SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4im7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_A_SAMA105_0
(PROTEIN (MET
REPRESSOR))		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 8 GLU A 165
ARG A 169
LEU A 110
GLU A 107
 None
 0.94A 1cmaA-4im7A:
undetectable
1cmaB-4im7A:
undetectable		 1cmaA-4im7A:
11.27
1cmaB-4im7A:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_C_ACTC3004_0
(BETA-CARBONIC
ANHYDRASE)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 6 TYR A  77
ASP A  43
VAL A  95
GLY A  39
 None
 1.18A 1ekjC-4im7A:
2.7
1ekjD-4im7A:
1.9		 1ekjC-4im7A:
18.86
1ekjD-4im7A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_C_ACTC3007_0
(BETA-CARBONIC
ANHYDRASE)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 6 ASP A  43
VAL A  95
GLY A  39
TYR A  77
 None
 1.18A 1ekjC-4im7A:
2.1
1ekjD-4im7A:
1.9		 1ekjC-4im7A:
18.86
1ekjD-4im7A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 7 GLY A 129
HIS A 132
THR A 160
ILE A 125
 NAI  A 502 (-3.6A)
None
None
NAI  A 502 (-3.7A)
 0.98A 1gtnF-4im7A:
undetectable
1gtnG-4im7A:
undetectable		 1gtnF-4im7A:
9.09
1gtnG-4im7A:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 7 GLY A 129
HIS A 132
THR A 160
ILE A 125
 NAI  A 502 (-3.6A)
None
None
NAI  A 502 (-3.7A)
 0.96A 1gtnJ-4im7A:
undetectable
1gtnK-4im7A:
undetectable		 1gtnJ-4im7A:
9.09
1gtnK-4im7A:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		5 / 11 LEU A 106
ALA A 148
VAL A 109
LEU A  60
GLN A 102
 None
 1.17A 1kt6A-4im7A:
undetectable		 1kt6A-4im7A:
17.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M2W_A_MTLA5600_0
(MANNITOL
DEHYDROGENASE)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		7 / 9 ASN A 185
ASP A 224
LYS A 289
LEU A 293
ASN A 294
HIS A 297
LYS A 374
 NAI  A 502 ( 3.3A)
CS2  A 501 (-3.6A)
CS2  A 501 (-2.7A)
CS2  A 501 ( 4.5A)
CS2  A 501 (-3.0A)
CS2  A 501 (-3.7A)
CS2  A 501 (-2.8A)
 0.49A 1m2wA-4im7A:
51.6		 1m2wA-4im7A:
38.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M2W_B_MTLB6600_0
(MANNITOL
DEHYDROGENASE)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		7 / 9 ASN A 185
ASP A 224
LYS A 289
LEU A 293
ASN A 294
HIS A 297
LYS A 374
 NAI  A 502 ( 3.3A)
CS2  A 501 (-3.6A)
CS2  A 501 (-2.7A)
CS2  A 501 ( 4.5A)
CS2  A 501 (-3.0A)
CS2  A 501 (-3.7A)
CS2  A 501 (-2.8A)
 0.51A 1m2wB-4im7A:
51.9		 1m2wB-4im7A:
38.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_D_DIFD3701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		5 / 10 VAL A 441
LEU A 444
VAL A 400
GLY A 402
ALA A 401
 None
 1.18A 1pxxD-4im7A:
undetectable		 1pxxD-4im7A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		5 / 12 LEU A 300
LEU A 303
LEU A 306
ALA A 307
GLU A 412
 None
 1.02A 1s9pC-4im7A:
undetectable		 1s9pC-4im7A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 6 MET A 404
MET A 379
VAL A 383
LEU A 380
 None
 1.19A 1x8vA-4im7A:
1.6		 1x8vA-4im7A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		5 / 12 GLY A 295
SER A 382
HIS A 386
LEU A 337
LEU A 351
 None
 1.42A 1zgyA-4im7A:
undetectable		 1zgyA-4im7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_A_GBNA502_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 8 GLY A 161
THR A 160
ALA A 159
VAL A  26
 None
None
NAI  A 502 ( 4.7A)
None
 0.88A 2a1hA-4im7A:
undetectable
2a1hB-4im7A:
undetectable		 2a1hA-4im7A:
21.24
2a1hB-4im7A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_F_SAMF301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		5 / 12 LEU A 106
LEU A 110
GLY A 161
ASP A 149
ALA A 159
 None
None
None
None
NAI  A 502 ( 4.7A)
 1.07A 2bm9F-4im7A:
3.2		 2bm9F-4im7A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2002_1
(SERUM ALBUMIN)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 8 ARG A 268
ALA A 274
LYS A 273
GLU A 272
 None
 0.88A 2bxgA-4im7A:
undetectable		 2bxgA-4im7A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0D_A_ERYA1498_0
(CYTOCHROME P450 3A4)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		5 / 12 ILE A 427
ILE A 447
PHE A 451
ALA A 446
ALA A 439
 None
 1.12A 2j0dA-4im7A:
undetectable		 2j0dA-4im7A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_B_CLUB809_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 6 ALA A 301
TYR A 302
MET A 379
HIS A 297
 None
None
None
CS2  A 501 (-3.7A)
 1.27A 2pncB-4im7A:
undetectable		 2pncB-4im7A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		5 / 12 ILE A  25
ALA A 119
PHE A 264
ALA A 266
CYH A 183
 None
 1.08A 3dzyA-4im7A:
undetectable		 3dzyA-4im7A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 7 TYR A 347
MET A 288
ASN A 294
LEU A 293
 None
None
CS2  A 501 (-3.0A)
CS2  A 501 ( 4.5A)
 1.41A 3lslA-4im7A:
undetectable
3lslD-4im7A:
undetectable		 3lslA-4im7A:
19.01
3lslD-4im7A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 7 TYR A 347
MET A 288
ASN A 294
LEU A 293
 None
None
CS2  A 501 (-3.0A)
CS2  A 501 ( 4.5A)
 1.45A 3lslA-4im7A:
undetectable
3lslD-4im7A:
undetectable		 3lslA-4im7A:
19.01
3lslD-4im7A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 7 TYR A 347
MET A 292
ASN A 294
LEU A 293
 None
None
CS2  A 501 (-3.0A)
CS2  A 501 ( 4.5A)
 1.43A 3lslA-4im7A:
undetectable
3lslD-4im7A:
undetectable		 3lslA-4im7A:
19.01
3lslD-4im7A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 6 TYR A 347
MET A 288
ASN A 294
LEU A 293
 None
None
CS2  A 501 (-3.0A)
CS2  A 501 ( 4.5A)
 1.43A 3lslG-4im7A:
undetectable		 3lslG-4im7A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 6 TYR A 347
MET A 292
ASN A 294
LEU A 293
 None
None
CS2  A 501 (-3.0A)
CS2  A 501 ( 4.5A)
 1.41A 3lslG-4im7A:
undetectable		 3lslG-4im7A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 6 VAL A 162
VAL A 196
ILE A 125
ARG A 170
 None
None
NAI  A 502 (-3.7A)
None
 1.09A 3ms9A-4im7A:
undetectable		 3ms9A-4im7A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 6 VAL A 162
VAL A 196
ILE A 125
ARG A 170
 None
None
NAI  A 502 (-3.7A)
None
 1.08A 3mssA-4im7A:
undetectable		 3mssA-4im7A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 6 VAL A 162
VAL A 196
ILE A 125
ARG A 170
 None
None
NAI  A 502 (-3.7A)
None
 1.11A 3mssC-4im7A:
undetectable		 3mssC-4im7A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_DIFB585_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		5 / 12 VAL A 441
LEU A 444
GLY A 402
ALA A 401
LEU A 473
 None
 1.10A 3n8yB-4im7A:
undetectable		 3n8yB-4im7A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_1
(PROTEASE)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		5 / 9 ALA A 201
ASP A 205
GLY A 161
VAL A 216
ILE A 212
 None
 1.13A 3nuoA-4im7A:
undetectable		 3nuoA-4im7A:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_B_FLPB701_1
(CYCLOOXYGENASE-2)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		5 / 11 VAL A 441
LEU A 444
VAL A 400
GLY A 402
ALA A 401
 None
 1.18A 3pghB-4im7A:
undetectable		 3pghB-4im7A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_C_IMNC701_1
(CYCLOOXYGENASE-2)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		5 / 12 VAL A 441
LEU A 444
VAL A 400
GLY A 402
ALA A 401
 None
 1.14A 4coxC-4im7A:
undetectable		 4coxC-4im7A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 4 SER A 122
ILE A 260
TYR A  55
PRO A 219
 None
 1.45A 4jkuB-4im7A:
2.5		 4jkuB-4im7A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_2
(SUGAR KINASE)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 4 SER A 122
ILE A 260
TYR A  55
PRO A 219
 None
 1.45A 4k8pA-4im7A:
2.4		 4k8pA-4im7A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_2
(SUGAR KINASE)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 4 SER A 122
ILE A 260
TYR A  55
PRO A 219
 None
 1.44A 4k8pB-4im7A:
2.3		 4k8pB-4im7A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_2
(SUGAR KINASE)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 4 SER A 122
ILE A 260
TYR A  55
PRO A 219
 None
 1.45A 4k8tA-4im7A:
2.5		 4k8tA-4im7A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_2
(SUGAR KINASE)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 4 SER A 122
ILE A 260
TYR A  55
PRO A 219
 None
 1.43A 4k8tB-4im7A:
2.3		 4k8tB-4im7A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_2
(SUGAR KINASE)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 4 SER A 122
ILE A 260
TYR A  55
PRO A 219
 None
 1.42A 4k93A-4im7A:
2.7		 4k93A-4im7A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_2
(SUGAR KINASE)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 4 SER A 122
ILE A 260
TYR A  55
PRO A 219
 None
 1.44A 4k93B-4im7A:
3.2		 4k93B-4im7A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_2
(SUGAR KINASE)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 4 SER A 122
ILE A 260
TYR A  55
PRO A 219
 None
 1.45A 4k9cA-4im7A:
2.5		 4k9cA-4im7A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_2
(SUGAR KINASE)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 4 SER A 122
ILE A 260
TYR A  55
PRO A 219
 None
 1.45A 4k9cB-4im7A:
2.8		 4k9cB-4im7A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_2
(SUGAR KINASE)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 4 SER A 122
ILE A 260
TYR A  55
PRO A 219
 None
 1.45A 4k9iA-4im7A:
2.4		 4k9iA-4im7A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_2
(SUGAR KINASE)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 4 SER A 122
ILE A 260
TYR A  55
PRO A 219
 None
 1.45A 4k9iB-4im7A:
2.3		 4k9iB-4im7A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 4 SER A 122
ILE A 260
TYR A  55
PRO A 219
 None
 1.44A 4kadA-4im7A:
2.7		 4kadA-4im7A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 4 SER A 122
ILE A 260
TYR A  55
PRO A 219
 None
 1.44A 4kadB-4im7A:
2.6		 4kadB-4im7A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 8 THR A 158
LEU A 141
VAL A 146
VAL A 164
 None
 1.10A 4l4dA-4im7A:
undetectable		 4l4dA-4im7A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 8 THR A 158
LEU A 141
VAL A 146
VAL A 164
 None
 1.11A 4l4fA-4im7A:
undetectable		 4l4fA-4im7A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 4 SER A 122
ILE A 260
TYR A  55
PRO A 219
 None
 1.43A 4lbxA-4im7A:
2.5		 4lbxA-4im7A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 4 SER A 122
ILE A 260
TYR A  55
PRO A 219
 None
 1.43A 4lbxB-4im7A:
2.3		 4lbxB-4im7A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 4 SER A 122
ILE A 260
TYR A  55
PRO A 219
 None
 1.41A 4lc4A-4im7A:
2.5		 4lc4A-4im7A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 4 SER A 122
ILE A 260
TYR A  55
PRO A 219
 None
 1.42A 4lc4B-4im7A:
2.4		 4lc4B-4im7A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 6 ALA A 159
THR A 160
VAL A 162
VAL A 180
 NAI  A 502 ( 4.7A)
None
None
None
 1.06A 5eckA-4im7A:
undetectable		 5eckA-4im7A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 6 ALA A 159
THR A 160
VAL A 162
VAL A 180
 NAI  A 502 ( 4.7A)
None
None
None
 1.04A 5eckD-4im7A:
undetectable		 5eckD-4im7A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKL_B_SAMB8009_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN,HISTONE H3.1
PEPTIDE,ZINC FINGER
DOMAIN-CONTAINING
PROTEIN)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		5 / 12 GLY A 304
TYR A 305
TYR A 406
LEU A 328
MET A 379
 None
SO4  A 503 (-4.8A)
None
None
None
 1.20A 5kklB-4im7A:
undetectable		 5kklB-4im7A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_A_CVIA608_0
(ACETYLCHOLINESTERASE)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 7 ASP A 184
THR A 124
LEU A 123
VAL A 196
 NAI  A 502 (-3.8A)
NAI  A 502 (-4.3A)
None
None
 1.09A 5ov9A-4im7A:
undetectable		 5ov9A-4im7A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9A_A_AR3A201_1
(PEPTIDYL-TRNA
HYDROLASE)		 4im7 HYPOTHETICAL
OXIDOREDUCTASE YDFI
(Escherichia
coli) 		4 / 6 ALA A 201
GLN A 202
GLN A 210
ASP A 214
 None
 1.48A 5y9aA-4im7A:
undetectable		 5y9aA-4im7A:
17.00