SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ioy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)
4ioy FACT COMPLEX SUBUNIT
SPT16

(Saccharomyces
cerevisiae)
3 / 3 ASN X 726
HIS X 741
VAL X 758
None
0.91A 3elzB-4ioyX:
1.5
3elzB-4ioyX:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)
4ioy FACT COMPLEX SUBUNIT
SPT16

(Saccharomyces
cerevisiae)
4 / 8 HIS X 743
GLU X 826
ASP X 850
GLU X 866
PO4  X1001 (-3.8A)
None
None
None
1.27A 6mn4C-4ioyX:
undetectable
6mn4C-4ioyX:
21.54