SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4igv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1AV2_D_DVAD8_0 (GRAMICIDIN A)	4igv	KIROLA (Actinidia deliciosa)	3 / 3	VAL A 103 VAL A 105 TRP A 116	None	0.82A	1av2C-4igvA: undetectable 1av2D-4igvA: undetectable	1av2C-4igvA: 8.08 1av2D-4igvA: 8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1W5U_D_DVAD8_0 (GRAMICIDIN D)	4igv	KIROLA (Actinidia deliciosa)	3 / 3	VAL A 103 VAL A 105 TRP A 116	None	0.83A	1w5uC-4igvA: undetectable 1w5uD-4igvA: undetectable	1w5uC-4igvA: 8.08 1w5uD-4igvA: 8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z11_B_8MOB501_0 (CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 6)	4igv	KIROLA (Actinidia deliciosa)	5 / 11	PHE A 136 ASN A 38 ILE A 39 ILE A 23 PHE A 24	None	1.02A	1z11B-4igvA: undetectable	1z11B-4igvA: 16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z11_D_8MOD501_0 (CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 6)	4igv	KIROLA (Actinidia deliciosa)	5 / 10	PHE A 136 ASN A 38 ILE A 39 ILE A 23 PHE A 24	None	1.05A	1z11D-4igvA: undetectable	1z11D-4igvA: 16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZMB_A_PXBA692_1 (LACTOTRANSFERRIN)	4igv	KIROLA (Actinidia deliciosa)	3 / 3	PRO A 130 GLU A 121 TYR A 96	None	0.80A	2zmbA-4igvA: undetectable	2zmbA-4igvA: 18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L8L_B_DVAB8_0 (GRAMICIDIN D)	4igv	KIROLA (Actinidia deliciosa)	3 / 3	VAL A 103 VAL A 105 TRP A 116	None	0.69A	3l8lA-4igvA: undetectable 3l8lB-4igvA: undetectable	3l8lA-4igvA: 8.08 3l8lB-4igvA: 10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L8L_D_DVAD8_0 (GRAMICIDIN D)	4igv	KIROLA (Actinidia deliciosa)	3 / 3	VAL A 103 VAL A 105 TRP A 116	None	0.81A	3l8lC-4igvA: undetectable 3l8lD-4igvA: undetectable	3l8lC-4igvA: 8.08 3l8lD-4igvA: 10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OGC_B_TA1B601_1 (TUBULIN BETA CHAIN)	4igv	KIROLA (Actinidia deliciosa)	5 / 12	VAL A 127 GLU A 129 PHE A 99 PRO A 130 LEU A 133	None	1.19A	5ogcB-4igvA: undetectable	5ogcB-4igvA: 14.80

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1AV2_D_DVAD8_0","GRAMICIDIN A","4igv","KIROLA","Actinidia deliciosa",3,"VAL A 103;VAL A 105;TRP A 116","None","0.82A","1av2C-4igvA:undetectable;1av2D-4igvA:undetectable","1av2C-4igvA:8.08;1av2D-4igvA:8.08"],["1W5U_D_DVAD8_0","GRAMICIDIN D","4igv","KIROLA","Actinidia deliciosa",3,"VAL A 103;VAL A 105;TRP A 116","None","0.83A","1w5uC-4igvA:undetectable;1w5uD-4igvA:undetectable","1w5uC-4igvA:8.08;1w5uD-4igvA:8.08"],["1Z11_B_8MOB501_0","CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 6","4igv","KIROLA","Actinidia deliciosa",5,"PHE A 136;ASN A  38;ILE A  39;ILE A  23;PHE A  24","None","1.02A","1z11B-4igvA:undetectable","1z11B-4igvA:16.56"],["1Z11_D_8MOD501_0","CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 6","4igv","KIROLA","Actinidia deliciosa",5,"PHE A 136;ASN A  38;ILE A  39;ILE A  23;PHE A  24","None","1.05A","1z11D-4igvA:undetectable","1z11D-4igvA:16.56"],["2ZMB_A_PXBA692_1","LACTOTRANSFERRIN","4igv","KIROLA","Actinidia deliciosa",3,"PRO A 130;GLU A 121;TYR A  96","None","0.80A","2zmbA-4igvA:undetectable","2zmbA-4igvA:18.67"],["3L8L_B_DVAB8_0","GRAMICIDIN D","4igv","KIROLA","Actinidia deliciosa",3,"VAL A 103;VAL A 105;TRP A 116","None","0.69A","3l8lA-4igvA:undetectable;3l8lB-4igvA:undetectable","3l8lA-4igvA:8.08;3l8lB-4igvA:10.10"],["3L8L_D_DVAD8_0","GRAMICIDIN D","4igv","KIROLA","Actinidia deliciosa",3,"VAL A 103;VAL A 105;TRP A 116","None","0.81A","3l8lC-4igvA:undetectable;3l8lD-4igvA:undetectable","3l8lC-4igvA:8.08;3l8lD-4igvA:10.10"],["5OGC_B_TA1B601_1","TUBULIN BETA CHAIN","4igv","KIROLA","Actinidia deliciosa",5,"VAL A 127;GLU A 129;PHE A  99;PRO A 130;LEU A 133","None","1.19A","5ogcB-4igvA:undetectable","5ogcB-4igvA:14.80"]]