SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4iqn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2002_1
(SERUM ALBUMIN)		 4iqn PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		5 / 11 ARG C 140
LEU C   5
SER C 162
LEU C 163
VAL C 164
 MLY  C  53 ( 3.9A)
None
None
None
None
 1.06A 2bxeB-4iqnC:
undetectable		 2bxeB-4iqnC:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2002_1
(SERUM ALBUMIN)		 4iqn PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 8 ALA C  54
SER C 162
LEU C 163
VAL C 164
 MLY  C  53 ( 3.6A)
None
None
None
 0.68A 2bxgA-4iqnC:
undetectable		 2bxgA-4iqnC:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 4iqn PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		3 / 3 THR C  46
PRO C  49
TYR C 146
 None
 0.94A 2dxrA-4iqnC:
undetectable		 2dxrA-4iqnC:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 4iqn PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		5 / 12 VAL C  70
ILE C 125
ILE C 133
ILE C 148
ALA C 159
 None
 0.98A 2gj5A-4iqnC:
undetectable		 2gj5A-4iqnC:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 4iqn PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		3 / 3 SER C  77
GLU C  91
ASP C 105
 None
 0.75A 2zulA-4iqnC:
undetectable		 2zulA-4iqnC:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 4iqn PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		5 / 11 ILE C 171
LEU C   8
ILE C   9
VAL C  70
LEU C  62
 None
 1.25A 3a51A-4iqnC:
undetectable		 3a51A-4iqnC:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 4iqn PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		3 / 3 SER C  77
GLU C  91
ASP C 105
 None
 0.77A 3dmhA-4iqnC:
undetectable		 3dmhA-4iqnC:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4iqn PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		5 / 12 SER C  64
ILE C 170
TYR C 166
LEU C 167
LEU C  74
 None
 1.34A 3vn2A-4iqnC:
undetectable		 3vn2A-4iqnC:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 4iqn PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 7 TYR C  87
ARG C  35
ILE C 137
ALA C 121
 None
 0.92A 4lv9B-4iqnC:
undetectable		 4lv9B-4iqnC:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M7T_A_SAMA503_0
(BTRN)		 4iqn PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		5 / 11 TYR C 166
GLU C 145
TYR C 168
LEU C  62
SER C  64
 None
 1.48A 4m7tA-4iqnC:
undetectable		 4m7tA-4iqnC:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_2
(CDL2.3B)		 4iqn PUTATIVE CYTOPLASMIC
PROTEIN
(Salmonella
enterica) 		5 / 9 ILE C 135
PRO C  49
VAL C  12
LEU C   8
ILE C   9
 None
None
MLY  C  13 ( 3.1A)
None
None
 1.32A 5iepA-4iqnC:
undetectable		 5iepA-4iqnC:
19.21