SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ios'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4ios LLAMA NANOBODY 11
(Lama
glama) 		3 / 3 ASP D 111
TYR D 110
LYS D 104
 None
 0.94A 2othA-4iosD:
undetectable		 2othA-4iosD:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_D_ASDD1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 4ios BPP
(Lactococcus
phage
TP901-1) 		4 / 7 TYR A  88
ILE A  90
GLY A 156
PHE A 132
 None
 1.00A 2vctD-4iosA:
undetectable		 2vctD-4iosA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4ios BPP
(Lactococcus
phage
TP901-1) 		4 / 7 CYH A 119
ILE A 136
PRO A 161
ASP A 163
 None
 1.06A 4w5oA-4iosA:
undetectable		 4w5oA-4iosA:
7.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4ios BPP
(Lactococcus
phage
TP901-1) 		4 / 7 CYH A 119
ILE A 136
PRO A 161
ASP A 163
 None
 1.07A 4z4eA-4iosA:
undetectable		 4z4eA-4iosA:
7.20