SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4im8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4im8 ADVANCED GLYCATION
END-PRODUCTS
RECEPTOR
(Mus
musculus) 		4 / 7 VAL A 172
SER A 189
LEU A 163
HIS A 157
 None
 0.99A 2f78A-4im8A:
undetectable		 2f78A-4im8A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4im8 ADVANCED GLYCATION
END-PRODUCTS
RECEPTOR
(Mus
musculus) 		4 / 7 VAL A 172
SER A 189
LEU A 163
HIS A 157
 None
 1.06A 2f78B-4im8A:
undetectable		 2f78B-4im8A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4im8 ADVANCED GLYCATION
END-PRODUCTS
RECEPTOR
(Mus
musculus) 		4 / 6 VAL A 172
SER A 189
LEU A 163
HIS A 157
 None
 1.03A 2f8dA-4im8A:
undetectable		 2f8dA-4im8A:
22.99