SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ij5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 4ij5 PHOSPHOSERINE
PHOSPHATASE 1
(Hydrogenobacter
thermophilus) 		4 / 5 GLU A  82
SER A  54
PRO A 153
SER A 149
 None
 1.48A 4k17B-4ij5A:
undetectable		 4k17B-4ij5A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 4ij5 PHOSPHOSERINE
PHOSPHATASE 1
(Hydrogenobacter
thermophilus) 		3 / 3 GLY A  32
GLU A  65
THR A  62
 None
 0.57A 4kouA-4ij5A:
undetectable		 4kouA-4ij5A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4ij5 PHOSPHOSERINE
PHOSPHATASE 1
(Hydrogenobacter
thermophilus) 		4 / 6 ASP A 175
ALA A 177
THR A 197
TYR A 204
 None
 1.23A 4w5qA-4ij5A:
undetectable		 4w5qA-4ij5A:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4ij5 PHOSPHOSERINE
PHOSPHATASE 1
(Hydrogenobacter
thermophilus) 		4 / 6 ASP A 175
ALA A 177
THR A 197
TYR A 204
 None
 1.24A 4w5rA-4ij5A:
2.0		 4w5rA-4ij5A:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4ij5 PHOSPHOSERINE
PHOSPHATASE 1
(Hydrogenobacter
thermophilus) 		4 / 6 ASP A 175
ALA A 177
THR A 197
TYR A 204
 None
 1.21A 4w5tA-4ij5A:
2.0		 4w5tA-4ij5A:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 4ij5 PHOSPHOSERINE
PHOSPHATASE 1
(Hydrogenobacter
thermophilus) 		4 / 8 GLY A  22
GLN A  21
SER A  54
HIS A 150
 None
CL  A 301 (-4.0A)
None
None
 0.98A 4wryA-4ij5A:
undetectable		 4wryA-4ij5A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 4ij5 PHOSPHOSERINE
PHOSPHATASE 1
(Hydrogenobacter
thermophilus) 		4 / 6 ASP A 175
ALA A 177
THR A 197
TYR A 204
 None
 1.20A 4z4cA-4ij5A:
undetectable		 4z4cA-4ij5A:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4ij5 PHOSPHOSERINE
PHOSPHATASE 1
(Hydrogenobacter
thermophilus) 		4 / 6 ASP A 175
ALA A 177
THR A 197
TYR A 204
 None
 1.23A 4z4fA-4ij5A:
undetectable		 4z4fA-4ij5A:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4ij5 PHOSPHOSERINE
PHOSPHATASE 1
(Hydrogenobacter
thermophilus) 		4 / 5 ASP A 175
ALA A 177
THR A 197
TYR A 204
 None
 1.23A 4z4gA-4ij5A:
2.1		 4z4gA-4ij5A:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4ij5 PHOSPHOSERINE
PHOSPHATASE 1
(Hydrogenobacter
thermophilus) 		4 / 6 ASP A 175
ALA A 177
THR A 197
TYR A 204
 None
 1.23A 4z4iA-4ij5A:
2.1		 4z4iA-4ij5A:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_ACTA608_0
(SERUM ALBUMIN)		 4ij5 PHOSPHOSERINE
PHOSPHATASE 1
(Hydrogenobacter
thermophilus) 		3 / 3 LYS A 138
ARG A 139
HIS A 140
 None
 1.25A 4zbrA-4ij5A:
undetectable		 4zbrA-4ij5A:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_2
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 4ij5 PHOSPHOSERINE
PHOSPHATASE 1
(Hydrogenobacter
thermophilus) 		3 / 3 VAL A 136
ARG A   8
PRO A 153
 None
CL  A 301 (-4.2A)
None
 0.74A 5koxA-4ij5A:
undetectable		 5koxA-4ij5A:
17.39