SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ilf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_C_ESTC353_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 4ilf THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBC
(Salmonella
enterica) 		5 / 12 VAL A  36
LEU A  67
GLY A  49
PRO A  50
VAL A 186
 None
 1.20A 1fduC-4ilfA:
undetectable		 1fduC-4ilfA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 4ilf THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBC
(Salmonella
enterica) 		4 / 5 VAL A  62
THR A  63
VAL A  36
GLY A  49
 None
 1.14A 2p2fA-4ilfA:
undetectable		 2p2fA-4ilfA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_B_ACTB653_0
(ACETYL-COENZYME A
SYNTHETASE)		 4ilf THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBC
(Salmonella
enterica) 		4 / 4 VAL A  62
THR A  63
VAL A  36
GLY A  49
 None
 1.15A 2p2fB-4ilfA:
undetectable		 2p2fB-4ilfA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 4ilf THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBC
(Salmonella
enterica) 		4 / 7 ASP A  95
PHE A 123
GLY A 127
THR A  97
 None
 1.15A 3vnsA-4ilfA:
undetectable		 3vnsA-4ilfA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		 4ilf THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBC
(Salmonella
enterica) 		5 / 11 TYR A 120
VAL A  92
ILE A  90
MET A 202
LEU A 206
 None
 1.13A 4lhmA-4ilfA:
undetectable		 4lhmA-4ilfA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C6P_A_4YHA601_1
(PROTEIN C)		 4ilf THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBC
(Salmonella
enterica) 		4 / 6 SER A 138
GLN A 131
SER A 130
ASP A  95
 None
 1.19A 5c6pA-4ilfA:
undetectable		 5c6pA-4ilfA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4ilf THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBC
(Salmonella
enterica) 		5 / 12 GLY A 155
ILE A 116
GLY A 198
HIS A 102
PHE A 149
 None
 1.30A 5eslA-4ilfA:
undetectable		 5eslA-4ilfA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_A_SAMA501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 4ilf THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBC
(Salmonella
enterica) 		5 / 11 LEU A 177
GLY A  35
LEU A  71
THR A  63
GLN A  20
 None
 1.02A 5o96A-4ilfA:
undetectable
5o96B-4ilfA:
2.2		 5o96A-4ilfA:
23.44
5o96B-4ilfA:
23.44