SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4im9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_2
(DNA GYRASE SUBUNIT B)		 4im9 DNA PRIMASE
(Vibrio
cholerae) 		3 / 3 ASP A 103
PHE A  98
VAL A  31
 None
 0.71A 1kijB-4im9A:
undetectable		 1kijB-4im9A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_D_T44D328_1
(5-HYDROXYISOURATE
HYDROLASE)		 4im9 DNA PRIMASE
(Vibrio
cholerae) 		5 / 9 HIS A  39
LEU A  40
LEU A  45
LEU A 142
LEU A 106
 None
 1.37A 3q1eB-4im9A:
undetectable
3q1eD-4im9A:
undetectable		 3q1eB-4im9A:
17.48
3q1eD-4im9A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 4im9 DNA PRIMASE
(Vibrio
cholerae) 		5 / 11 TYR A  27
LEU A  97
ALA A  19
GLN A  23
ILE A  22
 None
 1.40A 3qelA-4im9A:
undetectable
3qelB-4im9A:
undetectable		 3qelA-4im9A:
16.93
3qelB-4im9A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_B_QELB503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 4im9 DNA PRIMASE
(Vibrio
cholerae) 		5 / 11 TYR A  27
LEU A  97
ALA A  19
GLN A  23
ILE A  22
 None
 1.39A 5ewjA-4im9A:
undetectable
5ewjB-4im9A:
undetectable		 5ewjA-4im9A:
16.36
5ewjB-4im9A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 4im9 DNA PRIMASE
(Vibrio
cholerae) 		3 / 3 ASP A  16
ASN A  24
GLN A  94
 None
 0.80A 5k7uA-4im9A:
undetectable		 5k7uA-4im9A:
21.21