SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ikh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		5 / 12 LEU A  94
LEU A 104
ILE A  36
ARG A 221
ILE A  74
 None
 1.24A 1tw4B-4ikhA:
undetectable		 1tw4B-4ikhA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		4 / 6 TRP A 189
LEU A 119
LEU A  94
PRO A 188
 GSH  A 303 (-4.3A)
None
None
None
 1.21A 2dqyC-4ikhA:
undetectable		 2dqyC-4ikhA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2001_1
(SERUM ALBUMIN)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		5 / 12 MET A  37
ILE A 174
HIS A 167
TYR A 179
GLY A 176
 None
 1.47A 2vufA-4ikhA:
2.7		 2vufA-4ikhA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_1
(2'-O-METHYL
TRANSFERASE)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		3 / 3 TYR A  96
ASP A  82
ASP A  76
 None
 0.83A 3r24A-4ikhA:
undetectable		 3r24A-4ikhA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ0_X_DXCX75_0
(CYTOCHROME C7)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		4 / 7 ILE A 126
LYS A 212
PHE A 208
GLY A 204
 None
 1.07A 3sj0X-4ikhA:
undetectable		 3sj0X-4ikhA:
13.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MF6_A_BEZA303_0
(GLUTATHIONE
S-TRANSFERASE DOMAIN)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		5 / 5 THR A  28
PRO A  29
PHE A 139
ASN A 192
TYR A 197
 GSH  A 301 (-3.4A)
None
None
None
None
 0.34A 4mf6A-4ikhA:
36.3		 4mf6A-4ikhA:
68.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		4 / 7 LEU A  23
PRO A 231
LEU A  38
GLU A  39
 None
 0.96A 4z4fA-4ikhA:
undetectable		 4z4fA-4ikhA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		5 / 9 ALA A 157
LEU A 164
GLY A 162
LEU A 161
LEU A 193
 None
 1.11A 5dqfA-4ikhA:
2.7		 5dqfA-4ikhA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		5 / 12 GLY A 134
GLY A 131
ASP A 165
VAL A 211
ILE A 205
 None
GSH  A 303 (-3.3A)
None
None
None
 0.90A 5eifC-4ikhA:
undetectable		 5eifC-4ikhA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		5 / 12 GLY A 134
GLY A 131
ASP A 165
VAL A 211
ILE A 205
 None
GSH  A 303 (-3.3A)
None
None
None
 0.90A 5ikmA-4ikhA:
undetectable		 5ikmA-4ikhA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		5 / 12 GLY A 134
GLY A 131
ASP A 165
VAL A 211
ILE A 205
 None
GSH  A 303 (-3.3A)
None
None
None
 0.90A 5kqrA-4ikhA:
undetectable		 5kqrA-4ikhA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		5 / 12 GLY A 134
GLY A 131
ASP A 165
VAL A 211
ILE A 205
 None
GSH  A 303 (-3.3A)
None
None
None
 0.89A 5kqsA-4ikhA:
undetectable		 5kqsA-4ikhA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		5 / 12 GLY A 134
GLY A 131
ASP A 165
VAL A 211
ILE A 205
 None
GSH  A 303 (-3.3A)
None
None
None
 0.92A 5m5bA-4ikhA:
undetectable		 5m5bA-4ikhA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_A_SAMA301_0
(NS5)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		5 / 12 GLY A 134
GLY A 131
ASP A 165
VAL A 211
ILE A 205
 None
GSH  A 303 (-3.3A)
None
None
None
 0.88A 5njvA-4ikhA:
undetectable		 5njvA-4ikhA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_B_SAMB301_0
(NS5)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		5 / 12 GLY A 134
GLY A 131
ASP A 165
VAL A 211
ILE A 205
 None
GSH  A 303 (-3.3A)
None
None
None
 0.86A 5njvB-4ikhA:
undetectable		 5njvB-4ikhA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		4 / 7 LEU A  23
PRO A 231
LEU A  38
GLU A  39
 None
 1.02A 5t7bA-4ikhA:
undetectable		 5t7bA-4ikhA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		5 / 12 TYR A 197
LEU A 193
GLY A 131
ILE A 190
GLY A 127
 None
None
GSH  A 303 (-3.3A)
None
GSH  A 303 (-3.8A)
 0.81A 5wyqB-4ikhA:
undetectable		 5wyqB-4ikhA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		5 / 12 GLY A 134
GLY A 131
ASP A 165
VAL A 211
ILE A 205
 None
GSH  A 303 (-3.3A)
None
None
None
 0.87A 5wz1A-4ikhA:
undetectable		 5wz1A-4ikhA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		5 / 12 GLY A 134
GLY A 131
ASP A 165
VAL A 211
ILE A 205
 None
GSH  A 303 (-3.3A)
None
None
None
 0.87A 5wz1B-4ikhA:
undetectable		 5wz1B-4ikhA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		5 / 12 GLY A 134
GLY A 131
ASP A 165
VAL A 211
ILE A 205
 None
GSH  A 303 (-3.3A)
None
None
None
 0.86A 5wz1C-4ikhA:
undetectable		 5wz1C-4ikhA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		5 / 12 GLY A 134
GLY A 131
ASP A 165
VAL A 211
ILE A 205
 None
GSH  A 303 (-3.3A)
None
None
None
 0.84A 5wz1D-4ikhA:
undetectable		 5wz1D-4ikhA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		5 / 12 GLY A 134
GLY A 131
ASP A 165
VAL A 211
ILE A 205
 None
GSH  A 303 (-3.3A)
None
None
None
 0.87A 5wz1E-4ikhA:
undetectable		 5wz1E-4ikhA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		5 / 12 GLY A 134
GLY A 131
ASP A 165
VAL A 211
ILE A 205
 None
GSH  A 303 (-3.3A)
None
None
None
 0.85A 5wz1F-4ikhA:
undetectable		 5wz1F-4ikhA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		5 / 12 GLY A 134
GLY A 131
ASP A 165
VAL A 211
ILE A 205
 None
GSH  A 303 (-3.3A)
None
None
None
 0.88A 5wz1G-4ikhA:
undetectable		 5wz1G-4ikhA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		5 / 12 GLY A 134
GLY A 131
ASP A 165
VAL A 211
ILE A 205
 None
GSH  A 303 (-3.3A)
None
None
None
 0.85A 5wz1H-4ikhA:
undetectable		 5wz1H-4ikhA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA901_0
(MRNA CAPPING ENZYME
P5)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		5 / 11 VAL A 133
GLY A 134
ALA A 199
LEU A 193
ASN A 192
 None
 1.14A 5x6yA-4ikhA:
undetectable		 5x6yA-4ikhA:
15.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC901_0
(MRNA CAPPING ENZYME
P5)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		5 / 11 VAL A 133
GLY A 134
ALA A 199
LEU A 193
ASN A 192
 None
 1.13A 5x6yC-4ikhA:
undetectable		 5x6yC-4ikhA:
15.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA807_0
(GEPHYRIN)		 4ikh GLUTATHIONE
S-TRANSFERASE
(Pseudomonas
protegens) 		4 / 4 PRO A 231
LEU A  23
VAL A  50
ARG A  49
 None
 1.33A 6fgdA-4ikhA:
2.2		 6fgdA-4ikhA:
21.88