SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ii1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 4ii1 ZINC FINGER
CCCH-TYPE WITH G
PATCH
DOMAIN-CONTAINING
PROTEIN
(Homo
sapiens) 		3 / 3 CYH A 188
CYH A 194
HIS A 198
 ZN  A 901 (-2.4A)
ZN  A 901 (-2.2A)
ZN  A 901 (-3.2A)
 0.83A 2iwkA-4ii1A:
undetectable		 2iwkA-4ii1A:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 4ii1 ZINC FINGER
CCCH-TYPE WITH G
PATCH
DOMAIN-CONTAINING
PROTEIN
(Homo
sapiens) 		3 / 3 CYH A 188
CYH A 194
HIS A 198
 ZN  A 901 (-2.4A)
ZN  A 901 (-2.2A)
ZN  A 901 (-3.2A)
 0.80A 2iwkB-4ii1A:
undetectable		 2iwkB-4ii1A:
12.93