SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ij2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 4ij2 IRON-REGULATED
SURFACE DETERMINANT
PROTEIN H
(Staphylococcus
aureus) 		4 / 8 ASN E 613
THR E 588
ASP E 566
ASP E 590
 None
 1.03A 1bu5B-4ij2E:
undetectable		 1bu5B-4ij2E:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4ij2 IRON-REGULATED
SURFACE DETERMINANT
PROTEIN H
(Staphylococcus
aureus) 		5 / 12 ILE E 424
ALA E 326
ILE E 437
PHE E 399
LEU E 330
 None
 1.02A 3dzuA-4ij2E:
undetectable		 3dzuA-4ij2E:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_1
(MODIFICATION
METHYLASE HHAI)		 4ij2 IRON-REGULATED
SURFACE DETERMINANT
PROTEIN H
(Staphylococcus
aureus) 		3 / 3 GLU E 559
SER E 563
VAL E 564
 None
 0.78A 3eeoA-4ij2E:
undetectable		 3eeoA-4ij2E:
24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_2
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT)		 4ij2 IRON-REGULATED
SURFACE DETERMINANT
PROTEIN H
(Staphylococcus
aureus) 		4 / 5 TYR E 484
GLN E 493
ILE E 598
LEU E 490
 None
 1.25A 3ls4L-4ij2E:
4.0		 3ls4L-4ij2E:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4ij2 IRON-REGULATED
SURFACE DETERMINANT
PROTEIN H
(Staphylococcus
aureus) 		4 / 7 GLU E 498
GLU E 496
GLU E 491
ARG E 492
 None
 1.18A 4mi4B-4ij2E:
undetectable
4mi4C-4ij2E:
undetectable		 4mi4B-4ij2E:
18.29
4mi4C-4ij2E:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_2
(SCRFP-TAG,GP41)		 4ij2 IRON-REGULATED
SURFACE DETERMINANT
PROTEIN H
(Staphylococcus
aureus) 		3 / 3 LYS E 397
TRP E 396
SER E 329
 None
 1.29A 5nwwA-4ij2E:
undetectable		 5nwwA-4ij2E:
8.70