SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ikb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2887_1
(AMINOMETHYLTRANSFERA
SE)		 4ikb SORTING NEXIN-11
(Homo
sapiens) 		3 / 3 ASP B  93
GLU B  29
ARG B  57
 None
 0.87A 1wopA-4ikbB:
undetectable		 1wopA-4ikbB:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4ikb SORTING NEXIN-11
(Homo
sapiens) 		4 / 7 ILE B  40
LEU B 126
ARG B  59
LEU B  66
 None
None
SO4  B 201 (-3.7A)
None
 0.97A 3ag3A-4ikbB:
undetectable
3ag3J-4ikbB:
undetectable		 3ag3A-4ikbB:
14.82
3ag3J-4ikbB:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 4ikb SORTING NEXIN-11
(Homo
sapiens) 		4 / 7 VAL B 132
ILE B 135
LEU B 116
LEU B 122
 None
 0.94A 4l1wA-4ikbB:
undetectable		 4l1wA-4ikbB:
18.46