SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ii3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FCN_A_DVAA35_0
(UBIQUITIN)		 4ii3 UBIQUITIN-60S
RIBOSOMAL PROTEIN
L40
(Schizosaccharomy
ces
pombe) 		4 / 4 GLN B  31
GLU B  34
ILE B  36
PRO B  37
 None
 0.92A 2fcnA-4ii3B:
14.7		 2fcnA-4ii3B:
86.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FCN_B_DVAB35_0
(UBIQUITIN)		 4ii3 UBIQUITIN-60S
RIBOSOMAL PROTEIN
L40
(Schizosaccharomy
ces
pombe) 		4 / 6 GLN B  31
GLU B  34
ILE B  36
PRO B  37
 None
 0.38A 2fcnA-4ii3B:
14.7
2fcnB-4ii3B:
14.2		 2fcnA-4ii3B:
86.75
2fcnB-4ii3B:
86.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 4ii3 UBIQUITIN-60S
RIBOSOMAL PROTEIN
L40
(Schizosaccharomy
ces
pombe) 		5 / 11 THR B   9
ILE B  13
ILE B  36
VAL B  26
LEU B  43
 None
 1.17A 3a51A-4ii3B:
undetectable		 3a51A-4ii3B:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_C_VDYC6178_1
(VITAMIN D
HYDROXYLASE)		 4ii3 UBIQUITIN-60S
RIBOSOMAL PROTEIN
L40
(Schizosaccharomy
ces
pombe) 		5 / 12 THR B   9
ILE B  13
ILE B  36
VAL B  26
LEU B  43
 None
 1.13A 3a51C-4ii3B:
undetectable		 3a51C-4ii3B:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_E_VDYE6178_1
(VITAMIN D
HYDROXYLASE)		 4ii3 UBIQUITIN-60S
RIBOSOMAL PROTEIN
L40
(Schizosaccharomy
ces
pombe) 		5 / 12 THR B   9
ILE B  13
ILE B  36
VAL B  26
LEU B  43
 None
 1.14A 3a51E-4ii3B:
undetectable		 3a51E-4ii3B:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_B_TRUB800_1
(GLUTAMATE RECEPTOR 2)		 4ii3 UBIQUITIN-60S
RIBOSOMAL PROTEIN
L40
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU B  69
LEU B  15
ILE B  36
SER B  28
LYS B  27
 None
 1.50A 3iltB-4ii3B:
undetectable
3iltE-4ii3B:
undetectable		 3iltB-4ii3B:
20.66
3iltE-4ii3B:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4ii3 UBIQUITIN-60S
RIBOSOMAL PROTEIN
L40
(Schizosaccharomy
ces
pombe) 		4 / 7 ILE B  44
GLN B  49
ILE B  23
ASP B  52
 None
 0.75A 4w5oA-4ii3B:
undetectable		 4w5oA-4ii3B:
8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4ii3 UBIQUITIN-60S
RIBOSOMAL PROTEIN
L40
(Schizosaccharomy
ces
pombe) 		4 / 6 ILE B  44
GLN B  49
ILE B  23
ASP B  52
 None
 0.72A 4w5qA-4ii3B:
undetectable		 4w5qA-4ii3B:
8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4ii3 UBIQUITIN-60S
RIBOSOMAL PROTEIN
L40
(Schizosaccharomy
ces
pombe) 		4 / 6 ILE B  44
GLN B  49
ILE B  23
ASP B  52
 None
 0.91A 4w5tA-4ii3B:
undetectable		 4w5tA-4ii3B:
8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 4ii3 UBIQUITIN-60S
RIBOSOMAL PROTEIN
L40
(Schizosaccharomy
ces
pombe) 		4 / 6 ILE B  44
GLN B  49
ILE B  23
ASP B  52
 None
 0.77A 4z4cA-4ii3B:
undetectable		 4z4cA-4ii3B:
8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4ii3 UBIQUITIN-60S
RIBOSOMAL PROTEIN
L40
(Schizosaccharomy
ces
pombe) 		4 / 6 ILE B  44
GLN B  49
ILE B  23
ASP B  52
 None
 0.75A 4z4dA-4ii3B:
undetectable		 4z4dA-4ii3B:
8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4ii3 UBIQUITIN-60S
RIBOSOMAL PROTEIN
L40
(Schizosaccharomy
ces
pombe) 		4 / 7 ILE B  44
GLN B  49
ILE B  23
ASP B  52
 None
 0.76A 4z4eA-4ii3B:
undetectable		 4z4eA-4ii3B:
8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4ii3 UBIQUITIN-60S
RIBOSOMAL PROTEIN
L40
(Schizosaccharomy
ces
pombe) 		4 / 7 ILE B  44
GLN B  49
ILE B  23
ASP B  52
 None
 0.75A 4z4gA-4ii3B:
undetectable		 4z4gA-4ii3B:
8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA903_0
(PROTEIN ARGONAUTE-2)		 4ii3 UBIQUITIN-60S
RIBOSOMAL PROTEIN
L40
(Schizosaccharomy
ces
pombe) 		4 / 6 ILE B  44
GLN B  49
ILE B  23
ASP B  52
 None
 0.85A 6cbdA-4ii3B:
undetectable		 6cbdA-4ii3B:
8.06