SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4iov'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_B_TACB1888_1
(ELONGATION FACTOR
EF-TU)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 5 THR A 714
SER A 707
ASP A 713
SER A 706
 None
 1.40A 2hdnA-4iovA:
undetectable
2hdnB-4iovA:
undetectable
2hdnD-4iovA:
undetectable		 2hdnA-4iovA:
4.52
2hdnB-4iovA:
17.76
2hdnD-4iovA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_D_TACD2888_1
(ELONGATION FACTOR
EF-TU)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 5 SER A 706
THR A 714
SER A 707
ASP A 713
 None
 1.42A 2hdnB-4iovA:
undetectable
2hdnC-4iovA:
undetectable
2hdnD-4iovA:
undetectable		 2hdnB-4iovA:
17.76
2hdnC-4iovA:
4.52
2hdnD-4iovA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		3 / 3 ARG A 569
GLY A 526
PRO A 527
 None
 0.64A 2hreD-4iovA:
undetectable		 2hreD-4iovA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TOD_A_DMOA700_1
(PROTEIN (ORNITHINE
DECARBOXYLASE))		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 6 TYR A 272
ASP A 274
ASP A 346
TYR A 343
 None
 1.44A 2todA-4iovA:
undetectable
2todB-4iovA:
undetectable		 2todA-4iovA:
20.49
2todB-4iovA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_B_ECNB1406_1
(CYTOCHROME P450 130)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		5 / 11 ASP A 608
PRO A 521
MET A 522
LEU A 537
TYR A 610
 None
 1.42A 2uvnB-4iovA:
undetectable		 2uvnB-4iovA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 6 GLU A 560
ALA A 565
ASN A 567
ALA A 564
 None
 1.00A 2zgwB-4iovA:
undetectable		 2zgwB-4iovA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		3 / 3 SER A 559
GLN A 536
PHE A 557
 None
 0.69A 3g4lC-4iovA:
undetectable		 3g4lC-4iovA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 7 PHE A 645
GLY A 271
GLY A 367
PHE A 402
 None
 0.90A 3ko0M-4iovA:
undetectable
3ko0P-4iovA:
undetectable		 3ko0M-4iovA:
9.57
3ko0P-4iovA:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		3 / 3 TYR A 610
ARG A 727
SER A 726
 None
 1.15A 4dr2I-4iovA:
undetectable
4dr2J-4iovA:
undetectable		 4dr2I-4iovA:
12.45
4dr2J-4iovA:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		3 / 3 GLY A 541
GLU A 720
THR A 719
 None
 0.59A 4kouA-4iovA:
undetectable		 4kouA-4iovA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		3 / 3 TYR A 610
ARG A 727
SER A 726
 None
 1.10A 4lf7I-4iovA:
undetectable
4lf7J-4iovA:
0.2		 4lf7I-4iovA:
12.45
4lf7J-4iovA:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		3 / 3 TYR A 610
ARG A 727
SER A 726
 None
 1.10A 4lf8I-4iovA:
undetectable
4lf8J-4iovA:
0.2		 4lf8I-4iovA:
12.45
4lf8J-4iovA:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 7 PRO A 299
PHE A 635
TRP A 616
TYR A 343
 None
 1.39A 4v2yA-4iovA:
undetectable		 4v2yA-4iovA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 7 PRO A 299
PHE A 635
TRP A 616
TYR A 343
 None
 1.39A 4v2yB-4iovA:
undetectable		 4v2yB-4iovA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_C_EF2C151_1
(CEREBLON ISOFORM 4)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 7 PRO A 299
PHE A 635
TRP A 616
TYR A 343
 None
 1.46A 4v2yC-4iovA:
undetectable		 4v2yC-4iovA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_A_Y70A151_1
(CEREBLON ISOFORM 4)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 7 PRO A 299
PHE A 635
TRP A 616
TYR A 343
 None
 1.42A 4v2zA-4iovA:
undetectable		 4v2zA-4iovA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 8 PRO A 299
PHE A 635
TRP A 616
TYR A 343
 None
 1.36A 4v2zB-4iovA:
undetectable		 4v2zB-4iovA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_C_Y70C151_1
(CEREBLON ISOFORM 4)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 8 PRO A 299
PHE A 635
TRP A 616
TYR A 343
 None
 1.44A 4v2zC-4iovA:
undetectable		 4v2zC-4iovA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_A_LVYA151_1
(CEREBLON ISOFORM 4)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 7 PRO A 299
PHE A 635
TRP A 616
TYR A 343
 None
 1.41A 4v30A-4iovA:
undetectable		 4v30A-4iovA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 8 PRO A 299
PHE A 635
TRP A 616
TYR A 343
 None
 1.29A 4v30B-4iovA:
undetectable		 4v30B-4iovA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 6 LEU A 341
TYR A 343
PRO A 342
TYR A 366
 None
 1.33A 4z4gA-4iovA:
undetectable		 4z4gA-4iovA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMH_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 7 PRO A 299
PHE A 635
TRP A 616
TYR A 343
 None
 1.47A 5amhA-4iovA:
undetectable		 5amhA-4iovA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 7 PRO A 299
PHE A 635
TRP A 616
TYR A 343
 None
 1.40A 5amiA-4iovA:
undetectable		 5amiA-4iovA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 8 PRO A 299
PHE A 635
TRP A 616
TYR A 343
 None
 1.41A 5amiB-4iovA:
undetectable		 5amiB-4iovA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 7 PRO A 299
PHE A 635
TRP A 616
TYR A 343
 None
 1.40A 5amjA-4iovA:
undetectable		 5amjA-4iovA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 7 PRO A 299
PHE A 635
TRP A 616
TYR A 343
 None
 1.37A 5amjB-4iovA:
undetectable		 5amjB-4iovA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 7 PRO A 299
PHE A 635
TRP A 616
TYR A 343
 None
 1.36A 5amkB-4iovA:
undetectable		 5amkB-4iovA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_A_EF2A202_0
(CEREBLON ISOFORM 4)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 7 PRO A 299
PHE A 635
TRP A 616
TYR A 343
 None
 1.42A 5oh1A-4iovA:
undetectable		 5oh1A-4iovA:
8.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_B_EF2B202_0
(CEREBLON ISOFORM 4)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 7 PRO A 299
PHE A 635
TRP A 616
TYR A 343
 None
 1.35A 5oh1B-4iovA:
undetectable		 5oh1B-4iovA:
8.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_A_9V2A202_0
(CEREBLON ISOFORM 4)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 7 PRO A 299
PHE A 635
TRP A 616
TYR A 343
 None
 1.40A 5oh3A-4iovA:
undetectable		 5oh3A-4iovA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_B_9V2B202_0
(CEREBLON ISOFORM 4)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 7 PRO A 299
PHE A 635
TRP A 616
TYR A 343
 None
 1.38A 5oh3B-4iovA:
undetectable		 5oh3B-4iovA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 6 GLN A 643
PHE A 275
LEU A 353
PHE A 361
 None
 1.06A 5z86P-4iovA:
undetectable
5z86W-4iovA:
undetectable		 5z86P-4iovA:
14.13
5z86W-4iovA:
6.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4iov CAPSID PROTEIN VP1
(Adeno-associated
virus) 		4 / 6 GLN A 643
PHE A 275
LEU A 353
PHE A 361
 None
 1.09A 5zcoP-4iovA:
undetectable
5zcoW-4iovA:
undetectable		 5zcoP-4iovA:
14.13
5zcoW-4iovA:
6.65