SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4in0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 4in0 THIOREDOXIN-LIKE
PROTEIN 4B
(Homo
sapiens) 		4 / 5 ASP A  62
VAL A  63
GLY A  31
ASP A  33
 None
 1.21A 3w9tA-4in0A:
undetectable		 3w9tA-4in0A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 4in0 THIOREDOXIN-LIKE
PROTEIN 4B
(Homo
sapiens) 		4 / 5 ASP A  62
VAL A  63
GLY A  31
ASP A  33
 None
 1.21A 3w9tB-4in0A:
undetectable		 3w9tB-4in0A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 4in0 THIOREDOXIN-LIKE
PROTEIN 4B
(Homo
sapiens) 		4 / 5 ASP A  62
VAL A  63
GLY A  31
ASP A  33
 None
 1.21A 3w9tC-4in0A:
undetectable		 3w9tC-4in0A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 4in0 THIOREDOXIN-LIKE
PROTEIN 4B
(Homo
sapiens) 		4 / 5 ASP A  62
VAL A  63
GLY A  31
ASP A  33
 None
 1.21A 3w9tD-4in0A:
undetectable		 3w9tD-4in0A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 4in0 THIOREDOXIN-LIKE
PROTEIN 4B
(Homo
sapiens) 		4 / 5 ASP A  62
VAL A  63
GLY A  31
ASP A  33
 None
 1.21A 3w9tE-4in0A:
undetectable		 3w9tE-4in0A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 4in0 THIOREDOXIN-LIKE
PROTEIN 4B
(Homo
sapiens) 		4 / 5 ASP A  62
VAL A  63
GLY A  31
ASP A  33
 None
 1.21A 3w9tF-4in0A:
undetectable		 3w9tF-4in0A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 4in0 THIOREDOXIN-LIKE
PROTEIN 4B
(Homo
sapiens) 		4 / 5 ASP A  62
VAL A  63
GLY A  31
ASP A  33
 None
 1.20A 3w9tG-4in0A:
undetectable		 3w9tG-4in0A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_2
(CYTOCHROME P450 2C9)		 4in0 THIOREDOXIN-LIKE
PROTEIN 4B
(Homo
sapiens) 		3 / 3 LEU A  26
VAL A  14
ASP A  15
 None
 0.58A 5x23A-4in0A:
undetectable		 5x23A-4in0A:
17.77