SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4imm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J8U_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		4 / 7 VAL A 184
SER A 160
LEU A 158
ALA A 204
 None
 0.84A 1j8uA-4immA:
undetectable		 1j8uA-4immA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_1
(PROTEASE)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		5 / 12 LEU A 176
ASP A 118
ILE A 117
VAL A 166
VAL A 164
 None
None
None
NA  A 404 (-3.6A)
None
 0.81A 2nnkA-4immA:
undetectable		 2nnkA-4immA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_3
(PROTEASE)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		5 / 12 LEU A 176
ASP A 118
ILE A 117
VAL A 166
VAL A 164
 None
None
None
NA  A 404 (-3.6A)
None
 0.87A 2nnkB-4immA:
undetectable		 2nnkB-4immA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_2
(PROTEASE)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		5 / 11 LEU A 176
ILE A 117
ILE A 126
VAL A 166
VAL A 164
 None
None
None
NA  A 404 (-3.6A)
None
 0.91A 2nnpB-4immA:
undetectable		 2nnpB-4immA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_B_FOLB1188_0
(DIHYDROFOLATE
REDUCTASE)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		5 / 12 ILE A 126
ALA A 124
LEU A  80
GLN A 104
LEU A  54
 None
None
None
None
NA  A 405 ( 3.9A)
 1.27A 2w3mB-4immA:
undetectable		 2w3mB-4immA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		4 / 8 THR A 128
ILE A 134
ASP A 109
SER A 130
 None
 1.10A 2xytH-4immA:
undetectable		 2xytH-4immA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		4 / 7 THR A 128
ILE A 134
ASP A 109
SER A 130
 None
 1.05A 2xytI-4immA:
undetectable		 2xytI-4immA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A7E_A_SAMA216_1
(CATECHOL
O-METHYLTRANSFERASE)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		4 / 6 GLY A 214
ILE A 212
ILE A 219
ASP A 249
 None
None
None
CA  A 407 (-3.3A)
 0.99A 3a7eA-4immA:
undetectable		 3a7eA-4immA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		4 / 8 VAL A 184
ILE A 212
VAL A 210
GLY A 227
 None
 0.62A 3hjoB-4immA:
undetectable		 3hjoB-4immA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		4 / 7 GLY A 171
THR A 172
ILE A 173
THR A 232
 None
 0.90A 4acaC-4immA:
undetectable		 4acaC-4immA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		4 / 7 ASP A 216
GLY A 217
VAL A 191
HIS A 220
 None
 0.86A 4c5nA-4immA:
undetectable		 4c5nA-4immA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		4 / 7 ARG A 234
GLY A 217
ALA A 271
GLN A 246
 None
 0.91A 4g0uB-4immA:
undetectable		 4g0uB-4immA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_F_ASWF101_1
(DNA TOPOISOMERASE
2-BETA)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		4 / 6 ARG A 234
GLY A 217
ALA A 271
GLN A 246
 None
 0.96A 4g0uA-4immA:
undetectable		 4g0uA-4immA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_B_MTXB603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		5 / 12 ALA A 135
LEU A 133
LYS A 163
SER A 160
SER A 153
 None
None
None
None
NA  A 404 (-3.0A)
 1.13A 4ky8B-4immA:
undetectable		 4ky8B-4immA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		5 / 9 PRO A 156
ALA A 157
GLY A 198
SER A 152
GLY A 113
 None
NA  A 404 (-4.5A)
MG  A 408 ( 3.6A)
None
None
 1.31A 4mm5A-4immA:
undetectable		 4mm5A-4immA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NED_A_PFNA709_1
(LACTOTRANSFERRIN)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		4 / 6 ASP A 251
VAL A 191
SER A 151
ALA A 155
 CA  A 407 ( 2.3A)
None
None
NA  A 404 (-4.2A)
 0.94A 4nedA-4immA:
undetectable		 4nedA-4immA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_C_MTXC604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		5 / 12 ALA A 135
LEU A 133
LYS A 163
SER A 160
SER A 153
 None
None
None
None
NA  A 404 (-3.0A)
 1.29A 4q0dC-4immA:
undetectable		 4q0dC-4immA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_D_MTXD604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		5 / 12 ALA A 135
LEU A 133
LYS A 163
SER A 160
SER A 153
 None
None
None
None
NA  A 404 (-3.0A)
 1.29A 4q0dD-4immA:
undetectable		 4q0dD-4immA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		4 / 8 PHE A 174
THR A 189
SER A 170
ASP A 216
 None
 1.11A 4qb9D-4immA:
undetectable		 4qb9D-4immA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J7W_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		5 / 12 LEU A 319
LEU A 325
GLY A 301
ILE A 340
ALA A 341
 None
None
NA  A 402 (-3.3A)
None
None
 1.12A 5j7wC-4immA:
undetectable		 5j7wC-4immA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM8_B_L8PB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		4 / 8 GLN A  48
ALA A 380
GLN A 381
SER A 382
 None
None
NA  A 401 (-2.9A)
None
 1.14A 5km8A-4immA:
undetectable
5km8B-4immA:
undetectable		 5km8A-4immA:
18.21
5km8B-4immA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0I_B_ACTB303_0
(SWI5-DEPENDENT HO
EXPRESSION PROTEIN 2)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		4 / 5 VAL A 342
ASN A 322
ASP A 324
LEU A 325
 None
 1.08A 5m0iB-4immA:
undetectable		 5m0iB-4immA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_A_SAMA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		4 / 4 ASP A 305
SER A 303
ASP A 307
HIS A 323
 None
 1.44A 5wyqB-4immA:
undetectable		 5wyqB-4immA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		5 / 12 VAL A 299
LEU A 270
GLY A 316
TRP A 320
VAL A 308
 None
 1.18A 6a94B-4immA:
undetectable		 6a94B-4immA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		5 / 10 GLY A 131
LEU A 149
VAL A 164
ALA A 157
LEU A 176
 None
None
None
NA  A 404 (-4.5A)
None
 1.09A 6czmA-4immA:
undetectable
6czmC-4immA:
undetectable		 6czmA-4immA:
22.12
6czmC-4immA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_0
(PROTEASE)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		5 / 12 LEU A 176
ASP A 118
ILE A 117
VAL A 166
VAL A 164
 None
None
None
NA  A 404 (-3.6A)
None
 0.88A 6dh0A-4immA:
undetectable		 6dh0A-4immA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QYA_B_FOZB401_0
(THYMIDYLATE SYNTHASE)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		5 / 12 LEU A 319
LEU A 325
GLY A 301
ILE A 340
ALA A 341
 None
None
NA  A 402 (-3.3A)
None
None
 1.12A 6qyaB-4immA:
undetectable		 6qyaB-4immA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QYA_D_FOZD401_0
(THYMIDYLATE SYNTHASE)		 4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Moraxella
catarrhalis) 		5 / 12 LEU A 319
LEU A 325
GLY A 301
ILE A 340
ALA A 341
 None
None
NA  A 402 (-3.3A)
None
None
 1.14A 6qyaD-4immA:
undetectable		 6qyaD-4immA:
22.04