SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ihe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 11 TYR A 231
ASP A 224
TYR A 396
HIS A 255
ILE A 250
None
1.17A 1fkfA-4iheA:
undetectable
1fkfA-4iheA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
3 / 3 ALA A 158
VAL A 114
TRP A 117
None
0.96A 1tkqA-4iheA:
undetectable
1tkqA-4iheA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_0
(SAM DEPENDENT
METHYLTRANSFERASE)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 12 PHE A 326
ALA A 188
ALA A 282
GLY A  56
GLY A 187
None
1.12A 2igtA-4iheA:
undetectable
2igtA-4iheA:
27.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_0
(SAM DEPENDENT
METHYLTRANSFERASE)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 12 PHE A 326
ALA A 188
ALA A 282
GLY A  56
GLY A 187
None
1.11A 2igtB-4iheA:
undetectable
2igtB-4iheA:
27.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_B_D16B568_1
(THYMIDYLATE SYNTHASE)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 12 LEU A  86
ASP A  96
GLY A 124
PHE A 125
ALA A  67
None
1.08A 2kceB-4iheA:
undetectable
2kceB-4iheA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
6 / 12 GLY A 107
GLY A 185
GLY A  56
GLY A 103
THR A 186
ILE A 197
None
1.35A 2oxtA-4iheA:
undetectable
2oxtA-4iheA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 12 LEU A 213
GLY A 198
LEU A 100
VAL A  98
ALA A 375
None
1.24A 2vmyB-4iheA:
undetectable
2vmyB-4iheA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
4 / 8 GLN A 179
ARG A 370
GLY A 198
GLY A  30
None
0.80A 2y6rB-4iheA:
undetectable
2y6rB-4iheA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_0
(SAM DEPENDENT
METHYLTRANSFERASE)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 12 LEU A 143
GLY A  56
GLY A 102
PHE A 144
THR A 186
None
1.11A 3dh0B-4iheA:
undetectable
3dh0B-4iheA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 12 GLY A 386
GLY A 147
GLY A  52
ASP A  51
ARG A 155
None
0.96A 3huoB-4iheA:
undetectable
3huoB-4iheA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 12 VAL A 165
LEU A  61
ALA A 184
GLY A 112
LEU A 118
None
1.08A 3ln1A-4iheA:
undetectable
3ln1A-4iheA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 12 VAL A 165
LEU A  61
ALA A 184
GLY A 112
LEU A 118
None
1.08A 3ln1B-4iheA:
undetectable
3ln1B-4iheA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 12 VAL A 165
LEU A  61
ALA A 184
GLY A 112
LEU A 118
None
1.09A 3ln1D-4iheA:
undetectable
3ln1D-4iheA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T8N_D_EDTD135_0
(STEROID
DELTA-ISOMERASE)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 11 THR A 101
GLY A 102
PRO A 156
THR A 186
GLY A 183
None
1.39A 3t8nD-4iheA:
undetectable
3t8nF-4iheA:
undetectable
3t8nD-4iheA:
14.01
3t8nF-4iheA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T8N_D_EDTD135_0
(STEROID
DELTA-ISOMERASE)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 11 THR A 186
GLY A 183
THR A 101
GLY A 102
PRO A 156
None
1.39A 3t8nD-4iheA:
undetectable
3t8nF-4iheA:
undetectable
3t8nD-4iheA:
14.01
3t8nF-4iheA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 12 ALA A 278
GLY A 192
HIS A 389
ALA A 375
ASN A 281
None
1.18A 3tm4A-4iheA:
undetectable
3tm4A-4iheA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 12 ALA A 278
GLY A 192
HIS A 389
ALA A 375
ASN A 281
None
1.16A 3tm4B-4iheA:
undetectable
3tm4B-4iheA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
4 / 8 GLN A 179
ARG A 370
GLY A 198
GLY A  30
None
0.92A 3v3nB-4iheA:
undetectable
3v3nB-4iheA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
4 / 8 GLN A 179
ARG A 370
GLY A 198
GLY A  30
None
0.92A 3v3nC-4iheA:
undetectable
3v3nC-4iheA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_A_UEGA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 11 GLY A 161
ALA A 116
GLY A 113
VAL A 165
VAL A 138
None
1.25A 4c5lA-4iheA:
undetectable
4c5lA-4iheA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 9 GLY A 161
ALA A 116
GLY A 113
VAL A 165
VAL A 138
None
1.27A 4c5lB-4iheA:
undetectable
4c5lB-4iheA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_C_UEGC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 10 GLY A 161
ALA A 116
GLY A 113
VAL A 165
VAL A 138
None
1.34A 4c5lC-4iheA:
undetectable
4c5lC-4iheA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 10 GLY A 161
ALA A 116
GLY A 113
VAL A 165
VAL A 138
None
1.29A 4c5lD-4iheA:
undetectable
4c5lD-4iheA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 10 GLY A 161
ALA A 116
GLY A 113
VAL A 165
VAL A 138
None
1.34A 4c5nD-4iheA:
undetectable
4c5nD-4iheA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
4 / 8 GLY A 187
GLY A 183
ILE A 197
LEU A 100
None
0.73A 4mwzB-4iheA:
undetectable
4mwzB-4iheA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 12 LEU A 204
LEU A 213
GLY A 364
ALA A 362
LEU A 237
None
1.24A 4retA-4iheA:
undetectable
4retA-4iheA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 12 LEU A 204
LEU A 213
GLY A 364
ALA A 362
LEU A 237
None
1.24A 4retC-4iheA:
undetectable
4retC-4iheA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_A_15UA301_1
(THROMBIN HEAVY CHAIN)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 10 LEU A 146
LEU A 108
ALA A 141
ALA A 105
GLY A 102
None
1.23A 4rn6A-4iheA:
undetectable
4rn6A-4iheA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
4 / 8 ALA A 200
ALA A 375
ALA A 214
ALA A 212
None
0.75A 4twdF-4iheA:
undetectable
4twdG-4iheA:
undetectable
4twdH-4iheA:
undetectable
4twdI-4iheA:
undetectable
4twdJ-4iheA:
undetectable
4twdF-4iheA:
22.95
4twdG-4iheA:
22.95
4twdH-4iheA:
22.95
4twdI-4iheA:
22.95
4twdJ-4iheA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 12 VAL A  60
VAL A  43
LEU A  35
THR A 199
ALA A 212
None
1.33A 4yhaA-4iheA:
undetectable
4yhaA-4iheA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DX3_A_ESTA601_1
(ESTROGEN RECEPTOR)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 10 LEU A 213
ALA A 212
LEU A 368
GLY A 303
LEU A 301
None
1.30A 5dx3A-4iheA:
undetectable
5dx3A-4iheA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
4 / 6 GLU A 173
GLY A  40
ARG A 332
ARG A 123
None
1.10A 5jcnB-4iheA:
undetectable
5jcnB-4iheA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 12 ALA A 142
LEU A 100
ALA A 140
PHE A 106
GLY A 107
None
1.00A 5jglA-4iheA:
undetectable
5jglA-4iheA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 12 THR A  58
ALA A 375
GLY A 180
LEU A 377
ALA A 215
None
1.20A 5jglB-4iheA:
undetectable
5jglB-4iheA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM9_B_ADNB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 12 LEU A 213
ALA A 282
LEU A 309
HIS A 306
HIS A 317
None
1.19A 5km9B-4iheA:
undetectable
5km9B-4iheA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 12 GLY A  34
GLY A  30
VAL A 177
VAL A 367
HIS A 374
None
1.01A 5kocB-4iheA:
undetectable
5kocB-4iheA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 10 THR A 101
GLY A  56
GLY A 183
LEU A 160
ALA A 110
None
0.81A 5l0zB-4iheA:
undetectable
5l0zB-4iheA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 9 ALA A 215
THR A 283
ALA A 282
GLY A 195
ASP A 145
None
1.13A 5l5zK-4iheA:
undetectable
5l5zL-4iheA:
undetectable
5l5zK-4iheA:
20.34
5l5zL-4iheA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 11 THR A 283
ALA A 282
GLY A 196
GLY A 185
ALA A 184
None
0.91A 5lf3K-4iheA:
undetectable
5lf3L-4iheA:
undetectable
5lf3K-4iheA:
19.95
5lf3L-4iheA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 11 THR A 283
ALA A 282
GLY A 196
GLY A 185
ALA A 184
None
0.90A 5lf3Y-4iheA:
undetectable
5lf3Z-4iheA:
undetectable
5lf3Y-4iheA:
19.95
5lf3Z-4iheA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 11 THR A 283
ALA A 282
GLY A 196
GLY A 185
ALA A 184
None
0.94A 5lf7K-4iheA:
undetectable
5lf7L-4iheA:
undetectable
5lf7K-4iheA:
19.95
5lf7L-4iheA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 11 THR A 283
ALA A 282
GLY A 196
GLY A 185
ALA A 184
None
0.95A 5lf7Y-4iheA:
undetectable
5lf7Z-4iheA:
undetectable
5lf7Y-4iheA:
19.95
5lf7Z-4iheA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 11 THR A 283
ALA A 282
GLY A 196
GLY A 185
ALA A 184
None
0.87A 6hwdK-4iheA:
undetectable
6hwdL-4iheA:
undetectable
6hwdK-4iheA:
12.20
6hwdL-4iheA:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
4ihe THNT PROTEIN
(Streptomyces
cattleya)
5 / 11 THR A 283
ALA A 282
GLY A 196
GLY A 185
ALA A 184
None
0.87A 6hwdY-4iheA:
undetectable
6hwdZ-4iheA:
undetectable
6hwdY-4iheA:
12.20
6hwdZ-4iheA:
10.98