SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4inl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_0
(MODIFICATION
METHYLASE RSRI)		 4inl SERINE PROTEASE SPLD
(Staphylococcus
aureus) 		5 / 12 ASP A  72
THR A  19
GLY A 157
SER A 158
ALA A  80
 None
 1.20A 1nw5A-4inlA:
undetectable		 1nw5A-4inlA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 4inl SERINE PROTEASE SPLD
(Staphylococcus
aureus) 		4 / 8 ILE A 160
LEU A 161
PHE A 103
GLY A  17
 None
 1.02A 1os6A-4inlA:
undetectable		 1os6A-4inlA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_A_SAMA500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 4inl SERINE PROTEASE SPLD
(Staphylococcus
aureus) 		5 / 11 GLU A 166
ALA A 167
ILE A 160
ALA A 109
PHE A  27
 None
 1.21A 2admA-4inlA:
undetectable		 2admA-4inlA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_B_SAMB500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 4inl SERINE PROTEASE SPLD
(Staphylococcus
aureus) 		5 / 11 GLU A 166
ALA A 167
ILE A 160
ALA A 109
PHE A  27
 None
 1.21A 2admB-4inlA:
undetectable		 2admB-4inlA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4inl SERINE PROTEASE SPLD
(Staphylococcus
aureus) 		3 / 3 LYS A 194
TYR A 188
PRO A 191
 None
 0.95A 2j9cC-4inlA:
undetectable		 2j9cC-4inlA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		 4inl SERINE PROTEASE SPLD
(Staphylococcus
aureus) 		5 / 12 HIS A  39
ASP A  78
GLY A 154
SER A 156
ALA A 173
 None
 0.73A 3keeB-4inlA:
13.4		 3keeB-4inlA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		 4inl SERINE PROTEASE SPLD
(Staphylococcus
aureus) 		5 / 12 HIS A  39
ASP A  78
GLY A 154
SER A 156
ALA A 173
 None
 0.77A 3keeC-4inlA:
12.8		 3keeC-4inlA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		 4inl SERINE PROTEASE SPLD
(Staphylococcus
aureus) 		5 / 12 HIS A  39
ASP A  78
GLY A 154
SER A 156
ALA A 173
 None
 0.77A 3keeD-4inlA:
13.3		 3keeD-4inlA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4inl SERINE PROTEASE SPLD
(Staphylococcus
aureus) 		5 / 12 HIS A  39
ASP A  78
GLY A 154
SER A 156
ALA A 173
 None
 0.77A 3sueA-4inlA:
9.0		 3sueA-4inlA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4inl SERINE PROTEASE SPLD
(Staphylococcus
aureus) 		5 / 12 HIS A  39
ASP A  78
GLY A 154
SER A 156
ALA A 173
 None
 0.75A 3sueC-4inlA:
11.8		 3sueC-4inlA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4inl SERINE PROTEASE SPLD
(Staphylococcus
aureus) 		5 / 11 HIS A  39
ASP A  78
GLY A 154
SER A 156
ALA A 173
 None
 0.78A 3sufC-4inlA:
11.7		 3sufC-4inlA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4inl SERINE PROTEASE SPLD
(Staphylococcus
aureus) 		5 / 12 HIS A  39
ASP A  78
GLY A 154
SER A 156
ALA A 173
 None
 0.67A 3sufD-4inlA:
8.7		 3sufD-4inlA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 4inl SERINE PROTEASE SPLD
(Staphylococcus
aureus) 		4 / 8 ILE A 160
ILE A 105
PHE A 103
GLY A  17
 None
 0.97A 4hdlA-4inlA:
undetectable		 4hdlA-4inlA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 4inl SERINE PROTEASE SPLD
(Staphylococcus
aureus) 		3 / 3 TYR A  65
ARG A  94
SER A  88
 None
 0.97A 4khpI-4inlA:
undetectable
4khpJ-4inlA:
undetectable		 4khpI-4inlA:
23.36
4khpJ-4inlA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 4inl SERINE PROTEASE SPLD
(Staphylococcus
aureus) 		4 / 5 HIS A  39
ALA A 173
SER A 156
GLY A 157
 None
 1.12A 5yodB-4inlA:
10.5		 5yodB-4inlA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 4inl SERINE PROTEASE SPLD
(Staphylococcus
aureus) 		5 / 12 HIS A  39
ASP A  78
GLY A 154
SER A 156
ALA A 173
 None
 0.72A 6c2mC-4inlA:
12.2		 6c2mC-4inlA:
17.84