SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ij4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 4ij4 CHITINASE A
(Gemmabryum
coronatum) 		4 / 7 SER A 102
TYR A 105
ASN A 104
TYR A 107
 NAG  A 303 (-3.5A)
EDO  A 308 (-3.6A)
EDO  A 307 ( 4.5A)
None
 1.01A 1dssG-4ij4A:
undetectable		 1dssG-4ij4A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 4ij4 CHITINASE A
(Gemmabryum
coronatum) 		4 / 8 SER A 102
TYR A 105
ASN A 104
TYR A 107
 NAG  A 303 (-3.5A)
EDO  A 308 (-3.6A)
EDO  A 307 ( 4.5A)
None
 1.01A 1dssR-4ij4A:
undetectable		 1dssR-4ij4A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_1
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)		 4ij4 CHITINASE A
(Gemmabryum
coronatum) 		5 / 12 PHE A  54
GLY A  95
GLY A 111
LEU A 118
LEU A 116
 None
 1.04A 2hw2A-4ij4A:
undetectable		 2hw2A-4ij4A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1498_1
(CYTOCHROME P450 3A4)		 4ij4 CHITINASE A
(Gemmabryum
coronatum) 		5 / 12 SER A  62
LEU A  28
PHE A  12
ILE A  58
THR A 135
 None
 1.02A 2v0mC-4ij4A:
undetectable		 2v0mC-4ij4A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1498_1
(CYTOCHROME P450 3A4)		 4ij4 CHITINASE A
(Gemmabryum
coronatum) 		5 / 12 SER A  62
PHE A  12
ILE A  58
ALA A 136
THR A 135
 None
 1.03A 2v0mC-4ij4A:
undetectable		 2v0mC-4ij4A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 4ij4 CHITINASE A
(Gemmabryum
coronatum) 		4 / 8 SER A 102
TYR A 105
ASN A 104
TYR A 107
 NAG  A 303 (-3.5A)
EDO  A 308 (-3.6A)
EDO  A 307 ( 4.5A)
None
 1.02A 3dmtC-4ij4A:
undetectable		 3dmtC-4ij4A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_1
(CYTOCHROME P450 3A4)		 4ij4 CHITINASE A
(Gemmabryum
coronatum) 		5 / 12 SER A  62
PHE A  12
ILE A  58
ALA A 136
ALA A 126
 None
 1.02A 3nxuA-4ij4A:
undetectable		 3nxuA-4ij4A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_1
(CYTOCHROME P450 3A4)		 4ij4 CHITINASE A
(Gemmabryum
coronatum) 		5 / 12 SER A  62
PHE A  12
ILE A  58
ALA A 136
ALA A 126
 None
 1.01A 3nxuB-4ij4A:
undetectable		 3nxuB-4ij4A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3A_A_TACA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 4ij4 CHITINASE A
(Gemmabryum
coronatum) 		5 / 12 LEU A  28
SER A  30
ASN A  33
PRO A   9
SER A   2
 None
 1.19A 4b3aA-4ij4A:
undetectable		 4b3aA-4ij4A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_D_READ602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 4ij4 CHITINASE A
(Gemmabryum
coronatum) 		5 / 12 ILE A 160
GLY A 158
CYH A 192
THR A 189
LEU A 203
 None
 1.25A 5fhzD-4ij4A:
undetectable		 5fhzD-4ij4A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_1
(CYTOCHROME P450 3A4)		 4ij4 CHITINASE A
(Gemmabryum
coronatum) 		5 / 12 PHE A  12
ILE A  58
ALA A 136
THR A 135
ALA A 126
 None
 1.10A 5vceA-4ij4A:
0.4		 5vceA-4ij4A:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_1
(CYTOCHROME P450 3A5)		 4ij4 CHITINASE A
(Gemmabryum
coronatum) 		6 / 12 SER A  62
PHE A  12
ILE A  58
ALA A 136
THR A 135
ALA A 126
 None
 1.26A 5veuA-4ij4A:
undetectable		 5veuA-4ij4A:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_B_RITB602_1
(CYTOCHROME P450 3A5)		 4ij4 CHITINASE A
(Gemmabryum
coronatum) 		6 / 12 SER A  62
PHE A  12
ILE A  58
ALA A 136
THR A 135
ALA A 126
 None
 1.13A 5veuB-4ij4A:
undetectable		 5veuB-4ij4A:
17.23