SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4igo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 4igo OS05G0196500 PROTEIN
(Oryza
sativa) 		4 / 6 LEU A 219
TRP A 414
TYR A 415
VAL A 319
 None
 1.00A 1db1A-4igoA:
undetectable		 1db1A-4igoA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4igo OS05G0196500 PROTEIN
(Oryza
sativa) 		4 / 8 ALA A 480
TRP A 393
GLY A 182
ILE A 183
 None
 0.67A 2zm9A-4igoA:
undetectable		 2zm9A-4igoA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX94_0
(PROTEIN S100-B)		 4igo OS05G0196500 PROTEIN
(Oryza
sativa) 		3 / 3 PHE A 157
CYH A 184
PHE A 477
 None
 0.97A 3cr5X-4igoA:
undetectable		 3cr5X-4igoA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KDM_B_TESB226_1
(IMMUNOGLOBULIN LIGHT
CHAIN
IMMUNOGLOBULIN HEAVY
CHAIN)		 4igo OS05G0196500 PROTEIN
(Oryza
sativa) 		5 / 9 PRO A 453
TRP A 393
ALA A 483
TYR A 415
TYR A 306
 None
 1.40A 3kdmA-4igoA:
0.0
3kdmB-4igoA:
0.0		 3kdmA-4igoA:
21.10
3kdmB-4igoA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_L_CLML221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4igo OS05G0196500 PROTEIN
(Oryza
sativa) 		5 / 12 PHE A 473
PHE A 164
SER A 352
LEU A 359
VAL A 495
 None
 1.45A 3u9fJ-4igoA:
undetectable
3u9fL-4igoA:
undetectable		 3u9fJ-4igoA:
19.46
3u9fL-4igoA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4igo OS05G0196500 PROTEIN
(Oryza
sativa) 		5 / 11 PHE A 164
SER A 352
LEU A 359
VAL A 495
PHE A 473
 None
 1.48A 3u9fN-4igoA:
undetectable
3u9fO-4igoA:
undetectable		 3u9fN-4igoA:
19.46
3u9fO-4igoA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 4igo OS05G0196500 PROTEIN
(Oryza
sativa) 		4 / 5 PHE A 287
TYR A 286
PHE A 282
ILE A 302
 None
 1.12A 4jx1E-4igoA:
undetectable		 4jx1E-4igoA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H4D_A_BBIA403_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 4igo OS05G0196500 PROTEIN
(Oryza
sativa) 		4 / 6 ARG A 148
PHE A 485
GLU A 153
VAL A 467
 None
 1.17A 5h4dA-4igoA:
undetectable		 5h4dA-4igoA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA605_0
(ALPHA-AMYLASE)		 4igo OS05G0196500 PROTEIN
(Oryza
sativa) 		4 / 8 TYR A 481
GLY A 182
ILE A 183
PRO A 453
 None
 0.87A 6ag0A-4igoA:
undetectable		 6ag0A-4igoA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I0Y_A_TRPA3001_0
(23S RIBOSOMAL RNA
TRYPTOPHANASE OPERON
LEADER PEPTIDE)		 4igo OS05G0196500 PROTEIN
(Oryza
sativa) 		3 / 3 TRP A 141
ILE A 302
ASP A 301
 None
 0.87A 6i0y7-4igoA:
undetectable		 6i0y7-4igoA:
4.39