SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ilq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S3Z_B_RIOB501_0
(AMINOGLYCOSIDE
6'-N-ACETYLTRANSFERA
SE)		 4ilq CT771
(Chlamydia
trachomatis) 		4 / 8 GLU A   7
VAL A  90
HIS A  33
ASP A  84
 SO4  A 201 ( 4.3A)
None
None
None
 1.25A 1s3zA-4ilqA:
undetectable
1s3zB-4ilqA:
undetectable		 1s3zA-4ilqA:
22.56
1s3zB-4ilqA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4ilq CT771
(Chlamydia
trachomatis) 		3 / 3 SER A 145
GLN A 144
PHE A 148
 None
 0.75A 3g4lC-4ilqA:
undetectable		 3g4lC-4ilqA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_B_NCAB1536_0
(DIPHTHERIA TOXIN)		 4ilq CT771
(Chlamydia
trachomatis) 		4 / 5 HIS A  45
GLY A  44
TYR A   8
GLU A  93
 SO4  A 201 ( 4.2A)
SO4  A 201 (-3.2A)
None
None
 1.32A 4ae1B-4ilqA:
undetectable		 4ae1B-4ilqA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_A_ADNA301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 4ilq CT771
(Chlamydia
trachomatis) 		5 / 9 PRO A  14
GLY A  67
ILE A  31
VAL A  61
THR A  64
 None
 1.28A 4x3mA-4ilqA:
undetectable		 4x3mA-4ilqA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_A_ADNA301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 4ilq CT771
(Chlamydia
trachomatis) 		5 / 9 PRO A  52
GLY A  44
ILE A  75
VAL A  94
THR A  95
 None
SO4  A 201 (-3.2A)
None
None
None
 1.41A 4x3mA-4ilqA:
undetectable		 4x3mA-4ilqA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_B_ADNB301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 4ilq CT771
(Chlamydia
trachomatis) 		5 / 9 PRO A  14
GLY A  67
ILE A  31
VAL A  61
THR A  64
 None
 1.26A 4x3mB-4ilqA:
undetectable		 4x3mB-4ilqA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)		 4ilq CT771
(Chlamydia
trachomatis) 		3 / 3 TRP A 117
ARG A  16
LEU A  60
 None
 0.94A 5dbyA-4ilqA:
undetectable		 5dbyA-4ilqA:
14.21