5A:
undetectable		 5xiqA-4if5A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4if5 ALPHA-TUBULIN
N-ACETYLTRANSFERASE
(Homo
sapiens) 		5 / 12 LEU A 164
VAL A 184
PRO A 159
THR A  65
SER A  54
 None
None
None
CL  A 202 (-4.0A)
None
 1.30A 5xiqB-4if5A:
undetectable		 5xiqB-4if5A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN8_A_HFGA603_0
(UNCHARACTERIZED
PROTEIN)		 4if5 ALPHA-TUBULIN
N-ACETYLTRANSFERASE
(Homo
sapiens) 		5 / 12 LEU A 164
VAL A 184
PRO A 159
THR A  65
SER A  54
 None
None
None
CL  A 202 (-4.0A)
None
 1.26A 6mn8A-4if5A:
undetectable		 6mn8A-4if5A:
15.84