SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ig7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4ig7 UBIQUITIN C-TERMINAL
HYDROLASE 37
(Trichinella
spiralis) 		5 / 12 ILE A 222
ALA A 220
LEU A 218
LEU A  90
ALA A  89
 None
 1.26A 1g5yB-4ig7A:
undetectable		 1g5yB-4ig7A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H1D_A_SAMA301_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 4ig7 UBIQUITIN C-TERMINAL
HYDROLASE 37
(Trichinella
spiralis) 		5 / 12 VAL A 168
GLY A  48
TYR A 173
GLN A 225
HIS A  47
 None
 1.19A 1h1dA-4ig7A:
undetectable		 1h1dA-4ig7A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VID_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 4ig7 UBIQUITIN C-TERMINAL
HYDROLASE 37
(Trichinella
spiralis) 		5 / 12 VAL A 168
GLY A  48
TYR A 173
GLN A 225
HIS A  47
 None
 1.20A 1vidA-4ig7A:
undetectable		 1vidA-4ig7A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 4ig7 UBIQUITIN C-TERMINAL
HYDROLASE 37
(Trichinella
spiralis) 		5 / 12 THR A 128
LEU A 127
ILE A 133
VAL A 136
LEU A  95
 None
 1.25A 1wsvB-4ig7A:
undetectable		 1wsvB-4ig7A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_O_C41O1327_2
(RENIN)		 4ig7 UBIQUITIN C-TERMINAL
HYDROLASE 37
(Trichinella
spiralis) 		4 / 8 TYR A 262
SER A 139
SER A  87
LEU A  28
 None
 1.08A 2v0zO-4ig7A:
undetectable		 2v0zO-4ig7A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 4ig7 UBIQUITIN C-TERMINAL
HYDROLASE 37
(Trichinella
spiralis) 		4 / 5 VAL A 166
TYR A 173
VAL A  74
ASP A  73
 None
 1.28A 2x45A-4ig7A:
undetectable		 2x45A-4ig7A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)		 4ig7 UBIQUITIN C-TERMINAL
HYDROLASE 37
(Trichinella
spiralis) 		4 / 5 VAL A 166
TYR A 173
VAL A  74
ASP A  73
 None
 1.23A 2x45C-4ig7A:
undetectable		 2x45C-4ig7A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 4ig7 UBIQUITIN C-TERMINAL
HYDROLASE 37
(Trichinella
spiralis) 		5 / 12 VAL A 168
GLY A  48
TYR A 173
GLN A 225
HIS A  47
 None
 1.25A 3bwmA-4ig7A:
undetectable		 3bwmA-4ig7A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_0
(COMT PROTEIN)		 4ig7 UBIQUITIN C-TERMINAL
HYDROLASE 37
(Trichinella
spiralis) 		5 / 12 VAL A 168
GLY A  48
TYR A 173
GLN A 225
HIS A  47
 None
 1.25A 3bwyA-4ig7A:
undetectable		 3bwyA-4ig7A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_F_BEZF501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 4ig7 UBIQUITIN C-TERMINAL
HYDROLASE 37
(Trichinella
spiralis) 		4 / 8 ALA A  84
SER A  87
LEU A 127
ARG A 134
 None
 1.22A 4ijiF-4ig7A:
undetectable		 4ijiF-4ig7A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JI8_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 4ig7 UBIQUITIN C-TERMINAL
HYDROLASE 37
(Trichinella
spiralis) 		3 / 3 LYS A  57
LYS A 157
TRP A  55
 None
 1.10A 4ji8L-4ig7A:
0.0		 4ji8L-4ig7A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA206_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 4ig7 UBIQUITIN C-TERMINAL
HYDROLASE 37
(Trichinella
spiralis) 		4 / 4 ALA A 250
ALA A 253
ALA A 254
ALA A 257
 None
 0.08A 4oadA-4ig7A:
undetectable		 4oadA-4ig7A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA208_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 4ig7 UBIQUITIN C-TERMINAL
HYDROLASE 37
(Trichinella
spiralis) 		4 / 4 ALA A 250
ALA A 253
ALA A 254
ALA A 257
 None
 0.10A 4oaeA-4ig7A:
undetectable		 4oaeA-4ig7A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_B_STRB601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 4ig7 UBIQUITIN C-TERMINAL
HYDROLASE 37
(Trichinella
spiralis) 		5 / 9 ALA A 198
ILE A 222
VAL A  30
GLY A  48
ILE A 202
 None
 1.05A 4r21B-4ig7A:
undetectable		 4r21B-4ig7A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 4ig7 UBIQUITIN C-TERMINAL
HYDROLASE 37
(Trichinella
spiralis) 		5 / 12 VAL A 168
GLY A  48
TYR A 173
GLN A 225
HIS A  47
 None
 1.24A 4xucA-4ig7A:
undetectable		 4xucA-4ig7A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 4ig7 UBIQUITIN C-TERMINAL
HYDROLASE 37
(Trichinella
spiralis) 		5 / 12 VAL A 168
GLY A  48
TYR A 173
GLN A 225
HIS A  47
 None
 1.27A 4xudA-4ig7A:
undetectable		 4xudA-4ig7A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_B_SAMB303_0
(CATECHOL
O-METHYLTRANSFERASE)		 4ig7 UBIQUITIN C-TERMINAL
HYDROLASE 37
(Trichinella
spiralis) 		5 / 12 VAL A 168
GLY A  48
TYR A 173
GLN A 225
HIS A  47
 None
 1.25A 4xueB-4ig7A:
undetectable		 4xueB-4ig7A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_A_C2FA402_0
(THYMIDYLATE SYNTHASE)		 4ig7 UBIQUITIN C-TERMINAL
HYDROLASE 37
(Trichinella
spiralis) 		5 / 11 ILE A  81
LEU A 178
LEU A 127
GLY A 124
ALA A  89
 None
 1.34A 5fctA-4ig7A:
undetectable		 5fctA-4ig7A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 4ig7 UBIQUITIN C-TERMINAL
HYDROLASE 37
(Trichinella
spiralis) 		5 / 12 VAL A 168
GLY A  48
TYR A 173
GLN A 225
HIS A  47
 None
 1.16A 5fhrA-4ig7A:
undetectable		 5fhrA-4ig7A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_2
(ESTROGEN RECEPTOR)		 4ig7 UBIQUITIN C-TERMINAL
HYDROLASE 37
(Trichinella
spiralis) 		4 / 6 LEU A  90
LEU A  93
LEU A 108
HIS A  21
 None
 0.97A 5gs4A-4ig7A:
undetectable		 5gs4A-4ig7A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 4ig7 UBIQUITIN C-TERMINAL
HYDROLASE 37
(Trichinella
spiralis) 		4 / 6 LEU A   8
ILE A  50
MET A 219
MET A  19
 None
 1.44A 5ljeA-4ig7A:
undetectable		 5ljeA-4ig7A:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_D_ACTD404_0
(L-LYSINE
3-HYDROXYLASE)		 4ig7 UBIQUITIN C-TERMINAL
HYDROLASE 37
(Trichinella
spiralis) 		4 / 6 GLN A  79
TRP A   6
HIS A 137
GLN A  88
 None
 1.39A 6f6jC-4ig7A:
undetectable
6f6jD-4ig7A:
undetectable		 6f6jC-4ig7A:
22.73
6f6jD-4ig7A:
22.73