SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4igu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 4igu CG5036
(Drosophila
melanogaster) 		3 / 3 ASN A 101
GLU A  98
ARG A  97
 CL  A 203 (-3.6A)
None
CL  A 203 (-4.7A)
 0.88A 3wxoA-4iguA:
undetectable		 3wxoA-4iguA:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 4igu CG5036
(Drosophila
melanogaster) 		4 / 7 LYS A  73
LEU A  69
GLU A  64
SER A  66
 None
 0.96A 4tvtA-4iguA:
undetectable		 4tvtA-4iguA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4igu CG5036
(Drosophila
melanogaster) 		4 / 8 ILE A 119
LEU A 122
ARG A  36
LEU A  43
 None
 0.94A 5zcoA-4iguA:
undetectable
5zcoJ-4iguA:
undetectable		 5zcoA-4iguA:
13.31
5zcoJ-4iguA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4igu CG5036
(Drosophila
melanogaster) 		4 / 7 ILE A 119
LEU A 122
ARG A  36
LEU A  43
 None
 0.87A 5zcqA-4iguA:
undetectable
5zcqJ-4iguA:
undetectable		 5zcqA-4iguA:
13.31
5zcqJ-4iguA:
15.44