SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ijd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4ijd HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9
(Homo
sapiens) 		5 / 11 ILE A 253
ALA A 256
GLY A 257
GLY A 290
ASN A 320
 None
 0.66A 4e47A-4ijdA:
6.4		 4e47A-4ijdA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4ijd HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9
(Homo
sapiens) 		5 / 11 ILE A 253
ALA A 256
GLY A 257
GLY A 290
ASN A 320
 None
 0.65A 4e47B-4ijdA:
7.2		 4e47B-4ijdA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_C_SAMC800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4ijd HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9
(Homo
sapiens) 		5 / 11 ILE A 253
ALA A 256
GLY A 257
GLY A 290
ASN A 320
 None
 0.63A 4e47C-4ijdA:
undetectable		 4e47C-4ijdA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4ijd HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9
(Homo
sapiens) 		5 / 11 ILE A 253
ALA A 256
GLY A 257
GLY A 290
ASN A 320
 None
 0.65A 4jdsA-4ijdA:
8.6		 4jdsA-4ijdA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4ijd HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9
(Homo
sapiens) 		5 / 11 ILE A 253
ALA A 256
GLY A 257
GLY A 290
ASN A 320
 None
 0.66A 4jdsB-4ijdA:
8.5		 4jdsB-4ijdA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_C_SAMC401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4ijd HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9
(Homo
sapiens) 		5 / 11 ILE A 253
ALA A 256
GLY A 257
GLY A 290
ASN A 320
 None
 0.63A 4jdsC-4ijdA:
undetectable		 4jdsC-4ijdA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4ijd HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9
(Homo
sapiens) 		5 / 12 ILE A 253
ALA A 256
GLY A 257
GLY A 290
ASN A 320
 None
 0.73A 4jlgA-4ijdA:
6.2		 4jlgA-4ijdA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4ijd HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9
(Homo
sapiens) 		5 / 11 ILE A 253
ALA A 256
GLY A 257
GLY A 290
ASN A 320
 None
 0.67A 5ayfA-4ijdA:
8.7		 5ayfA-4ijdA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_B_SALB203_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 4ijd HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9
(Homo
sapiens) 		4 / 6 PRO A 243
GLY A 245
LEU A 267
VAL A 225
 None
UNX  A 507 ( 4.0A)
None
None
 0.83A 5x80A-4ijdA:
undetectable
5x80B-4ijdA:
undetectable		 5x80A-4ijdA:
19.81
5x80B-4ijdA:
19.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6NM4_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 4ijd HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9
(Homo
sapiens) 		7 / 7 ALA A 256
GLY A 257
LEU A 258
GLY A 290
TYR A 291
ASN A 320
CYH A 321
 None
 0.46A 6nm4A-4ijdA:
32.7		 6nm4A-4ijdA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6NM4_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 4ijd HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9
(Homo
sapiens) 		9 / 9 ILE A 253
ALA A 256
GLY A 257
LEU A 258
GLY A 290
TYR A 291
ASN A 320
CYH A 321
ARG A 323
 None
 0.56A 6nm4B-4ijdA:
32.6		 6nm4B-4ijdA:
100.00