SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4iq4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Kitasatospora
aureofaciens;
Influenza
A
virus)
10 / 10 GLY A  31
PHE A  32
SER A  98
MET A  99
LEU A 125
PHE A 163
TRP A 205
THR A 230
LEU A 231
HIS A 257
None
0.51A 1a8uA-4iq4A:
50.7
1a8uA-4iq4A:
98.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Kitasatospora
aureofaciens;
Influenza
A
virus)
10 / 10 GLY A  31
PHE A  32
SER A  98
MET A  99
LEU A 125
PHE A 163
TRP A 205
THR A 230
LEU A 231
HIS A 257
None
0.47A 1a8uB-4iq4A:
50.5
1a8uB-4iq4A:
98.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza
A
virus;
Kitasatospora
aureofaciens)
4 / 5 THR A 236
ASP A 228
HIS A 257
HIS A 224
None
1.03A 1ei6A-4iq4A:
undetectable
1ei6A-4iq4A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza
A
virus;
Kitasatospora
aureofaciens)
5 / 12 GLY A 405
ALA A 406
SER A 409
GLY A 412
LEU A 413
None
0.87A 1fe2A-4iq4A:
undetectable
1fe2A-4iq4A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza
A
virus;
Kitasatospora
aureofaciens)
5 / 12 VAL A 104
LEU A  46
PHE A 274
LEU A 275
ARG A  52
None
1.15A 1jffB-4iq4A:
4.0
1jffB-4iq4A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza
A
virus;
Kitasatospora
aureofaciens)
3 / 3 PHE A 164
LEU A  34
MET A  99
None
0.67A 1mx1D-4iq4A:
12.7
1mx1D-4iq4A:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Kitasatospora
aureofaciens;
Influenza
A
virus)
4 / 5 SER A  35
SER A  38
THR A 189
ASN A 185
None
1.28A 1yvpA-4iq4A:
4.0
1yvpA-4iq4A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza
A
virus;
Kitasatospora
aureofaciens)
5 / 12 VAL A 104
LEU A  46
PHE A 274
LEU A 275
ARG A  52
None
1.14A 2hxfB-4iq4A:
4.0
2hxfB-4iq4A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza
A
virus;
Kitasatospora
aureofaciens)
5 / 12 VAL A 104
LEU A  46
PHE A 274
LEU A 275
ARG A  52
None
1.14A 2hxhB-4iq4A:
4.0
2hxhB-4iq4A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza
A
virus;
Kitasatospora
aureofaciens)
5 / 12 VAL A 104
LEU A  46
PHE A 274
LEU A 275
ARG A  52
None
1.14A 2p4nB-4iq4A:
3.9
2p4nB-4iq4A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Kitasatospora
aureofaciens;
Influenza
A
virus)
4 / 6 ARG A  59
TYR A  56
THR A  82
ALA A  78
None
1.45A 2ql8A-4iq4A:
undetectable
2ql8B-4iq4A:
undetectable
2ql8A-4iq4A:
15.68
2ql8B-4iq4A:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza
A
virus;
Kitasatospora
aureofaciens)
5 / 12 VAL A 104
LEU A  46
PHE A 274
LEU A 275
ARG A  52
None
1.15A 2wbeB-4iq4A:
4.0
2wbeB-4iq4A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1413_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza
A
virus;
Kitasatospora
aureofaciens)
4 / 6 ALA A 198
ALA A 201
THR A 204
PHE A  76
None
0.84A 2xfhA-4iq4A:
undetectable
2xfhA-4iq4A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza
A
virus;
Kitasatospora
aureofaciens)
5 / 12 VAL A 104
LEU A  46
PHE A 274
LEU A 275
ARG A  52
None
1.15A 3dcoB-4iq4A:
3.9
3dcoB-4iq4A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DLC_A_SAMA220_0
(PUTATIVE
S-ADENOSYL-L-METHION
INE-DEPENDENT
METHYLTRANSFERASE)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Kitasatospora
aureofaciens;
Influenza
A
virus)
5 / 12 PHE A 121
TYR A  56
GLY A 102
GLY A 100
SER A 124
None
1.18A 3dlcA-4iq4A:
undetectable
3dlcA-4iq4A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza
A
virus;
Kitasatospora
aureofaciens)
5 / 12 VAL A 104
LEU A  46
PHE A 274
LEU A 275
ARG A  52
None
1.14A 3edlB-4iq4A:
3.9
3edlB-4iq4A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza
A
virus;
Kitasatospora
aureofaciens)
5 / 12 VAL A 104
LEU A  46
PHE A 274
LEU A 275
ARG A  52
None
1.13A 3iz0B-4iq4A:
3.9
3iz0B-4iq4A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA1_A_08YA600_1
(CYTOCHROME P450 3A4)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza
A
virus;
Kitasatospora
aureofaciens)
5 / 12 PHE A  97
ARG A 177
THR A 230
THR A 269
ALA A 264
None
1.33A 3ua1A-4iq4A:
undetectable
3ua1A-4iq4A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza
A
virus;
Kitasatospora
aureofaciens)
5 / 12 GLY A 405
ALA A 406
SER A 409
GLY A 412
LEU A 413
None
0.78A 4e1gA-4iq4A:
undetectable
4e1gA-4iq4A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza
A
virus;
Kitasatospora
aureofaciens)
5 / 12 GLY A 405
ALA A 406
SER A 409
GLY A 412
LEU A 413
None
0.76A 4e1gB-4iq4A:
undetectable
4e1gB-4iq4A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Kitasatospora
aureofaciens;
Influenza
A
virus)
4 / 7 PHE A  61
ASP A  57
PRO A  67
ILE A  29
None
1.02A 4pcuA-4iq4A:
undetectable
4pcuA-4iq4A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza
A
virus;
Kitasatospora
aureofaciens)
5 / 12 LEU A 322
LEU A 303
GLY A 344
GLU A 354
PHE A 362
None
1.31A 4retC-4iq4A:
2.2
4retC-4iq4A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Kitasatospora
aureofaciens;
Influenza
A
virus)
4 / 5 PRO A 219
VAL A 119
ALA A 247
PHE A 274
None
1.09A 4w5oA-4iq4A:
4.2
4w5oA-4iq4A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_A_HISA302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Kitasatospora
aureofaciens;
Influenza
A
virus)
5 / 10 GLY A 344
THR A 339
VAL A 346
LEU A 335
LEU A 311
None
1.31A 4yb6A-4iq4A:
undetectable
4yb6E-4iq4A:
undetectable
4yb6A-4iq4A:
21.43
4yb6E-4iq4A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_B_HISB302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Kitasatospora
aureofaciens;
Influenza
A
virus)
5 / 10 GLY A 344
THR A 339
VAL A 346
LEU A 335
LEU A 311
None
1.28A 4yb6B-4iq4A:
undetectable
4yb6C-4iq4A:
undetectable
4yb6B-4iq4A:
21.43
4yb6C-4iq4A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_C_HISC302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Kitasatospora
aureofaciens;
Influenza
A
virus)
5 / 10 GLY A 344
THR A 339
VAL A 346
LEU A 335
LEU A 311
None
1.30A 4yb6C-4iq4A:
undetectable
4yb6F-4iq4A:
undetectable
4yb6C-4iq4A:
21.43
4yb6F-4iq4A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_E_HISE302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Kitasatospora
aureofaciens;
Influenza
A
virus)
5 / 10 LEU A 335
LEU A 311
GLY A 344
THR A 339
VAL A 346
None
1.27A 4yb6D-4iq4A:
undetectable
4yb6E-4iq4A:
undetectable
4yb6D-4iq4A:
21.43
4yb6E-4iq4A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_F_HISF302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Kitasatospora
aureofaciens;
Influenza
A
virus)
5 / 10 LEU A 335
LEU A 311
GLY A 344
THR A 339
VAL A 346
None
1.28A 4yb6B-4iq4A:
undetectable
4yb6F-4iq4A:
undetectable
4yb6B-4iq4A:
21.43
4yb6F-4iq4A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA905_0
(PROTEIN ARGONAUTE-2)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Kitasatospora
aureofaciens;
Influenza
A
virus)
4 / 5 PRO A 219
VAL A 119
ALA A 247
PHE A 274
None
1.11A 4z4cA-4iq4A:
4.2
4z4cA-4iq4A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA904_0
(PROTEIN ARGONAUTE-2)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Kitasatospora
aureofaciens;
Influenza
A
virus)
4 / 5 PRO A 219
VAL A 119
ALA A 247
PHE A 274
None
1.10A 4z4dA-4iq4A:
undetectable
4z4dA-4iq4A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA906_0
(PROTEIN ARGONAUTE-2)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Kitasatospora
aureofaciens;
Influenza
A
virus)
4 / 5 PRO A 219
VAL A 119
ALA A 247
PHE A 274
None
1.10A 4z4eA-4iq4A:
3.8
4z4eA-4iq4A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z7F_C_FOLC201_0
(FOLATE ECF
TRANSPORTER)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Kitasatospora
aureofaciens;
Influenza
A
virus)
5 / 12 ALA A 198
PHE A 163
THR A 161
ASN A 185
LEU A  34
None
1.49A 4z7fC-4iq4A:
undetectable
4z7fC-4iq4A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Kitasatospora
aureofaciens;
Influenza
A
virus)
4 / 7 ILE A 148
PHE A 144
ARG A 229
LEU A 231
None
0.92A 5b1bN-4iq4A:
undetectable
5b1bW-4iq4A:
undetectable
5b1bN-4iq4A:
21.82
5b1bW-4iq4A:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza
A
virus;
Kitasatospora
aureofaciens)
5 / 12 VAL A 104
LEU A  46
PHE A 274
LEU A 275
ARG A  52
None
1.11A 5hnwB-4iq4A:
4.0
5hnwB-4iq4A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza
A
virus;
Kitasatospora
aureofaciens)
5 / 12 VAL A 104
LEU A  46
PHE A 274
LEU A 275
ARG A  52
None
1.17A 5hnyB-4iq4A:
4.0
5hnyB-4iq4A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza
A
virus;
Kitasatospora
aureofaciens)
5 / 12 VAL A 104
LEU A  46
ALA A 120
PHE A 274
ARG A  52
None
0.89A 5hnzB-4iq4A:
3.9
5hnzB-4iq4A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza
A
virus;
Kitasatospora
aureofaciens)
5 / 12 THR A 433
GLN A 436
CYH A 410
ALA A 426
GLY A 428
None
1.35A 5l5zH-4iq4A:
undetectable
5l5zI-4iq4A:
undetectable
5l5zH-4iq4A:
19.08
5l5zI-4iq4A:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Kitasatospora
aureofaciens;
Influenza
A
virus)
5 / 12 SER A  38
HIS A  37
PHE A  61
GLY A  62
GLY A 193
None
0.93A 5l6eA-4iq4A:
undetectable
5l6eA-4iq4A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_B_SAMB501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Kitasatospora
aureofaciens;
Influenza
A
virus)
5 / 12 LEU A  94
ALA A 120
ILE A  29
GLY A 100
LEU A 275
None
1.03A 5nfjB-4iq4A:
undetectable
5nfjB-4iq4A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_C_SAMC501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Kitasatospora
aureofaciens;
Influenza
A
virus)
5 / 12 LEU A  94
ALA A 120
ILE A  29
GLY A 100
LEU A 275
None
1.02A 5nfjC-4iq4A:
undetectable
5nfjC-4iq4A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza
A
virus;
Kitasatospora
aureofaciens)
4 / 5 ALA A 220
VAL A 218
PHE A 121
ILE A 116
None
1.03A 5of1A-4iq4A:
undetectable
5of1A-4iq4A:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza
A
virus;
Kitasatospora
aureofaciens)
4 / 5 ALA A 220
VAL A 218
PHE A 121
ILE A 116
None
0.98A 5of1B-4iq4A:
undetectable
5of1B-4iq4A:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Kitasatospora
aureofaciens;
Influenza
A
virus)
4 / 6 PRO A 219
VAL A 119
ALA A 247
PHE A 274
None
1.10A 5t7bA-4iq4A:
4.4
5t7bA-4iq4A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Kitasatospora
aureofaciens;
Influenza
A
virus)
4 / 8 PHE A 164
SER A  38
HIS A  30
PHE A 167
None
1.08A 5y2tB-4iq4A:
undetectable
5y2tB-4iq4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_A_TLFA300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Kitasatospora
aureofaciens;
Influenza
A
virus)
5 / 12 VAL A 294
ILE A 414
VAL A 421
VAL A 346
PHE A 345
None
1.23A 6ap6A-4iq4A:
32.0
6ap6A-4iq4A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_B_TLFB300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Kitasatospora
aureofaciens;
Influenza
A
virus)
5 / 12 VAL A 294
ILE A 414
VAL A 421
VAL A 346
PHE A 345
None
1.23A 6ap6B-4iq4A:
32.0
6ap6B-4iq4A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_1
(TUBULIN BETA CHAIN)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza
A
virus;
Kitasatospora
aureofaciens)
5 / 12 VAL A 104
LEU A  46
ALA A 120
PHE A 274
LEU A 275
None
1.16A 6ew0G-4iq4A:
4.2
6ew0G-4iq4A:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)
4iq4 NON-HAEM
BROMOPEROXIDASE
BPO-A2, MATRIX
PROTEIN 1

(Influenza
A
virus;
Kitasatospora
aureofaciens)
6 / 10 VAL A  95
LEU A 122
LEU A 260
LEU A  46
THR A  55
LEU A 271
None
1.08A 6f5uA-4iq4A:
undetectable
6f5uB-4iq4A:
undetectable
6f5uA-4iq4A:
11.06
6f5uB-4iq4A:
14.66