SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ilg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 4ilg A1 CISTRON-SPLICING
FACTOR AAR2
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 183
MET A 209
LEU A 268
LEU A 264
PHE A 221
 None
 1.13A 1dtlA-4ilgA:
undetectable		 1dtlA-4ilgA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JQD_A_HSMA600_1
(HISTAMINE
N-METHYLTRANSFERASE)		 4ilg A1 CISTRON-SPLICING
FACTOR AAR2
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 214
GLU A 223
GLN A 242
VAL A 180
 None
 1.22A 1jqdA-4ilgA:
undetectable		 1jqdA-4ilgA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		 4ilg A1 CISTRON-SPLICING
FACTOR AAR2
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 247
CYH A 292
LEU A 317
LEU A 316
LEU A 284
 None
 1.16A 2bxfA-4ilgA:
undetectable		 2bxfA-4ilgA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EFJ_A_37TA502_1
(3,7-DIMETHYLXANTHINE
METHYLTRANSFERASE)		 4ilg A1 CISTRON-SPLICING
FACTOR AAR2
(Saccharomyces
cerevisiae) 		5 / 12 TYR A 313
HIS A 244
TRP A 289
ILE A 247
ILE A 272
 None
 1.26A 2efjA-4ilgA:
undetectable		 2efjA-4ilgA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_B_SALB1304_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4ilg A1 CISTRON-SPLICING
FACTOR AAR2
(Saccharomyces
cerevisiae) 		5 / 10 ILE A  33
GLY A  32
PHE A   6
PHE A  46
ILE A  15
 None
 1.19A 2y7kB-4ilgA:
undetectable		 2y7kB-4ilgA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 4ilg A1 CISTRON-SPLICING
FACTOR AAR2
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 222
ASN A 216
TYR A 220
ILE A 267
LEU A 224
 None
 1.22A 4xj7A-4ilgA:
undetectable
4xj7B-4ilgA:
undetectable		 4xj7A-4ilgA:
16.67
4xj7B-4ilgA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HUA_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 4ilg A1 CISTRON-SPLICING
FACTOR AAR2
(Saccharomyces
cerevisiae) 		5 / 11 PHE A 234
VAL A  43
ILE A  44
PHE A 137
PHE A  46
 None
 1.42A 5huaA-4ilgA:
undetectable		 5huaA-4ilgA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_ACTA405_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 4ilg A1 CISTRON-SPLICING
FACTOR AAR2
(Saccharomyces
cerevisiae) 		3 / 3 GLN A  19
THR A 113
ASP A 111
 None
 0.76A 5k9dA-4ilgA:
undetectable		 5k9dA-4ilgA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 4ilg A1 CISTRON-SPLICING
FACTOR AAR2
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 205
TYR A 204
LEU A 210
TYR A 220
 None
 1.48A 5ki6A-4ilgA:
undetectable		 5ki6A-4ilgA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4ilg A1 CISTRON-SPLICING
FACTOR AAR2
(Saccharomyces
cerevisiae) 		4 / 4 GLN A 242
THR A 179
LEU A 205
LEU A 249
 None
 1.31A 5m5kB-4ilgA:
undetectable		 5m5kB-4ilgA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GSD_A_STRA401_0
(PROGESTERONE
5-BETA-REDUCTASE)		 4ilg A1 CISTRON-SPLICING
FACTOR AAR2
(Saccharomyces
cerevisiae) 		5 / 12 VAL A   4
ILE A  36
MET A 123
VAL A  43
ILE A  17
 None
 1.46A 6gsdA-4ilgA:
undetectable		 6gsdA-4ilgA:
12.57