SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ip4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		5 / 12 LEU A 145
GLY A  85
ALA A 334
LEU A 337
PHE A 148
 None
CO2  A 505 ( 4.1A)
None
None
None
 0.91A 1gs4A-4ip4A:
undetectable		 1gs4A-4ip4A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GXS_A_BEZA601_0
(P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
A
P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
B)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 7 GLY A 407
PRO A 129
SER A 409
ALA A 402
 None
 0.93A 1gxsA-4ip4A:
undetectable
1gxsB-4ip4A:
undetectable		 1gxsA-4ip4A:
20.98
1gxsB-4ip4A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		5 / 12 LEU A 151
ALA A 334
VAL A 154
GLN A 309
HIS A 108
 None
 1.13A 1kt4A-4ip4A:
undetectable		 1kt4A-4ip4A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NR6_A_DIFA501_1
(CYTOCHROME P450 2C5)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		5 / 9 LEU A 230
GLY A 191
ALA A 190
THR A 187
LEU A 237
 None
 0.70A 1nr6A-4ip4A:
undetectable		 1nr6A-4ip4A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_C_BEZC505_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 6 ILE A 245
PRO A 268
PHE A 265
ARG A 262
 None
 1.32A 1oniA-4ip4A:
undetectable
1oniC-4ip4A:
undetectable		 1oniA-4ip4A:
17.75
1oniC-4ip4A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 7 ASP A 246
MET A  26
ASP A  24
LYS A 216
 MG  A 503 (-2.6A)
None
GOL  A 501 (-3.7A)
MG  A 503 ( 3.9A)
 1.45A 1t03A-4ip4A:
undetectable		 1t03A-4ip4A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XL6_B_SPMB3001_1
(INWARD RECTIFIER
POTASSIUM CHANNEL)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 5 ALA A  35
TYR A  10
ALA A 113
TYR A  36
 None
 1.14A 1xl6A-4ip4A:
undetectable
1xl6B-4ip4A:
undetectable		 1xl6A-4ip4A:
21.95
1xl6B-4ip4A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_A_NCAA506_0
(NAD-DEPENDENT
DEACETYLASE 2)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 6 ALA A  34
ASN A  58
ILE A  62
ASP A  11
 None
 0.97A 1yc2A-4ip4A:
undetectable		 1yc2A-4ip4A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_D_NCAD510_0
(NAD-DEPENDENT
DEACETYLASE 2)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 5 ALA A  34
ASN A  58
ILE A  62
ASP A  11
 None
 0.96A 1yc2D-4ip4A:
undetectable		 1yc2D-4ip4A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA601_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		5 / 12 TYR A  32
GLY A  22
GLY A 191
THR A 188
ILE A  54
 GOL  A 501 (-4.5A)
GOL  A 501 (-3.2A)
None
None
None
 1.15A 2azxA-4ip4A:
undetectable		 2azxA-4ip4A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_B_TRPB603_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		5 / 12 TYR A  32
GLY A  22
GLY A 191
THR A 188
ILE A  54
 GOL  A 501 (-4.5A)
GOL  A 501 (-3.2A)
None
None
None
 1.18A 2azxB-4ip4A:
undetectable		 2azxB-4ip4A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 8 TYR A 381
SER A 189
TYR A  32
HIS A 386
 None
None
GOL  A 501 (-4.5A)
None
 1.38A 2bteD-4ip4A:
undetectable		 2bteD-4ip4A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H4J_A_NCAA1002_0
(NAD-DEPENDENT
DEACETYLASE)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 5 ALA A  34
ASN A  58
ILE A  62
ASP A  11
 None
 0.90A 2h4jA-4ip4A:
undetectable		 2h4jA-4ip4A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		5 / 12 LEU A 145
GLY A  85
ALA A 334
LEU A 337
PHE A 148
 None
CO2  A 505 ( 4.1A)
None
None
None
 0.96A 2oz7A-4ip4A:
undetectable		 2oz7A-4ip4A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 7 TRP A 131
TYR A 367
CYH A 371
TYR A 183
 None
 1.47A 2xytG-4ip4A:
undetectable		 2xytG-4ip4A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		3 / 3 CYH A 356
PRO A 392
ASP A 383
 None
 0.40A 3hlwB-4ip4A:
undetectable		 3hlwB-4ip4A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_A_SAMA465_0
(RRNA METHYLASE)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		5 / 12 ALA A 334
GLY A 328
GLY A 327
ASP A 366
LEU A 155
 None
 1.11A 3m6vA-4ip4A:
undetectable		 3m6vA-4ip4A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUV_B_ASDB126_1
(STEROID
DELTA-ISOMERASE)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		5 / 10 ASN A 330
LEU A 133
PHE A 408
VAL A 130
ASN A 116
 None
 1.50A 3nuvB-4ip4A:
undetectable		 3nuvB-4ip4A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_1
(16S RRNA METHYLASE)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		3 / 3 ASP A  21
GLU A 387
SER A 196
 None
 0.83A 3p2kA-4ip4A:
0.9		 3p2kA-4ip4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		5 / 11 ALA A  64
ASN A 116
GLY A 112
ALA A 111
VAL A  72
 None
 1.19A 3rukD-4ip4A:
undetectable		 3rukD-4ip4A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 4 LEU A 121
GLY A  47
LEU A  39
GLU A  46
 None
 1.08A 3tgvB-4ip4A:
undetectable		 3tgvB-4ip4A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 6 SER A 189
TYR A 381
VAL A 395
THR A 213
 None
 1.15A 3tneA-4ip4A:
undetectable		 3tneA-4ip4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 7 TRP A 119
LYS A 128
GLY A 407
PRO A 406
 None
 1.40A 3ucbB-4ip4A:
undetectable		 3ucbB-4ip4A:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		5 / 12 THR A  53
GLY A 112
ALA A 350
GLY A 351
MET A 362
 None
None
None
GOL  A 501 (-3.5A)
None
 1.24A 3v3oA-4ip4A:
undetectable		 3v3oA-4ip4A:
25.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 6 VAL A 118
LEU A  39
ILE A   4
VAL A  91
 None
 0.64A 4a9kA-4ip4A:
undetectable		 4a9kA-4ip4A:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 5 VAL A 118
LEU A  39
ILE A   4
VAL A  91
 None
 0.81A 4a9kB-4ip4A:
undetectable		 4a9kB-4ip4A:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_B_SAMB1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		5 / 12 HIS A 349
ASP A 246
TYR A  32
GLY A 351
GLY A 220
 GOL  A 501 (-3.8A)
MG  A 503 (-2.6A)
GOL  A 501 (-4.5A)
GOL  A 501 (-3.5A)
None
 1.16A 4blvB-4ip4A:
undetectable		 4blvB-4ip4A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_2
(MDR769 HIV-1
PROTEASE)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 6 ARG A 221
ASN A 248
GLY A 352
PRO A  30
 None
GOL  A 501 ( 3.8A)
None
GOL  A 501 ( 4.8A)
 0.96A 4l1aB-4ip4A:
undetectable		 4l1aB-4ip4A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_2
(BETA-LACTAMASE
CTX-M-14)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		3 / 3 CYH A 356
PRO A 392
ASP A 383
 None
 0.42A 4pm5A-4ip4A:
undetectable		 4pm5A-4ip4A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		5 / 12 ASP A 418
LEU A 421
LEU A  12
ILE A 410
GLY A  49
 None
 1.03A 4xi3B-4ip4A:
undetectable		 4xi3B-4ip4A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		5 / 11 ILE A 311
GLN A 320
LEU A 316
ALA A 296
VAL A 154
 None
 1.19A 5ji0A-4ip4A:
undetectable		 5ji0A-4ip4A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA510_1
(PROTON-GATED ION
CHANNEL)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		5 / 9 ALA A 106
ILE A 107
ILE A  65
ALA A  67
LEU A  68
 None
 1.12A 5mvmA-4ip4A:
undetectable
5mvmE-4ip4A:
undetectable		 5mvmA-4ip4A:
13.22
5mvmE-4ip4A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		5 / 12 MET A 300
GLY A 351
VAL A 382
TRP A 192
GLN A 249
 None
GOL  A 501 (-3.5A)
None
None
None
 1.44A 5uc3B-4ip4A:
undetectable		 5uc3B-4ip4A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		5 / 12 GLY A 354
GLY A 352
ALA A 350
ILE A 410
LEU A  50
 None
 1.17A 6b3aA-4ip4A:
undetectable		 6b3aA-4ip4A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_1
(RIFAMPIN
MONOOXYGENASE)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		5 / 12 GLY A  69
VAL A  72
PHE A  87
GLY A 328
GLY A 327
 None
 1.12A 6brdB-4ip4A:
undetectable		 6brdB-4ip4A:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 8 LEU A 133
GLU A 141
TRP A 122
THR A 126
 None
 1.11A 6c71B-4ip4A:
undetectable		 6c71B-4ip4A:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 8 VAL A 295
PRO A 268
ILE A 286
THR A 275
 None
 1.04A 6cduG-4ip4A:
undetectable
6cduH-4ip4A:
undetectable		 6cduG-4ip4A:
18.98
6cduH-4ip4A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 6 LEU A 316
TYR A 186
ASP A 246
GLU A 272
 None
None
MG  A 503 (-2.6A)
MG  A 503 (-2.9A)
 1.40A 6djzC-4ip4A:
undetectable		 6djzC-4ip4A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		5 / 12 VAL A 114
LEU A  39
ALA A 113
GLY A  49
LEU A   7
 None
 0.94A 6f6iA-4ip4A:
undetectable
6f6iB-4ip4A:
undetectable		 6f6iA-4ip4A:
12.23
6f6iB-4ip4A:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		5 / 12 VAL A 114
LEU A  39
ALA A 113
THR A  51
LEU A   7
 None
 0.85A 6f6iA-4ip4A:
undetectable
6f6iB-4ip4A:
undetectable		 6f6iA-4ip4A:
12.23
6f6iB-4ip4A:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 4ip4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN
(Ruegeria
sp.
TM1040) 		4 / 7 ALA A 117
GLY A  49
LEU A  50
GLY A 327
 None
 0.85A 6nm4A-4ip4A:
undetectable		 6nm4A-4ip4A:
19.71